2013 American Transplant Congress
Effectiveness of Rituximab and Intravenous Immunoglobulin for the Treatment of Chronic Antibody Mediated Rejection in Kidney Transplant Recipients
Background: Chronic antibody-mediated rejection (CAMR) is an important cause of late allograft dysfunction. But established treatment guidelines for CAMR have not been determined. The aim…2013 American Transplant Congress
Total Face and Multi-Organ Procurement from a Brain-Dead Donor: Institutional Experience and Proposed Algorithm
Purpose:A full facial procurement should allow concurrent procurement of all solid organs and ensure their integrity. Procurement of facial vascularized composite allografts (VCA) challenges surgical…2013 American Transplant Congress
Association of Pancreas Auto-Antibodies (AA) with Donor Specific Anti-HLA Antibodies (DSA) and Pancreatic Allograft Function
Indiana University School of Medicine, Indianapolis, IN
In type1 diabetics undergoing pancreas transplant the significance of re-exposure to pancreatic auto-antigens in the context of DSA and new alloimmunity is not well known.Twenty…2013 American Transplant Congress
mTOR Inhibition Blocks CCR9 Upregulation Induced by All-Trans Retinoic Acid in Naturally-Occurring CD4+ FoxP3+ Regulatory T Cells
BackgroundCD4+ FoxP3+ regulatory T cells (Treg) are an important population of suppressor T cells that have shown promise in treating experimental autoimmune disease, allograft rejection,…2013 American Transplant Congress
Organ Procurement and Transplantation Network (OPTN) Kidney Paired Donation Pilot Program (KPDPP): Review of Current Results, The
UNOS; Yale Medical Ctr; Univ of Florida; Northwestern Univ; Carnegie Mellon Univ
Background: On Oct 27, 2010, the OPTN KPDPP ran its first of 40 match runs. 128 transplant centers representing all 11 regions have joined, with…2013 American Transplant Congress
Genome-Wide Chromatin Remodeling by the Transcription Factor Foxp3
Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA
Foxp3 is a transcription factor expressed by a subset of lymphocytes called regulatory T cells (Treg). Unlike conventional T cells that mediate immunity, Treg suppress…2013 American Transplant Congress
Identification of Independent Risk Factors for De Novo DSA Development through Prospective Monitoring
The Methodist Hospital, Houston, TX
Background: Donor specific anti-human leukocyte antigen (HLA) antibodies (DSA) after renal transplant have been associated with poor outcomes in the form of renal dysfunction, increased…2013 American Transplant Congress
Chronic Opioid Usage Early after Kidney Transplantation
Introduction: Chronic opioids usage (COU) is common among patients with end stage renal disease (ESRD) receiving dialysis treatment and associated with poor clinical outcomes. We…2013 American Transplant Congress
Normothermic Oxygenated Machine Preservation Reduces Reperfusion Injury of DCD Livers but Seems Less Useful in Standard Heart-Beating Livers: A Comparative Study in a Rat Model
Background: Normothermic oxygenated machine perfusion (NMP) may reduce ischemia/reperfusion (I/R) injury in livers derived from donation after cardiac death (DCD) donors. Aim of this study…2013 American Transplant Congress
Removal of CD39+ T Cells Uncovers a Population of Col V Specific, CD39- Responder T Cells in Normal, Healthy Individuals
Transplant Surgery, University of Wisconsin, Madison, WI
We and others have reported that autoimmunity to the self antigen Collagen V (ColV) after lung transplantation, is strongly correlated with the development of Bronchiolitis…
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