2013 American Transplant Congress
PI3Kδ Inhibition Augments the Efficacy of mTOR Inhibitor Rapamycin on the Proliferation of Epstein-Barr Virus (EBV)+ B Cell Lymphomas
Department of Surgery, Stanford University School of Medicine, Stanford, CA
Post-transplant lymphoproliferative disorder (PTLD) is a devastating and potentially life-threatening complication in transplant recipients. PTLD is associated with EBV infection and can result in malignant…2013 American Transplant Congress
Identification of EBV-Specific CXCR3+/CXCR5+ CD8+T Cells in Peripheral Blood of Asymptomatic Pediatric Heart Transplant Recipients Who Carry EBV Loads
Unlike immunocompetent healthy subjects who carry EBV infection in a latent form, approximately 70% of EBV asymptomatic immunosuppressed pediatric heart transplant (HTx) recipients carry chronic…2013 American Transplant Congress
Safety Risks in Living Donor Liver Transplantation
OBJECTIVE/BACKGROUND:According to the 2010 U.S. Office of the Inspector General’s Report, adverse events (AE) are common in the care of patients. In Living Donor Liver…2013 American Transplant Congress
Three Genotypically Distinct Strains of Pneumocystis Jirovecii Caused an Outbreak of Pneumocystis Pneumonia in Renal and Liver Transplant Recipients
Background: Pneumocystis jirovecii pneumonia (PCP) is a serious and possibly lethal opportunistic infection in immunocompromised patients. An outbreak of 29 PCP cases occurred among renal…2013 American Transplant Congress
Time on Waiting List for Patients with High MELD Does Not Influence Graft or Patient Survival after Liver Transplantation
Northwestern University, Chicago
BACKGROUND: With the decreased donor availability, even patients with high MELD scores can have prolonged wait times for liver transplantation (LT). However, it is unknown…2013 American Transplant Congress
Injected Allogeneic CD4+CD25+ Tregs Regulate the Neonatal Immune System and Prolong Heart Allograft Survival
University of Alberta, Edmonton, Canada
Introduction/Methods: Semi-allogeneic (F1; H-2k/b) splenocytes (SC) injected into newborn mice (H-2k) induce immunological tolerance whereas allogeneic SC (H-2b) lead to graft-vs-host disease (GVHD). Here we…2013 American Transplant Congress
Obesity Negatively Impacts Access to Transplantation in Women but Not Men
Nephrology, University of British Columbia, Vancouver, Canada
It is known that obese wait-listed patients are less likely to undergo deceased donor transplantation compared to non-obese patients. Using Cox multivariate regression analyses and…2013 American Transplant Congress
Mismatched VCA Transplantation without the Need for Donor Cell Chimerism: A Model To Achieve Tolerance While Eliminating Chronic Immunosuppression and the Risks of GVHD
Introduction: The application of Vascularized Composite Allograft (VCA) transplantation is limited by the need for immunosuppression. Tolerance induction protocols using stem cell transplantation can eliminate…2013 American Transplant Congress
Rationale for, and the Economic Implications Associated with, Extending Medicare Coverage for Immunosuppressive Medications to Kidney Transplant Recipients Who Lack Insurance Coverage, The
United Network for the Recruitment of Transplantation Professionals, Rochester, MN
Immunosuppressive medications are essential in preventing kidney transplant rejection. Continuous insurance coverage for outpatient immunosuppressive medications remains a major issue. The objective of this analysis…2013 American Transplant Congress
Uniform Long-Term Graft Survival in a Clincial Trial of the Induction of Tolerance to Kidney Transplants
Stanford University, Stanford, CA
Purpose: Over the last 12 years we have studied the safety and efficacy of a clinical tolerance induction protocol using hematopoietic cell transplantation in combination…
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