ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Outcomes in Liver Transplantation with Use of Granulocyte-Colony Stimulating Factor

    K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: Questions remain if treatment with a granulocyte-colony stimulating factor (G-CSF) impacts clinical outcomes after liver transplant. The purpose of this study was to compare…
  • 2020 American Transplant Congress

    Unexpected Regulation of Foxp3+ Treg Production, Stability and Function by the Nuclear Co-Repressor, Sin3A

    L. M. Christensen1, T. Akimova2, R. Han1, L. Wang1, A. Samanta1, W. W. Hancock2

    1Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 2Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

    *Purpose: Foxp3+ T-regulatory (Treg) cells are crucial to immune homeostasis and self-tolerance, but the contributions to Tregs of the 4 large, multiprotein nuclear complexes (Sin3,…
  • 2020 American Transplant Congress

    Co-Stimulatory Blockade Immunosuppression Facilitates Lung Allograft Acceptance Through an Increase in Local IL-5 Production by Type 2 Innate Lymphoid Cells

    Y. Guo, Z. Mei, A. Hata, B. Mahgoub, D. Li, A. Manafi, A. Banerjee, A. Gelman, D. Kreisel, A. Krupnick

    Surgery, University of Virginia, Charlottesville, VA

    *Purpose: We have recently demonstrated that co-stimulatory blockade (CSB)-induced mouse lung allograft acceptance depends on a rapid influx of eosinophils that function to downregulate T…
  • 2020 American Transplant Congress

    Eplet Mismatch Not Correlated with Antibody Mediated Rejection or Allograft Loss Among Kidney Transplant Recipients with De Novo Donor Specific Antibody

    A. Basu1, W. Jiqiu2, A. Bentall2, M. Gandhi2, B. Dukek2, N. Henderson2, C. Schinstock2

    1Emory Healthcare, Atlanta, GA, 2Mayo Clinic, Rochester, MN

    *Purpose: Eplet mismatches are associated with development of de novo DSA (dnDSA) in kidney transplant recipients. However, it remains unclear how the degree of eplet…
  • 2020 American Transplant Congress

    Normothermic Machine Perfusion of Extended Criteria Donor Livers: Identification of Protein Biomarkers Predictive of Graft Viability and Post-Transplant Complications

    L. L. Wallace1, J. Attard1, Y. Boteon1, R. Laing1, J. Yu2, T. Perera3, D. Mirza3, H. Mergental3, S. Afford1

    1Centre for Liver and Gastrointestinal Research, University of Birmingham and the NIHR Biomedical Research Centre, UHB NHS Foundation Trust, Birmingham, United Kingdom, 2School of Biosciences, Advanced Mass Spectrometry Facility, University of Birmingham, Birmingham, United Kingdom, 3Liver Unit, The Queen Elizabeth Hospital, Birmingham, United Kingdom

    *Purpose: The Viability Testing and Transplantation of mArginal donor Livers Clinical Trial (VITTAL) demonstrated the capacity of Normothermic Machine Perfusion (NMP) to increase the proportion…
  • 2020 American Transplant Congress

    The Experience of 1000 Cases of Hand Assisted Laparoscopic Donor Nephrectomy for Living Donor Kidney Transplantation

    T. Hiramitsu1, T. Tomosugi1, K. Futamura1, M. Okada1, N. Goto1, S. Narumi1, K. Uchida2, Y. Watarai1

    1Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan, 2Masuko Memorial Hospital, Nagoya Aichi, Japan

    *Purpose: Due to the increasing number of kidney transplant candidates, living donor kidney transplantation becomes more necessary. For living donor kidney transplantation, safe and efficient…
  • 2020 American Transplant Congress

    Retinal Vein Occlusion Incidence in Kidney Transplant Recipients in South Korea: A Long-Term Population-Based Study

    J. Lee1, S. Park1, J. Kim1, M. Yu2, S. Baek3, K. Han4, D. Kim1, K. Joo1, Y. Kim1, H. Lee1, Y. Kim1

    1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea, Republic of, 3Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea, Republic of, 4Medical Statistics, College of Medicine, Catholic University of Korea, Seoul, Korea, Republic of

    *Purpose: The risk of retinal vein occlusion(RVO) is known to increase in patients with chronic kidney disease, especially end-stage renal disease (ESRD). However, little is…
  • 2020 American Transplant Congress

    Impact of Catch-Up Vaccinations on Anti-HLA Antibody Responses in Pediatric Kidney Transplant Candidates

    H. Sweiss1, J. Lyons2, R. Hall1, K. Hitchman3, D. Ranch4, E. Kincaide1, B. Crowther5

    1University Health System, San Antonio, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2Loyola University Medical Center, Chicago, IL, 3University Health System, San Antonio, TX, 4The University of Texas Health Science Center at San Antonio, San Antonio, TX, 5University of Colorado Health, Aurora, CO

    *Purpose: Evaluate antibody (Ab) response after catch-up vaccinations in pediatric kidney transplant candidates (PKTC).*Methods: A single center retrospective review of PKTC less than or equal…
  • 2020 American Transplant Congress

    Safety of Belatacept in HIV-Positive Kidney Transplant Recipients

    K. El Sakhawi1, A. Scemla2, D. Bertrand3, C. Garrouste4, P. Malvezzi5, P. Grimbert1, M. Matignon1

    1Nephrology, APHP Henri Mondor, Créteil, France, 2Nephrology, APHP Necker Enfants Malades, Paris, France, 3Nephrology, CHU Bois Guillaume, Rouen, France, 4Nephrology, CHU Clermond Ferrand, Clermont Ferrand, France, 5Nephrology, CHU Grenoble, Grenoble, France

    *Purpose: Kidney allograft survival in HIV-infected patients is lower than in the general population. Belatacept (instead of anticalcineurins (CNI)) has been shown to have a…
  • 2020 American Transplant Congress

    Liver Transplantation of Donors and Recipients’ with Situs Inversus Totalis: Case Reports and Literature Review

    L. Del Angel Diaz, A. Simioni, G. D'Amico, Q. Liu, K. Hashimoto, M. Fujiki, B. Eghtesad, F. Aucejo, K. Sasaki, C. Kwon, C. Miller, C. Quintini, T. Diago-Uso

    Cleveland Clinic, Cleveland, OH

    *Purpose: Situs Inversus Totalis (SIT) is a rare condition affecting 0.1% of the general population. It was historically a contraindication for LTx and graft donation.…
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