2013 American Transplant Congress
Neuropeptide PACAP Mediated Autophagy in Mouse Liver Ischemia and Reperfusion Injury: Modulation Via cAMP/PKA-CREB-KLF4 Pathway
Dept of Surgery, Dumont-UCLA Liver Transplant Center, Los Angeles, CA
Background: Autophagy (‘self-eating’) represents a critical mechanism for cellular homeostasis and survival response to the stress. We have shown that neuropeptide PACAP (Pituitary Adenylate Cyclase-Activating…2013 American Transplant Congress
Sensitivity of Screening Echocardiogram to Detected Pulmonary Hypertension in Patients with End Stage Liver Disease Undergoing Liver Transplant Evaluation
Background: The presence of pulmonary hypertension (PHTN) in the setting of end stage liver disease increases mortality before and after orthotopic liver transplantation (OLT). A…2013 American Transplant Congress
Clinical Significance of Protocol Biopsy at Three Months after Kidney Transplantation: A Single Center Experience
The aim of this study was to analyze the characteristics of subclinical acute rejection and borderline change in protocol biopsies performed 3 months after kidney…2013 American Transplant Congress
Steroid Avoidance with Alemtuzumab Induction and Tacrolimus Monotherapy Gives Similar Outcomes to Basiliximab Induction with Tacrolimus / Mycophenolate Maintenance at Three Years
A randomised controlled trial comparing two steroid avoidance regimes was conducted in our centre from December 2006 to November 2010. Alemtuzumab induction followed by tacrolimus…2013 American Transplant Congress
TCMR Is Underdiagnosed in BK Virus Nephropathy: A Tale of 2 Populations
BK virus nephropathy (BKN) after kidney transplantation is often associated with TCMR-like histology, but pathologists are uncertain about whether this is TCMR. We studied the…2013 American Transplant Congress
Identifying the Most Dangerous DSA: A 12-Year Longitudinal Post-Transplant Study of IgM, IgG, and IgG Isotype HLA Alloantibodies in Primary Renal Transplant Recipients
Due to the lack of longitudinal serum collection in transplant patients, the natural history of the humoral response is undocumented and may reveal why many…2013 American Transplant Congress
Subclinical EBV and CMV Viremia Is Significantly Associated with the Development of Interstitial Fibrosis and Tubular Atrophy (IF/TA) in Pediatric Renal Transplant Recipients
Purpose:The leading cause of pediatric kidney transplant loss is chronic renal allograft dysfunction (CRAD). Currently, the etiology of CRAD is thought to be multi-factorial. While…2013 American Transplant Congress
Early Emergence of De Novo Donor-Specific Antibody Is Associated with High Incidence of Acute Rejection in Kidney Transplant Recipients
University of Michigan, Ann Arbor, MI
Purpose: De novo HLA donor-specific antibodies (dnDSA) is common in chronic renal allograft rejection. However, the significance of dnDSA is less clear in the early…2013 American Transplant Congress
Impact of Donor Hypoxemia and Hypotension in DCD Liver Transplantation
Medstar Georgetown University Hospital, Washington, DC
Aim: Donation after cardiac death (DCD) is a valuable source of liver grafts Little is known about the impact of severe hypoxemia and hypotension before…2013 American Transplant Congress
Understanding Racial Disparity in Living Donor Kidney Transplantation
Division of Transplantation, University of Illinois at Chicago, CHicago, IL
BACKGROUND: There is a large ethnical disparity in the rate of living kidney donation. We analyzed possible causes of this difference.METHOD: We performed a single-center…
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