ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Role of PI3K/AKT and Autophagy in the Protective Effect of Fasting Against Liver Ischemia Reperfusion Injury in Mice, The

    G. Li, J. Rao, J. Qin, L. Lu, X. Wang

    Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    Background and aim: Preoperative fasting is known to attenuate liver ischemia reperfusion injury (IRI). However, the exact mechanism behind this protective effect is unknown. This…
  • 2013 American Transplant Congress

    Utilization of the Chronic Kidney Disease-EPI Equation To Predict Outcomes in Lung Transplant Recipients

    A. Osho, A. Castleberry, L. Snyder, S. Palmer, S. Lin, R. Davis, M. Hartwig

    Department of Surgery, Duke University Medical Center, Durham, NC; Department of Medicine, Duke University Medical Center, Durham, NC

    The purpose of this study is to compare two formulas for GFR estimation – the popular Modified Diet in Renal Disease, MDRD and the recently…
  • 2013 American Transplant Congress

    In Vitro Characterization of Vertebral Bone Marrow Used for Immunomodulation in Hand Transplantation

    N. Yuan, K. Sarkar, M. Lemas, J. Bitzan, J. Sproul, W. Lee, G. Brandacher, D. Cooney

    Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Purpose: Peri-operative cadaveric donor vertebral body bone marrow (VBBM) infusion has shown promising immunomodulatory effects (graft maintenance on low-dose tacrolimus monotherapy) in clinical trials of…
  • 2013 American Transplant Congress

    Rates and Outcomes of Renal Transplantation in Children with Intellectual Disability

    A. Wightman, J. Janosko, B. Young, A. Dick, R. McDonald, P. Healey, J. Smith

    Pediatrics, University of Washington, Seattle; Biostatistics, University of Washington, Seattle; Medicine, University of Washington, Seattle; Transplant Surgery, University of Washington, Seattle

    Background: Limited data exist on renal transplantation in children with intellectual disability (ID). In 2008, UNOS began collecting data on the cognitive and academic level…
  • 2013 American Transplant Congress

    Pre-Liver Transplant (LT) Proteinuria Is Not an Absolute Indication for Simultaneous Liver Kidney Transplantation (SLK)

    H. Wadei, A. Keaveny, M. Mai, B. Rosser, M. Prendergast, K. Oshel, T. Gonwa

    Transplantation, Mayo Clinic, Jacksonville, FL

    LT candidates with proteinuria and renal dysfunction are often considered for SLK. Methods: 39 LT candidates with 24-hr urine protein >150 mg/dl and renal dysfunction…
  • 2013 American Transplant Congress

    Regulatory Dendritic Cells (DCreg) Prolong Kidney Allograft Survival in Non-Human Primates When Combined with Costimulation Blockade and Rapamycin

    M. Ezzelarab, A. Zahorchak, L. Lu, M. Adrian, L. Fadi, J. Demetris, A. Humar, R. Shapiro, N. Murase, M. Wijkstrom, D. Cooper, A. Thomson

    Surgery, Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; Immunology, University of Pittsburgh, Pittsburgh, PA; University of Pittsburgh, Pittsburgh, PA

    Background: Regulatory immune cells are promising therapeutic agents to promote immunosuppressive drug minimization/withdrawal in organ transplantation. Dendritic cells (DC) are innate immune antigen (Ag)-presenting cells…
  • 2013 American Transplant Congress

    Cause of Progression in Failing Kidney Transplants with Diseases Is Parenchymal Injury, Not Fibrosis, The

    K. Famulski, J. Revee, P. Halloran

    Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada

    We previously reported that human kidney transplants with early acute kidney injury (AKI) biopsied in the first six weeks express transcripts indicating injury-repair (IRRATs). Expression…
  • 2013 American Transplant Congress

    Recipient Pre-Operative Regulatory T Cell Function: A Predictor of Acute Kidney Injury after Kidney Transplantation

    M. Nguyen, S. Sahakian, E. Fryml, M. Cantarovich, S. Liu, M. Lipman, J. Tchervenkov, S. Paraskevas

    Multi-Organ Transplant Program, McGill University Health Centre, Montreal, QC, Canada

    Background: Acute kidney injury (AKI), in both its most severe (delayed graft function, DGF) and milder (slow graft function, SGF) forms, increases the risk for…
  • 2013 American Transplant Congress

    Loss of Pediatric Kidney Grafts during the "High-Risk Age Window": Insights from Liver Recipients

    K. Van Arendonk, B. Orandi, B. Boyarsky, N. James, P. Colombani, J. Magee, D. Segev

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Surgery, University of Michigan Medical School, Ann Arbor, MI

    Background. Pediatric kidney recipients must traverse a high-risk age window of late adolescence and early adulthood during which there is an increased risk of graft…
  • 2013 American Transplant Congress

    Use of the Flotrac System To Guide Donor Management Is Associated with Increased Organs Transplanted Per Donor, The

    B. Bergstrom, S. Louis, F. Peterson, H. Aguiar, M. Friedman, D. Malinoski

    Donor Network of Arizona, Phoenix, AZ; Portland VA Medical Center, Portland, OR; OneLegacy, Los Angeles, CA

    INTRODUCTION: There is a national shortage of organs available for transplantation and utilization rates for thoracic organs are less than 40%. The management of organ…
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