ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Thromboembolic Events Are Increased in Heart and Lung Transplant Recipients Who Received Intra-Operative Recombinant Factor VIIa

    K. Schoeppler, J. Lindenfeld, D. Lyu, T. Grazia, J. Crossno, Jr, K. Vandervest, M. Zamora

    Pharmacy, Univ of CO Hospital, Aurora, CO; Cardiology, Univ of CO Medical Campus, Aurora; Pulmonary and Critical Care, Univ of CO Medical Campus, Aurora

    Recombinant Factor VIIa (rFVIIa) is often used intra-operatively for refractory bleeding in heart and lung transplant recipients (HTxR, LTxR). While this off-label use may help…
  • 2013 American Transplant Congress

    Role of Increased Autophagic Flux in Renal Tubular Epithelial Cells Undergoing Warm Reperfusion (WR) after Cold Ischemia (CI), The

    A. Jani, S. Jain, T. Nydam, C. Edelstein

    UC Denver, Aurora, CO

    Delayed graft function (DGF) is primarily caused by cold ischemia (CI) and warm reperfusion (WR). The mechanism by which CI/WR causes renal tubular epithelial cell…
  • 2013 American Transplant Congress

    Induction Immunosuppression and Subclinical Viremia in Pediatric Renal Transplantation

    J. Smith, S. Gantt, A. Dick, P. Healey, T. Nemeth, R. McDonald

    Pediatrics, University of Washington, Seattle; Transplant Surgery, University of Washington, Seattle; Pharmacy, Seattle Children's, Seattle

    Background: Infection is the leading cause of hospitalization in pediatric renal transplant recipients. The impact of specific immunosuppressive agents on the incidence of infectious complications…
  • 2013 American Transplant Congress

    Specific miRNA’s and Their Downstream Targets Are Associated with Acute Rejection in Pediatric Renal Allografts

    M. Vitalone, T. Sigdel, P. Khatri, S. Hsieh, A. Butte, M. Sarwal

    California Pacific Medical Center, San Francisco; Stanford University, Stanford

    BACKGROUND: miRNA’s are small RNA molecules involved in post-transcription mRNA regulation. A single miRNA may target whole functional pathways. miRNA's have been implicated to play…
  • 2013 American Transplant Congress

    High Incidence of De Novo Post-Transplant Skin Cancer among Caucasian Recipients after Kidney Transplantation – An Analysis of OPTN/UNOS Data

    Y. Cho, I. Hutchinson, T. Shah

    Mendez National Institute of Transplantation, LA, CA; USC Keck School of Medicine, LA, CA

    Background. Organ transplant recipients are at high risk of post-transplant skin cancer (PTSC) which presents a clinical challenge to physicians. It has been reported that…
  • 2013 American Transplant Congress

    Development of New Onset Hypertension in Living Kidney Donors: Are Multiple Renal Arteries a Risk Factor?

    M. Elramah, V. Patil, Y. Becker, B. Astor, D. Foley, V. Vidyasagar, R. Hofmann

    Div. of Nephrology, Univeristy of Wisconsin, Madison, WI; Dept of Surgery, University of Chicago, Chicago, IL; Div. of Transplant Surgery, University of Wisconsin, Madison, WI

    Background After donation, multiple renal arteries(MA) a remaining kidney may increase the risk of hypertension (HTN). Method This study is a continuation of previous cohort…
  • 2013 American Transplant Congress

    Everolimus Aggravates Tacrolimus-Induced Pancreatic Injury by Pharmacologic Interaction between Everolimus and Tacrolimus

    S. Piao, S. Lim, K. Doh, L. Jin, B. Chung, S. Heo, C. Yang

    Convergent Research Consortium for Immunologic Disease, Seoul, Republic of Korea; Transplantation Research Center, Seoul, Republic of Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary&s Hospital, The Catholic University of Korea, Seoul, Republic of Korea; Nephrology & Dialysis Unit, Department of Internal Medicine, Affiliated Hospital, YanBian University Medical College, JinLin, China

    This study was conducted to investigate the pharmacologic interaction between EVR and TAC at the blood and pancreas level. Male Sprague-Dawley (SD) was administrated with…
  • 2013 American Transplant Congress

    Single Versus Dual Kidney Discards: A Detailed Analysis

    L. Malinzak, A. Patel, D. Kim, J. Denny, L. Yessayan, M. Goggins, M. Weitzer

    Transplant Institute, Henry Ford Health System, Detroit, MI; Wayne State University, Detroit, MI

    An ideal kidney allocation system should maximize organ utilization and minimize organ discard rates. It is important to understand the most common reasons why kidneys…
  • 2013 American Transplant Congress

    Association of HLA-A, B, C, DR, and DQ Matching with Rejection and Survival in Pancreas Transplantation

    E. Finger, D. Radosevich, T. Dunn, A. Kukla, J. Lohlun, D. Sutherland, T. Pruett, R. Kandaswamy

    University of Minnesota, Minneapolis, MN

    Objective: Determine the impact of HLA matching on acute cellular rejection (ACR), and graft and patient survival in pancreas txp.Methods: Retrospective review of 1,063 sequential…
  • 2013 American Transplant Congress

    Protection from Prolonged Cold Ischemia (CI) of Several Days Duration Is Mediated by Anti-Apoptotic phosphoBAD during Hibernation

    A. Jani, S. Jain, T. Nydam, C. Edelstein

    UCDenver, Denver, CO

    Donor kidney cold (4°C) ischemia (CI) of >30 hrs is associated with increased apoptosis of renal tubular epithelial cells (RTEC) and is an important cause…
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