ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    In Vitro Characterization of Vertebral Bone Marrow Used for Immunomodulation in Hand Transplantation

    N. Yuan, K. Sarkar, M. Lemas, J. Bitzan, J. Sproul, W. Lee, G. Brandacher, D. Cooney

    Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Purpose: Peri-operative cadaveric donor vertebral body bone marrow (VBBM) infusion has shown promising immunomodulatory effects (graft maintenance on low-dose tacrolimus monotherapy) in clinical trials of…
  • 2013 American Transplant Congress

    Rates and Outcomes of Renal Transplantation in Children with Intellectual Disability

    A. Wightman, J. Janosko, B. Young, A. Dick, R. McDonald, P. Healey, J. Smith

    Pediatrics, University of Washington, Seattle; Biostatistics, University of Washington, Seattle; Medicine, University of Washington, Seattle; Transplant Surgery, University of Washington, Seattle

    Background: Limited data exist on renal transplantation in children with intellectual disability (ID). In 2008, UNOS began collecting data on the cognitive and academic level…
  • 2013 American Transplant Congress

    Pre-Liver Transplant (LT) Proteinuria Is Not an Absolute Indication for Simultaneous Liver Kidney Transplantation (SLK)

    H. Wadei, A. Keaveny, M. Mai, B. Rosser, M. Prendergast, K. Oshel, T. Gonwa

    Transplantation, Mayo Clinic, Jacksonville, FL

    LT candidates with proteinuria and renal dysfunction are often considered for SLK. Methods: 39 LT candidates with 24-hr urine protein >150 mg/dl and renal dysfunction…
  • 2013 American Transplant Congress

    Decadal Analysis of Deceased Organ Donation in Spain and the U.S., Linking Increased Donation Rate and Utilization of Older Donors

    J. Halldorson, J. Roberts

    Transplant Surgery, University of California, San Diego, CA; Transplant Surgery, University of California, San Francisco, CA

    After founding the Organizacion Nacional de Trasplantes (ONT), Spanish donation rates from deceased donors rapidly outpaced U.S. growth over the decade between 1989-1999. This analysis…
  • 2013 American Transplant Congress

    New Method of Flow Cytometry Assay of Antibody Binding to Human Renal Microvascular Endothelial Cells, A

    N. Leca, S. Anderson, K. Muczynski

    Division of Nephrology, University of Washington, Seattle, WA

    PURPOSE: We developed a protocol for assessing human kidney biopsies by flow cytometry. Using this technique we asked whether or not antibody bound to microvascular…
  • 2013 American Transplant Congress

    Heavy Water and Hydrogen Gas Confer Protection Against Hepatic Cold Ischemia and Reperfusion Injury in Isolated Perfused Rat Liver

    S. Shimada, M. Fukai, K. Wakayama, K. Yamashita, M. Taniguchi, T. Suzuki, T. Shimamura, T. Kamiyama, H. Furukawa, S. Todo, A. Taketomi

    Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan; Organ Transplantation, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan; Gastroenterological Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

    Purpose The present study was designed to determine whether heavy water containing solution (Dsol) for cold preservation and hydrogen gas for reperfusion conferred protection in…
  • 2013 American Transplant Congress

    Gene Expression Assessment in Kidney Transplant Biopsies To Predict Outcomes in Antibody-Mediated Rejection

    A. Loupy, J. Reeve, J. Chang, L. Hidalgo, D. Vernerey, G. Hill, C. Legendre, P. Halloran

    Hôpital Necker, Paris, France; University of Alberta, Edmonton, Canada; Paris Cardiovascular Research Centre, Paris, France; Hôpital Européen Georges Pompidou, Paris, France

    Antibody-mediated rejection (ABMR) is a major cause of kidney transplant failure, but the determinants of outcome are poorly defined. We hypothesized that disease activity and…
  • 2013 American Transplant Congress

    Preexisting Donor Specific Antibody (DSA) with a Negative Flow Crossmatch (FCXM) Should Not Preclude Kidney Transplantation

    V. Kumar, V. Hauptfeld-Dolejsek, A. Kamal Abdelkader, J. Goodman, J. Locke, R. Gaston

    University of Alabama at Birmingham, Birmingham

    Background: DSA is associated with increased risk for acute antibody mediated rejection (AMR). The optimal immunosuppression strategy for FCXM negative (-) DSA positive (+) renal…
  • 2013 American Transplant Congress

    Optimization of the Coating of Pancreatic Islets with T Regulatory Cells in the Novel Immunoprotective Approach

    K. Golab, S. Kizilel, T. Bal, M. Hara, M. Zielinski, X. Wang, J. Grzanka, L. Wang, O. Cochet, M. Tibudan, P. Witkowski

    Department of Surgery, University of Chicago, Chicago, IL; Department of Chemical and Biological Engineering, College of Engineering, Koc University, Istanbul, Turkey; Department of Medicine, University of Chicago, Chicago, IL

    Aim. T regulatory cells (Tregs) possess immunosuppressive properties and can serve as an effective therapy in transplantation. Recently, we have shown that Tregs can be…
  • 2013 American Transplant Congress

    Tuning the OPTN's KPD Optimization Algorithm To Incentivize Centers To Enter Their "Easy-to-Match" Pairs

    D. Stewart, R. Leishman, E. Sleeman, C. Monstello, G. Lunsford, J. Maghirang, T. Sandholm, S. Gentry, R. Formica, J. Friedewald, K. Andreoni

    UNOS; Carnegie Mellon Univ; Johns Hopkins Univ & USNA; Yale Medical Ctr; Northwestern; Univ of Florida

    Background: Currently, priority points are awarded in the OPTN Kidney Paired Donation Pilot Program's (KPDPP) optimization algorithm as follows: zero mismatch (200 pts), highly sensitized…
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