ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Tissue Proteomics Reveals Protein Differences Associated with Allograft Cellular Rejection

    M. Talwar, V. Ahmed, T. Srinivas, N. Bhensdadia, B. Alison, J. Alge, S. Self, J. Arthur, M. Janech

    Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, SC; Department of Pathology, Medical University of South Carolina, Charleston, SC

    Purpose: To investigate protein differences in renal allografts to provide insight into the pathophysiology of cellular rejection. The objective is to determine which proteins are…
  • 2013 American Transplant Congress

    Impact of Seasonal Influenza Immunization (Influenza+ H1N1) on HLA Antibodies and Kidney Allograft Function

    M. Mujtaba, M. Urabi, A. Sanjiv, A. Sharfuddin, N. Higgins, S. Faiz, M. Yaqub, D. Mishler, A. Lobashevsky, T. Taber

    Indiana University School of Medicine, Indianapolis, IN

    Seasonal influenza vaccine (influenza + H1N1) is recommended for all solid organ transplant patients. Vaccines have been implicated in changes to HLA antibody profile with…
  • 2013 American Transplant Congress

    Medical Nonadherence as a Cause of Renal Allograft Failure: A Ten Year Single Center Retrospective Analysis

    B. Fischbach, S. Gonzalez, A. Yango, A. Chandrakantan, L. Melton, A. Rajagopal, Y. Barri, K. Rice, J. DiNubila, M. Levy, G. Klintmalm

    Annette C & Harold C Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    Background: Despite the advent of modern immunosuppression, long term renal allograft outcomes have remained relatively unchanged. In the renal transplant population, medical nonadherence is a…
  • 2013 American Transplant Congress

    Drop in Allograft Function Associates with Drop in Bone Mineral Density Z Score in Pediatric Renal Transplant Recipients

    E. Anyaegbu, J. Zheng, V. Dharnidharka

    Washington University in St Louis School of Medicine, St Louis, MO

    The high prevalence of renal osteodystrophy (ROD) in pediatric renal transplant recipients has been linked to the duration of dialysis pre transplant, exposure to steroids,…
  • 2013 American Transplant Congress

    Role of PI3K/AKT and Autophagy in the Protective Effect of Fasting Against Liver Ischemia Reperfusion Injury in Mice, The

    G. Li, J. Rao, J. Qin, L. Lu, X. Wang

    Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    Background and aim: Preoperative fasting is known to attenuate liver ischemia reperfusion injury (IRI). However, the exact mechanism behind this protective effect is unknown. This…
  • 2013 American Transplant Congress

    Utilization of the Chronic Kidney Disease-EPI Equation To Predict Outcomes in Lung Transplant Recipients

    A. Osho, A. Castleberry, L. Snyder, S. Palmer, S. Lin, R. Davis, M. Hartwig

    Department of Surgery, Duke University Medical Center, Durham, NC; Department of Medicine, Duke University Medical Center, Durham, NC

    The purpose of this study is to compare two formulas for GFR estimation – the popular Modified Diet in Renal Disease, MDRD and the recently…
  • 2013 American Transplant Congress

    In Vitro Characterization of Vertebral Bone Marrow Used for Immunomodulation in Hand Transplantation

    N. Yuan, K. Sarkar, M. Lemas, J. Bitzan, J. Sproul, W. Lee, G. Brandacher, D. Cooney

    Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Purpose: Peri-operative cadaveric donor vertebral body bone marrow (VBBM) infusion has shown promising immunomodulatory effects (graft maintenance on low-dose tacrolimus monotherapy) in clinical trials of…
  • 2013 American Transplant Congress

    Rates and Outcomes of Renal Transplantation in Children with Intellectual Disability

    A. Wightman, J. Janosko, B. Young, A. Dick, R. McDonald, P. Healey, J. Smith

    Pediatrics, University of Washington, Seattle; Biostatistics, University of Washington, Seattle; Medicine, University of Washington, Seattle; Transplant Surgery, University of Washington, Seattle

    Background: Limited data exist on renal transplantation in children with intellectual disability (ID). In 2008, UNOS began collecting data on the cognitive and academic level…
  • 2013 American Transplant Congress

    Pre-Liver Transplant (LT) Proteinuria Is Not an Absolute Indication for Simultaneous Liver Kidney Transplantation (SLK)

    H. Wadei, A. Keaveny, M. Mai, B. Rosser, M. Prendergast, K. Oshel, T. Gonwa

    Transplantation, Mayo Clinic, Jacksonville, FL

    LT candidates with proteinuria and renal dysfunction are often considered for SLK. Methods: 39 LT candidates with 24-hr urine protein >150 mg/dl and renal dysfunction…
  • 2013 American Transplant Congress

    Regulatory Dendritic Cells (DCreg) Prolong Kidney Allograft Survival in Non-Human Primates When Combined with Costimulation Blockade and Rapamycin

    M. Ezzelarab, A. Zahorchak, L. Lu, M. Adrian, L. Fadi, J. Demetris, A. Humar, R. Shapiro, N. Murase, M. Wijkstrom, D. Cooper, A. Thomson

    Surgery, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Immunology, University of Pittsburgh, Pittsburgh, PA; University of Pittsburgh, Pittsburgh, PA

    Background: Regulatory immune cells are promising therapeutic agents to promote immunosuppressive drug minimization/withdrawal in organ transplantation. Dendritic cells (DC) are innate immune antigen (Ag)-presenting cells…
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