2013 American Transplant Congress
Subclinical EBV and CMV Viremia Is Significantly Associated with the Development of Interstitial Fibrosis and Tubular Atrophy (IF/TA) in Pediatric Renal Transplant Recipients
Purpose:The leading cause of pediatric kidney transplant loss is chronic renal allograft dysfunction (CRAD). Currently, the etiology of CRAD is thought to be multi-factorial. While…2013 American Transplant Congress
Early Emergence of De Novo Donor-Specific Antibody Is Associated with High Incidence of Acute Rejection in Kidney Transplant Recipients
University of Michigan, Ann Arbor, MI
Purpose: De novo HLA donor-specific antibodies (dnDSA) is common in chronic renal allograft rejection. However, the significance of dnDSA is less clear in the early…2013 American Transplant Congress
Impact of Donor Hypoxemia and Hypotension in DCD Liver Transplantation
Medstar Georgetown University Hospital, Washington, DC
Aim: Donation after cardiac death (DCD) is a valuable source of liver grafts Little is known about the impact of severe hypoxemia and hypotension before…2013 American Transplant Congress
Understanding Racial Disparity in Living Donor Kidney Transplantation
Division of Transplantation, University of Illinois at Chicago, CHicago, IL
BACKGROUND: There is a large ethnical disparity in the rate of living kidney donation. We analyzed possible causes of this difference.METHOD: We performed a single-center…2013 American Transplant Congress
Levels of IL-33 and Soluble IL-33 Receptor (sST2) Distinguish Acute Rejection from Enteritis in Small Bowel Transplant Recipients
BackgroundIL-33 is a member of the IL-1 cytokine family with functions ascribed to its actions on immune cells expressing the IL-33 receptor, ST2. Following heart…2013 American Transplant Congress
Incorporating Time from Donation (TFD) to the MDRD and CKD-EPI Formulas Enhances Their Performance in Kidney Donors
Introduction:The reexpressed MDRD study equation is least biased in estimating GFR in former kidney donors. Hyperfiltration is not limited to the first year after donation.…2013 American Transplant Congress
In Vivo Interaction between ATG and IVIg May Decrease the Efficacy of Antibody Mediated Rejection Treatment
Treatment of antibody mediated rejection(AMR) is not standardized. Anti-thymocyte globulin(ATG) is commonly used in combination with intravenous immunoglobulin(IVIg) and plasmapheresis(Px). Our in vitro data show…2013 American Transplant Congress
New OPTN Requirement for DNA-Based HLA Typing for Deceased Donors: Initial Results Show Increased Typing Resolution for Improving Virtual Crossmatches, A
UCSF, San Francisco, CA; UNOS, Richmond, VA; Cedars-Sinai, Los Angeles, CA
Historically HLA typing of deceased donors was performed using serological or DNA-based methods. On 6/1/11, the Organ Procurement and Transplantation Network (OPTN) implemented a new…2013 American Transplant Congress
mTOR Inhibition Blocks CCR9 Upregulation Induced by All-Trans Retinoic Acid in Naturally-Occurring CD4+ FoxP3+ Regulatory T Cells
BackgroundCD4+ FoxP3+ regulatory T cells (Treg) are an important population of suppressor T cells that have shown promise in treating experimental autoimmune disease, allograft rejection,…2013 American Transplant Congress
Organ Procurement and Transplantation Network (OPTN) Kidney Paired Donation Pilot Program (KPDPP): Review of Current Results, The
UNOS; Yale Medical Ctr; Univ of Florida; Northwestern Univ; Carnegie Mellon Univ
Background: On Oct 27, 2010, the OPTN KPDPP ran its first of 40 match runs. 128 transplant centers representing all 11 regions have joined, with…
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