Am J Transplant, Volume 20, Suppl 3 Archives - Page 84 of 223 - ATC Abstracts

2020 American Transplant Congress
Liver Transplant Outcomes Across the Age Distribution and Interactions with County Health
S. K. Niazi¹, E. Vargas², A. Spaulding³, J. Crook², T. Schneekloth⁴, A. Keaveny⁵, A. Vasquez⁶, M. Gentry⁴, T. Rummans⁶, C. Taner⁵
¹Psychiatry & Psychology; Transplantation, Mayo Clinic, Jacksonville, FL, ²Health Sciences Research, Mayo Clinic, Jacksonville, FL, ³Heath Sciences Research, Mayo Clinic, Jacksonville, FL, ⁴Psychiatry & Psychology, Mayo Clinic, Rochester, MN, ⁵Transplantation, Mayo Clinic, Jacksonville, FL, ⁶Psychiatry & Psychology, Mayo Clinic, Jacksonville, FL
*Purpose: We examined risk of graft failure and patient mortality after liver transplant (LT) across the age continuum and county Health Outcomes & Health Factors…
2020 American Transplant Congress
Analyzing Causes for Death-Censored Graft Failure
M. Mayrdorfer, L. Liefeldt, N. Lachmann, W. Düttmann-Rehnolt, F. Halleck, M. G. Naik, P. Glander, K. Budde
Charité Universitätsmedizin Berlin, Berlin, Germany
*Purpose: Since it has been proposed that several causes could contribute to graft loss (GL), we analyzed graft failure in our center and attributed a…
2020 American Transplant Congress
Preclinical Study for Liver Allograft Tolerance after Rapid Immunosuppression Withdrawal Using Cynomolgus Monkeys
H. Sakai¹, E. Berglund¹, S. Chaudhry¹, Y. Kato¹, J. Weiner¹, P. Alonso-Guallart¹, N. Llore¹, K. Bruestle¹, F. Fredriksson¹, J. Stern¹, D. Ekanayake-Alper¹, M. Martinez², G. Pierre¹, M. Danton¹, S. Kofman¹, D. Ordanes¹, J. Lefkowitch³, A. Iuga¹, T. Kato⁴, M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Departments of Pathology and Cell Biology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Operational tolerance of liver allografts occurs in highly selected patients but cannot be reliably induced. Herein, we investigated if tolerance to liver can be…
2020 American Transplant Congress
Black Patients with Cirrhosis Have Worse Liver-Related Outcomes: A Large Multicenter Study
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, L. G. Gabra⁵, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Department of Surgery, Tulane Abdominal Transplant Institute, New Orleans, LA, ³Center for Health Information Partnerships, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL, ⁵Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: Racial disparity is influential in liver cirrhosis. Estimates of its magnitude have been limited by lack of large, longitudinal data that track patients from…
2020 American Transplant Congress
Long-Term Outcomes of Patients with Epstein-barr Virus-Driven Post-Transplant Lymphoproliferative Disease Following Solid Organ Transplant or Allogeneic Hematopoietic Cell Transplant Treated with Tabelecleucel in an Expanded Access Program Study
S. Prockop¹, R. Reshaf², D. Tsai³, N. Bunin⁴, R. Abu-Arja⁵, K. Mahadeo⁶, W. Weng⁷, K. Van Besien⁸, D. Loeb⁹, S. Dwivedy Nasta¹⁰, E. Nemecek¹¹, M. Hiremath¹², S. Yue¹², Y. Sun¹², W. Navarro¹², S. Nikiforow¹³
¹Memorial Sloan Kettering Cancer Center, New York, NY, ²Columbia University Irving Medical Center, New York, NY, ³Loxo Oncology, Stamford, CT, ⁴The Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶MD Anderson Cancer Center, Houston, TX, ⁷Stanford University School of Medicine, California, CA, ⁸Weill Cornell Medical College, New York, NY, ⁹Children's Hospital at Montefiore, Bronx, NY, ¹⁰University of Pennsylvania, Philadelphia, PA, ¹¹Oregon Health & Science University, Portland, OR, ¹²Atara Biotherapeutics, New York, NY, ¹³Dana Farber Cancer Institute, Boston, MA
*Purpose: There is a need for effective, well‑tolerated therapies in pts who develop Epstein-Barr virus-driven post-transplant lymphoproliferative disease (EBV+ PTLD) after solid organ (SOT) or…
2020 American Transplant Congress
Long-Term Outcomes with Islet Alone and Islet-after-Kidney Transplantation for Type 1 Diabetes in the Clinical Islet Transplantation Consortium
M. R. Rickels¹, T. L. Eggerman², L. Bayman³, J. C. Qidwai³, R. Alejandro⁴, N. D. Bridges⁵, B. J. Hering⁶, J. F. Markmann⁷, P. A. Senior⁸, L. G. Hunsicker³
¹Institute for Diabetes, Obesity & Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ²National Institute of Diabetes and Digestive and Kidney Disease, Bethesda, MD, ³University of Iowa, Iowa City, IA, ⁴University of Miami, Miami, FL, ⁵National Institute of Allergy and Infectious Disease, Bethesda, MD, ⁶University of Minnesota, Minneapolis, MN, ⁷Massachusetts General Hospital, Boston, MA, ⁸University of Alberta, Edmonton, AB, Canada
*Purpose: Phase 3 studies of islet transplant alone (ITA; n=48) and islet-after-kidney (IAK; n=24) transplantation in type 1 diabetes complicated by severe hypoglycemic events (SHE)…
2020 American Transplant Congress
Orthogonal IL-2 Cytokine-Receptor Pair Capable of Selective Expansion of Regulatory T Cells Facilitates Alloengraftment
T. Hirai¹, F. Simonetta², L. L. Su³, L. Picton³, J. Baker², J. Lin⁴, P. Li⁴, W. J. Leonard⁴, K. C. Garcia³, R. S. Negrin²
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Division of Blood and Marrow Transplantation, Stanford University, Stanford, CA, ³Departments of Molecular and Cellular Physiology and Structural Biology, Stanford University, Stanford, CA, ⁴Laboratory of Molecular Immunology, National Institutes of Health, Bethesda, MD
*Purpose: Adoptive transfer of regulatory T cells (Tregs) has been shown to improve alloengraftment in animal models. However, ex vivo Treg expansion for the purpose…
2020 American Transplant Congress
Frailty Prevalence among Younger and Older Kidney Transplant Candidates and Recipients
X. Chen¹, N. Chu¹, J. Walston², D. Segev¹, M. McAdams DeMarco¹
¹Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Frailty is associated with decreased access to kidney transplantation and poor post kidney transplant (KT) outcomes. This paper aims to explore the prevalence and…
2020 American Transplant Congress
Can Predonation Ambulatory Blood Pressure Monitoring Predict Postdonation Renal Function?
M. Mohamed Ahmed, M. Posadas Salas, D. Taber, V. Rao, K. Soliman, M. Casey
Medical University of South Carolina, Charleston, SC
*Purpose: Data on living kidney donor outcomes are of topical interest to the transplant community. Despite thorough pre-donation screening and risk assessment, a minority of…
2020 American Transplant Congress
Liver Transplantation of Hepatitis C Viremic Donors to Hepatitis C Naive Recipients
R. K. Gilroy, F. Lopez-Verdugo, G. Harmston, S. Fujita, M. E. Boschert, I. Zendejas, E. J. Frech, A. Gagnon, R. Jones, J. Krong, S. Sell, S. Dow, L. Lindberg, M. Rodriguez-Davalos, D. Alonso
Transplant Services, Intermountain Healthcare, Murray, UT
*Purpose: This study describes outcomes, out to 3 years, at one of the first centers in the United States to begin Hepatitis C Virus (HCV)-Nucleic…