2013 American Transplant Congress
Identification of Independent Risk Factors for De Novo DSA Development through Prospective Monitoring
The Methodist Hospital, Houston, TX
Background: Donor specific anti-human leukocyte antigen (HLA) antibodies (DSA) after renal transplant have been associated with poor outcomes in the form of renal dysfunction, increased…2013 American Transplant Congress
Chronic Opioid Usage Early after Kidney Transplantation
Introduction: Chronic opioids usage (COU) is common among patients with end stage renal disease (ESRD) receiving dialysis treatment and associated with poor clinical outcomes. We…2013 American Transplant Congress
Normothermic Oxygenated Machine Preservation Reduces Reperfusion Injury of DCD Livers but Seems Less Useful in Standard Heart-Beating Livers: A Comparative Study in a Rat Model
Background: Normothermic oxygenated machine perfusion (NMP) may reduce ischemia/reperfusion (I/R) injury in livers derived from donation after cardiac death (DCD) donors. Aim of this study…2013 American Transplant Congress
Decadal Analysis of Deceased Organ Donation in Spain and the U.S., Linking Increased Donation Rate and Utilization of Older Donors
After founding the Organizacion Nacional de Trasplantes (ONT), Spanish donation rates from deceased donors rapidly outpaced U.S. growth over the decade between 1989-1999. This analysis…2013 American Transplant Congress
New Method of Flow Cytometry Assay of Antibody Binding to Human Renal Microvascular Endothelial Cells, A
Division of Nephrology, University of Washington, Seattle, WA
PURPOSE: We developed a protocol for assessing human kidney biopsies by flow cytometry. Using this technique we asked whether or not antibody bound to microvascular…2013 American Transplant Congress
Heavy Water and Hydrogen Gas Confer Protection Against Hepatic Cold Ischemia and Reperfusion Injury in Isolated Perfused Rat Liver
Purpose The present study was designed to determine whether heavy water containing solution (Dsol) for cold preservation and hydrogen gas for reperfusion conferred protection in…2013 American Transplant Congress
Bortezomib Impacts T-Cell Signaling and Regulatory Pathways
Med. Univ South Carolina, Charleston; Cleveland Clinic, Cleveland; Emory University, Atlanta
Introduction/ Aims: Bortezomib (PS-341), a selective 26S proteasome inhibitor has been used to treat antibody mediated rejection (AMR) among allograft recipients. The efficacy of Bortezomib…2013 American Transplant Congress
Outcomes in Lung Transplantation: The RIFLE Classification Optimizes the Predictive Utility of Post-Transplant Acute Kidney Injury as a Determinant of Early and Late Outcomes
The purpose of this study is to compare two methods of classifying acute kidney injury (AKI), the Risk, Injury, Failure, Loss, End stage (RIFLE) and…2013 American Transplant Congress
Gene Expression Assessment in Kidney Transplant Biopsies To Predict Outcomes in Antibody-Mediated Rejection
Antibody-mediated rejection (ABMR) is a major cause of kidney transplant failure, but the determinants of outcome are poorly defined. We hypothesized that disease activity and…2013 American Transplant Congress
Preexisting Donor Specific Antibody (DSA) with a Negative Flow Crossmatch (FCXM) Should Not Preclude Kidney Transplantation
University of Alabama at Birmingham, Birmingham
Background: DSA is associated with increased risk for acute antibody mediated rejection (AMR). The optimal immunosuppression strategy for FCXM negative (-) DSA positive (+) renal…
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