ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Recipient Pre-Operative Regulatory T Cell Function: A Predictor of Acute Kidney Injury after Kidney Transplantation

    M. Nguyen, S. Sahakian, E. Fryml, M. Cantarovich, S. Liu, M. Lipman, J. Tchervenkov, S. Paraskevas

    Multi-Organ Transplant Program, McGill University Health Centre, Montreal, QC, Canada

    Background: Acute kidney injury (AKI), in both its most severe (delayed graft function, DGF) and milder (slow graft function, SGF) forms, increases the risk for…
  • 2013 American Transplant Congress

    Loss of Pediatric Kidney Grafts during the "High-Risk Age Window": Insights from Liver Recipients

    K. Van Arendonk, B. Orandi, B. Boyarsky, N. James, P. Colombani, J. Magee, D. Segev

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Surgery, University of Michigan Medical School, Ann Arbor, MI

    Background. Pediatric kidney recipients must traverse a high-risk age window of late adolescence and early adulthood during which there is an increased risk of graft…
  • 2013 American Transplant Congress

    Use of the Flotrac System To Guide Donor Management Is Associated with Increased Organs Transplanted Per Donor, The

    B. Bergstrom, S. Louis, F. Peterson, H. Aguiar, M. Friedman, D. Malinoski

    Donor Network of Arizona, Phoenix, AZ; Portland VA Medical Center, Portland, OR; OneLegacy, Los Angeles, CA

    INTRODUCTION: There is a national shortage of organs available for transplantation and utilization rates for thoracic organs are less than 40%. The management of organ…
  • 2013 American Transplant Congress

    Effectiveness of Rituximab and Intravenous Immunoglobulin for the Treatment of Chronic Antibody Mediated Rejection in Kidney Transplant Recipients

    G. An, B. Chung, C. Park, B. Choi, Y. Kim, C. Yang

    Transplant Research Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

    Background: Chronic antibody-mediated rejection (CAMR) is an important cause of late allograft dysfunction. But established treatment guidelines for CAMR have not been determined. The aim…
  • 2013 American Transplant Congress

    Total Face and Multi-Organ Procurement from a Brain-Dead Donor: Institutional Experience and Proposed Algorithm

    P. Brazio, B. Bojovic, M. Christy, J. Garcia, E. Brown, S. Bartlett, R. Barth, E. Rodriguez

    Department of Surgery, University of Maryland, Baltimore, MD; Division of Plastic Surgery, R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, MD; Division of Cardiac Surgery, University of Maryland, Baltimore, MD; Division of Transplantation, University of Maryland, Baltimore, MD

    Purpose:A full facial procurement should allow concurrent procurement of all solid organs and ensure their integrity. Procurement of facial vascularized composite allografts (VCA) challenges surgical…
  • 2013 American Transplant Congress

    Association of Pancreas Auto-Antibodies (AA) with Donor Specific Anti-HLA Antibodies (DSA) and Pancreatic Allograft Function

    M. Mujtaba, B. Book, T. Taber, J. Fridell, S. Anand, A. Sharfuddin, M. Yaqub, D. Mishler, E. Wiebke, M. Rigby

    Indiana University School of Medicine, Indianapolis, IN

    In type1 diabetics undergoing pancreas transplant the significance of re-exposure to pancreatic auto-antigens in the context of DSA and new alloimmunity is not well known.Twenty…
  • 2013 American Transplant Congress

    mTOR Inhibition Blocks CCR9 Upregulation Induced by All-Trans Retinoic Acid in Naturally-Occurring CD4+ FoxP3+ Regulatory T Cells

    L. Chen, A. Thomson, G. Raimondi

    Immunology and Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA

    BackgroundCD4+ FoxP3+ regulatory T cells (Treg) are an important population of suppressor T cells that have shown promise in treating experimental autoimmune disease, allograft rejection,…
  • 2013 American Transplant Congress

    Organ Procurement and Transplantation Network (OPTN) Kidney Paired Donation Pilot Program (KPDPP): Review of Current Results, The

    R. Leishman, R. Formica, K. Andreoni, J. Friedewald, E. Sleeman, C. Monstello, D. Stewart, T. Sandholm

    UNOS; Yale Medical Ctr; Univ of Florida; Northwestern Univ; Carnegie Mellon Univ

    Background: On Oct 27, 2010, the OPTN KPDPP ran its first of 40 match runs. 128 transplant centers representing all 11 regions have joined, with…
  • 2013 American Transplant Congress

    Genome-Wide Chromatin Remodeling by the Transcription Factor Foxp3

    C. Chen, Z. Zhang, M. Johnson, A. Wells

    Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

    Foxp3 is a transcription factor expressed by a subset of lymphocytes called regulatory T cells (Treg). Unlike conventional T cells that mediate immunity, Treg suppress…
  • 2013 American Transplant Congress

    Identification of Independent Risk Factors for De Novo DSA Development through Prospective Monitoring

    J. DeVos, R. Knight, S. Patel, G. Land, E. Graviss, L. Teeter, A. Gaber

    The Methodist Hospital, Houston, TX

    Background: Donor specific anti-human leukocyte antigen (HLA) antibodies (DSA) after renal transplant have been associated with poor outcomes in the form of renal dysfunction, increased…
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