ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Effectiveness of Rituximab and Intravenous Immunoglobulin for the Treatment of Chronic Antibody Mediated Rejection in Kidney Transplant Recipients

    G. An, B. Chung, C. Park, B. Choi, Y. Kim, C. Yang

    Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Background: Chronic antibody-mediated rejection (CAMR) is an important cause of late allograft dysfunction. But established treatment guidelines for CAMR have not been determined. The aim…
  • 2013 American Transplant Congress

    Total Face and Multi-Organ Procurement from a Brain-Dead Donor: Institutional Experience and Proposed Algorithm

    P. Brazio, B. Bojovic, M. Christy, J. Garcia, E. Brown, S. Bartlett, R. Barth, E. Rodriguez

    Department of Surgery, University of Maryland, Baltimore, MD; Division of Plastic Surgery, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD; Division of Cardiac Surgery, University of Maryland, Baltimore, MD; Division of Transplantation, University of Maryland, Baltimore, MD

    Purpose:A full facial procurement should allow concurrent procurement of all solid organs and ensure their integrity. Procurement of facial vascularized composite allografts (VCA) challenges surgical…
  • 2013 American Transplant Congress

    Association of Pancreas Auto-Antibodies (AA) with Donor Specific Anti-HLA Antibodies (DSA) and Pancreatic Allograft Function

    M. Mujtaba, B. Book, T. Taber, J. Fridell, S. Anand, A. Sharfuddin, M. Yaqub, D. Mishler, E. Wiebke, M. Rigby

    Indiana University School of Medicine, Indianapolis, IN

    In type1 diabetics undergoing pancreas transplant the significance of re-exposure to pancreatic auto-antigens in the context of DSA and new alloimmunity is not well known.Twenty…
  • 2013 American Transplant Congress

    Decadal Analysis of Deceased Organ Donation in Spain and the U.S., Linking Increased Donation Rate and Utilization of Older Donors

    J. Halldorson, J. Roberts

    Transplant Surgery, University of California, San Diego, CA; Transplant Surgery, University of California, San Francisco, CA

    After founding the Organizacion Nacional de Trasplantes (ONT), Spanish donation rates from deceased donors rapidly outpaced U.S. growth over the decade between 1989-1999. This analysis…
  • 2013 American Transplant Congress

    New Method of Flow Cytometry Assay of Antibody Binding to Human Renal Microvascular Endothelial Cells, A

    N. Leca, S. Anderson, K. Muczynski

    Division of Nephrology, University of Washington, Seattle, WA

    PURPOSE: We developed a protocol for assessing human kidney biopsies by flow cytometry. Using this technique we asked whether or not antibody bound to microvascular…
  • 2013 American Transplant Congress

    Heavy Water and Hydrogen Gas Confer Protection Against Hepatic Cold Ischemia and Reperfusion Injury in Isolated Perfused Rat Liver

    S. Shimada, M. Fukai, K. Wakayama, K. Yamashita, M. Taniguchi, T. Suzuki, T. Shimamura, T. Kamiyama, H. Furukawa, S. Todo, A. Taketomi

    Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan; Organ Transplantation, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan; Gastroenterological Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

    Purpose The present study was designed to determine whether heavy water containing solution (Dsol) for cold preservation and hydrogen gas for reperfusion conferred protection in…
  • 2013 American Transplant Congress

    Tuning the OPTN's KPD Optimization Algorithm To Incentivize Centers To Enter Their "Easy-to-Match" Pairs

    D. Stewart, R. Leishman, E. Sleeman, C. Monstello, G. Lunsford, J. Maghirang, T. Sandholm, S. Gentry, R. Formica, J. Friedewald, K. Andreoni

    UNOS; Carnegie Mellon Univ; Johns Hopkins Univ & USNA; Yale Medical Ctr; Northwestern; Univ of Florida

    Background: Currently, priority points are awarded in the OPTN Kidney Paired Donation Pilot Program's (KPDPP) optimization algorithm as follows: zero mismatch (200 pts), highly sensitized…
  • 2013 American Transplant Congress

    Viral Determinants of Pathogen Induced Alloantibody Production

    R. Ruhil, O. Bulut, S. Talebagha, B. Oh, V. Lu, S. Knechtle, N. Iwakoshi

    Emory Transplant Center, Atlanta

    Background: The appearance of alloantibody can initiate the onset of rapid and destructive antibody-mediated rejection (AMR) or have no demonstrable acute effects. The factors determining…
  • 2013 American Transplant Congress

    CMV Serostatus Correlation with Early Kidney Allograft Transcriptome Change in the GOCAR Cohort

    A. Le Page, W. Zhang, B. Murphy, B. Nankivell, J. Chapman, P. O'Connell, S. Alexander, W. Rawlinson

    University of NSW, Randwick, Australia; Mt Sinai School of Medicine, New York; Westmead Hospital, Westmead, Australia; The Children's Hospital Westmead, Westmead, Australia

    Identifying transcriptional change in renal allografts infected with Cytomegalovirus (CMV) may be important in understanding CMV effects on graft rejection and injury.We examined transcriptional profiles…
  • 2013 American Transplant Congress

    Late Antibody-Mediated Rejection (AMR) after Kidney Transplantation

    M. Martina, F. Oppenheimer, I. Revuelta, J. Campistol Planas, M. Sole, J. Cid, F. Diekmann

    Nephrology, Hospital Clinic, Barcelona, Spain; Hematology, Hospital Clinic, Barcelona, Spain; Pathology, Hospital Clinic, Barcelona, Spain

    INTRODUCTION: Late AMR can develop at any time post kidney transplantation and represents a major challenge.OBJECTIVE: To characterize a series of kidney transplant recipients with…
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