Am J Transplant, Volume 20, Suppl 3 Archives - Page 85 of 223 - ATC Abstracts

2020 American Transplant Congress
Selectively Transplanting Moderately to Severely Macrosteatotic Grafts: Does Recipient Metabolic Environment Affect Outcomes?
P. J. Altshuler, A. Rios Diaz, O. Shaheen, A. P. Shah, W. R. Maley, A. Frank, C. Ramirez, J. Glorioso, H. Dang, A. S. Bodzin
Department of Surgery, Thomas Jefferson University, Philadelphia, PA
*Purpose: As incidence of Non-Alcoholic Steatohepatitis (NASH) cirrhosis rises, organ utilization remains stagnant. Recently, it has been shown that selective utilization of >30% macrosteatotic grafts…
2020 American Transplant Congress
Stewardship Effortsto Eliminate Post-Orthotopic Liver Transplant Antibiotics in Uncomplicated Patients Leads to Equivalent Safety Outcomes
J. Yau, J. Dann, W. Ally, J. Geyston, S. Pelletier, C. Sifri
University of Virginia Health System, Charlottesville, VA
*Purpose: The purpose of this study was to evaluate safety and efficacy endpoints of a revised post-operative antibiotic prophylaxis protocol in orthotopic liver transplant (OLT)…
2020 American Transplant Congress
Computer-Assisted Cardiac Histologic Evaluation (CACHE) for Grading Cardiac Allograft Rejection
E. Peyster¹, S. ArabYarmohommadi², A. Janowczyk², M. Sekulic³, C. Cassol⁴, M. Feldman¹, K. Margulies¹, A. Madabhushi²
¹University of Pennsylvania, Philadelphia, PA, ²Case Western Reserve University, Cleveland, OH, ³University Hospitals Cleveland Medical Center, Cleveland, OH, ⁴Ohio State University, Columbus, OH
*Purpose: Cardiac allograft rejection (CAR) is a serious concern in heart transplantation, occurring in 30-40% of patients during the first year. Endomyocardial biopsy (EMB) with…
2020 American Transplant Congress
Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection
R. El Fekih¹, A. Alghamdi¹, J. Hurley², C. Coticchia², J. Choi¹, H. Allos¹, S. Eskandari¹, S. Bentink², V. Tadigotla², L. Riella¹, J. Markmann³, K. Safa³, R. Formica⁴, J. Skog², J. Azzi¹
¹Medecine, Brigham and Women's Hospital, Boston, MA, ²Exosome Diagnostics Inc., Waltham, MA, ³Massachusetts General Hospital, Boston, MA, ⁴Yale School of Medecine, New Haven, CT
*Purpose: Monitoring kidney transplant rejection by repeated biopsies might result in increased procedural complications and cost. Exosomes are nanometer-sized vesicles released by cells carrying trans…
2020 American Transplant Congress
Calculated Panel Reactive Antibody Values Increase for Kidney Transplant Candidates with HLA-DQA and HLA-DPB Unacceptable Antigens
E. P. Kransdorf¹, C. Murphey², M. Maiers³, L. Gragert⁴
¹Cedars-Sinai Heart Institute, Beverly Hills, CA, ²Immunogenetics Lab, Southwest Immunodiagnostics, Inc., San Antonio, TX, ³Bioinformatics Research, Be The Match/National Marrow Donor Program, Minneapolis, MN, ⁴Department of Pathology, Tulane University School of Medicine, New Orleans, LA
*Purpose: Calculated panel-reactive antibody (CPRA) is the official metric of sensitization used by the United Network for Organ Sharing (UNOS) for kidney allocation. CPRA includes…
2020 American Transplant Congress
Use of Sitagliptin versus Placebo to Reduce the Incidence and Severity of Post-Transplant Diabetes after Kidney Transplantation
H. Wijeweera, J. Hagopian, M. Ramakrishnan, L. Chen, R. Delos Santos
Washington University in St. Louis, Saint Louis, MO
*Purpose: Post-transplant diabetes mellitus (PTDM) is a complication in non-diabetic kidney transplant (KT) recipients due weight gain and use of CNI and corticosteroids in immunosuppression…
2020 American Transplant Congress
Outcomes and Experience with Belatacept in Pediatric Kidney Transplantation
R. Garro¹, P. Winterberg¹, R. Liverman², A. Serluco², B. Warshaw¹, R. George¹
¹Emory University, Atlanta, GA, ²Children's Healthcare of Atlanta, Atlanta, GA
*Purpose: Belatacept is a selective co-stimulation blocker used in adult renal transplantation and has shown improvement in glomerular filtration rate (GFR) compared to calcineurin inhibitors…
2020 American Transplant Congress
Functional Changes in Metabolic and Malignancy Associated Bacterial Genes in the Post Transplant Intestinal Microbiome
M. Bhat¹, S. Sivaraj¹, E. Pasini¹, J. Copeland², J. Allard³, A. Humar¹
¹Multi-Organ Transplant, UHN, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³UHN, Toronto, ON, Canada
*Purpose: Long-term survival of liver transplant (LT) recipients is affected by metabolic and malignant complications. The aim of our study was to examine changes in…
2020 American Transplant Congress
Assessing Interventions to Improve Patient Care Conducted by Pharmacists at an Outpatient Renal Transplant Clinic within a Collaborative Pharmacy Practice Agreement
K. Johnson, R. Chelewski, A. Langone, M. Peter, A. Zuckerman
Vanderbilt University Medical Center, Nashville, TN
*Purpose: A collaborative pharmacy practice agreement (CPPA) permits pharmacists to perform clinical services under the guidance of a supervising physician without direct physician intervention. We…
2020 American Transplant Congress
Medication Adherence in Thoracic Transplant Candidates
K. Pennington¹, R. Benzo¹, S. Jowsey¹, M. Budev², S. Chandreashekaran³, D. Erasmus⁴, E. Lease⁵, D. Levine⁶, K. Thompson¹, D. Yip⁴, B. Hardaway⁷, S. Dunlay¹, C. Kennedy¹
¹Mayo Clinic, Rochester, MN, ²Cleveland Clinic Foundation, Cleveland, OH, ³University of Florida, Gainesville, FL, ⁴Mayo Clinic, Jacksonville, FL, ⁵University of Washington, Seattle, WA, ⁶University of Texas Health Science Center, San Antonio, TX, ⁷Mayo Clinic, Scottsdale, AZ
*Purpose: Medication non-adherence is associated with poor outcomes in transplant recipients. It can be challenging to identify candidates at risk for medication non-adherence. The simplified…