2013 American Transplant Congress
Dual Nanoporous Encapsulation and Local Exenatide Delivery Improves Islet Viability
The Ohio State University, Columbus, OH
Transplantation of pancreatic islets is recognized as a potential curative therapy for TIDM; however, islets are extremely susceptible to the mechanical, hypoxic and immunologic stresses…2013 American Transplant Congress
Tissue Proteomics Reveals Protein Differences Associated with Allograft Cellular Rejection
Purpose: To investigate protein differences in renal allografts to provide insight into the pathophysiology of cellular rejection. The objective is to determine which proteins are…2013 American Transplant Congress
Impact of Seasonal Influenza Immunization (Influenza+ H1N1) on HLA Antibodies and Kidney Allograft Function
Indiana University School of Medicine, Indianapolis, IN
Seasonal influenza vaccine (influenza + H1N1) is recommended for all solid organ transplant patients. Vaccines have been implicated in changes to HLA antibody profile with…2013 American Transplant Congress
Heavy Water and Hydrogen Gas Confer Protection Against Hepatic Cold Ischemia and Reperfusion Injury in Isolated Perfused Rat Liver
Purpose The present study was designed to determine whether heavy water containing solution (Dsol) for cold preservation and hydrogen gas for reperfusion conferred protection in…2013 American Transplant Congress
Decadal Analysis of Deceased Organ Donation in Spain and the U.S., Linking Increased Donation Rate and Utilization of Older Donors
After founding the Organizacion Nacional de Trasplantes (ONT), Spanish donation rates from deceased donors rapidly outpaced U.S. growth over the decade between 1989-1999. This analysis…2013 American Transplant Congress
New Method of Flow Cytometry Assay of Antibody Binding to Human Renal Microvascular Endothelial Cells, A
Division of Nephrology, University of Washington, Seattle, WA
PURPOSE: We developed a protocol for assessing human kidney biopsies by flow cytometry. Using this technique we asked whether or not antibody bound to microvascular…2013 American Transplant Congress
Gene Expression Assessment in Kidney Transplant Biopsies To Predict Outcomes in Antibody-Mediated Rejection
Antibody-mediated rejection (ABMR) is a major cause of kidney transplant failure, but the determinants of outcome are poorly defined. We hypothesized that disease activity and…2013 American Transplant Congress
Preexisting Donor Specific Antibody (DSA) with a Negative Flow Crossmatch (FCXM) Should Not Preclude Kidney Transplantation
University of Alabama at Birmingham, Birmingham
Background: DSA is associated with increased risk for acute antibody mediated rejection (AMR). The optimal immunosuppression strategy for FCXM negative (-) DSA positive (+) renal…2013 American Transplant Congress
Optimization of the Coating of Pancreatic Islets with T Regulatory Cells in the Novel Immunoprotective Approach
Aim. T regulatory cells (Tregs) possess immunosuppressive properties and can serve as an effective therapy in transplantation. Recently, we have shown that Tregs can be…2013 American Transplant Congress
Tuning the OPTN's KPD Optimization Algorithm To Incentivize Centers To Enter Their "Easy-to-Match" Pairs
Background: Currently, priority points are awarded in the OPTN Kidney Paired Donation Pilot Program's (KPDPP) optimization algorithm as follows: zero mismatch (200 pts), highly sensitized…
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