Am J Transplant, Volume 20, Suppl 3 Archives - Page 84 of 223 - ATC Abstracts

2020 American Transplant Congress
The Protective Effect of Hypothermic Oxygenated Machine Perfusion (HOPE) Onresuscitating Steatotic Liver and its Underlying Mechanism
F. Lin¹, F. Zhen¹, X. Yan¹, L. Wenjin¹, Y. Qifa²
¹Zhongnan Hospital of Wuhan University, Wuhan, China, ²Zhongnan Hospital of Wuhan University/The Third Xiangya Hospital of Central South University, Wuhan/Changsha, China
*Purpose: To analyze the impact of steatotic livers with conventional cold storage (CS) and hypothermic oxygenated perfusion (HOPE) approaches, and further to investigate the rescue…
2020 American Transplant Congress
XIAP Enhances Xenoislet Survival: Novel Models to Evaluate Pretransplantation Gene Modifications
G. R. Devi¹, Z. Fitch¹, M. Song¹, M. Ribeiro¹, A. McGowan¹, X. Luo², B. H. Collins¹, A. D. Kirk¹
¹Department of Surgery, Duke Univesity School of Medicine, Durham, NC, ²Division of Nephrology, Duke Univesity School of Medicine, Durham, NC
*Purpose: Porcine islet xenotransplantation offers a reliable and near limitless supply of islets for the treatment of type 1 diabetes. Intraportal infusion of cells exposes…
2020 American Transplant Congress
T Cells from Highly Sensitized Kidney Transplant Patients Display Distinct TCR Repertoires
S. Negi¹, M. Li¹, A. Rutman², S. Paraskevas¹, C. Polychronakos¹, J. Tchervenkov¹
¹RIMUHC, Montreal, QC, Canada, ²McGill University, Montreal, QC, Canada
*Purpose: Sensitization to HLA antigens limits patient’s access to renal transplantation and causes higher risk of acute rejection and graft loss. T-cells, B-cells and donor-specific…
2020 American Transplant Congress
Exploring Psychosocial Factors and Disparity in Liver Transplant
K. Schmidt
Dept. of Psychiatry & Behavioral Sciences, Emory University, Atlanta, GA
*Purpose: Trends in liver transplant (LT) have shifted, and increasingly, individuals with alcohol liver disease (ALD) are receiving LT without 6-months of sobriety (Lee &…
2020 American Transplant Congress
Machine Learning Improves Kidney Discard Predictability
M. Barah¹, S. Mehrotra²
¹IEMS Department, Northwestern University, Evanston, IL, ²IEMS Department, MEAS, Northwestern University, Evanston, IL
*Purpose: Despite the shortage of kidneys supply, 18%-20% of deceased donor kidneys are discarded annually.*Methods: The cohort consisted of adult deceased donor kidneys donated between…
2020 American Transplant Congress
Individualized Impact of Donation after Cardiac Death on Kidney Transplant Outcomes
S. Bae, A. Massie, J. Garonzik Wang, D. Segev
Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Increasing the use of kidneys from donation after cardiac death (DCD) donors is a potential solution to mitigate the current organ shortage. However, DCD…
2020 American Transplant Congress
Muscle Strength and Physical Functioning in Pediatric Kidney Transplant Recipients
K. Sgambat, K. Amatya, A. Moudgil
Nephrology, Children's National, Washington, DC
*Purpose: Children with end stage renal disease on dialysis are known to be at high risk for protein energy wasting and low muscle mass, however…
2020 American Transplant Congress
Free Fatty Acids and Delayed Graft Function after Kidney Transplantation: A Single Center Analysis
J. Zhou¹, J. Lyu¹, X. Yu¹, C. Wu², J. Chen¹
¹The First Affiliated Hospital Kidney Disease Center, College of Medicine, Zhejiang University, Hangzhou, China, ²Global Health Research Center, Duke Kunshan University, Kunshan, China
*Purpose: Delayed graft function (DGF) is one of the most common obstacles of donation after circulatory death (DCD) kidney transplantation. Serum free fatty acids (FFAs)…
2020 American Transplant Congress
Cigarette Smoking and Long-Term Renal Function and Cardiovascular Disease in Living Kidney Donors
S. Getsin¹, M. Waldram¹, Y. Yu¹, D. Brennan¹, F. Al Ammary¹, J. Garonzik-Wang¹, M. Henderson¹, J. Locke², R. Reed², K. Lentine³, D. Segev¹, A. Massie¹
¹Johns Hopkins School of Medicine, Baltimore, MD, ²University of Alabama at Birmingham School of Medicine, Birmingham, AL, ³Saint Louis University School of Medicine, St. Louis, MO
*Purpose: Since cigarette smoking is a major risk factor for kidney and cardiovascular disease in the general population, many programs advise living kidney donor candidates…
2020 American Transplant Congress
Delayed Introduction of Mammalian Inhibitors of Rapamycin (mTOR) Post Kidney Transplantation Might Avoid the Chronic Nephrotoxicity of Calcineurin Inhibitors. Herein We Are Reporting an Eight-Years Single Center Experience of mTOR-Based Immunosuppression Regimen in Comparison with Cyclosporin-Based Regimen
W. A. Hassan¹, H. M. Tawfik²
¹Medicine-Nephrology, University of Tennessee Health Science Center, Memphis, TN, ²Medicine-Nephrology, Minia Nephrology Hospital, Minia University, Minia, Egypt
*Purpose: Delayed introduction of mTOR inhibitors post kidney transplantation might avoid the chronic nephrotoxicity of CNI: eight-years single center experience.*Methods: This is a retrospective analysis…