ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Improved Outcomes Over the Past 13 Years in HIV Positive Kidney Transplant Recipients-A Single Center Experience

    A. Mattiazzi1, J. F. Camargo2, S. Anjan2, M. I. Morris2, L. Abbo2, J. Simkins2, Y. Natori2, K. Aoke3, A. Zilli3, R. Thurston3, M. Muldoon3, L. Preczewski3, L. J. Chen4, G. W. Burke4, G. Ciancio4, G. Guerra1

    1Medicine. Division of Nephrology, University of Miami/Miami Transplant Institute, Miami, FL, 2Medine. Division of Infectious Disease, University of Miami/Miami Transplant Institute, Miami, FL, 3Miami Transplant Institute, Miami, FL, 4Surgery, University of Miami/Miami Transplant Institute, Miami, FL

    *Purpose: Kidney transplantation in HIV positive recipients (HIV+) is the treatment of choice for renal failure in patients (P) who maintain CD4+ counts ≥ 200/mm3and…
  • 2020 American Transplant Congress

    The Impact of the New Heart Allocation Policy on the Treatment of United States Adult Heart Transplant Candidates

    K. Chung1, A. S. Anderson2, M. Siegler1, M. M. Churpek3, W. Parker1

    1University of Chicago Pritzker School of Medicine, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3University of Wisconsin School of Medicine and Public Health, Madison, WI

    *Purpose: In October 2018, the US heart allocation system expanded the number of priority “Status” tiers from 3 to 6 and added cardiogenic shock requirements.…
  • 2020 American Transplant Congress

    Automated Monitoring of Four Urinary Biomarkers in Routine Surveillance Identifies Patients at Low and High Risk of Renal Allograft Injury

    L. Sheward1, J. Wedel1, N. Rodig1, R. Mannon2, O. Bestard3, V. Dharnidharka4, D. Zurakowski1, A. Kho1, T. Blydt-Hansen5, M. Seifert2, D. M. Briscoe1

    1Boston Children's Hospital, Boston, MA, 2University of Alabama at Birmingham, Birmingham, AL, 3Bellvitge University Hospital, Barcelona, Spain, 4St Louis Children's Hospital, St Louis, MO, 5BC Children's Hospital, Vancouver, BC, Canada

    *Purpose: Surveillance renal biopsy data indicate that up to 36% of clinically stable kidney allograft recipients have subclinical rejection, emphasizing the need to implement automated…
  • 2020 American Transplant Congress

    PD-L1 Signals Lymphatic Endothelium for Treg Migration

    W. Piao1, L. Li1, K. Hippen2, Y. Zhang2, V. Saxena3, Y. Xiong1, C. Paluskievicz1, M. WillsonShirkey1, B. Blazar2, L. Riella4, J. Bromberg5

    1Surgery, U of Maryland, Baltimore, MD, 2Pediatrics, U of Minnesota, Minneapolis, MN, 3U of Maryland, Baltimore, MD, 4Transplantation Research Center, Harvard U, Boston, MA, 5Surgery and Microbiology and Immunology, U of Maryland, Baltimore, MD

    *Purpose: Regulatory T cell (Treg) migration is important for tolerance, although the molecules that regulate Treg entry to lymphatics are poorly understood. Lymphatic endothelial cells…
  • 2020 American Transplant Congress

    ATHENA – Patient and Allograft Outcome Differences after Kidney Transplantation – Germany vs. France

    F. Thaiss1, C. Sommerer1, B. Suwelack1, D. Dragun1, I. A. Hauser1, O. Witzke1, C. Hugo1, P. Schenker1, N. Kamar2, P. Merville2, I. Kroeger3, M. Junge3, B. Nashan1

    1Athena, Study Group, Germany, 2Athena, Study Group, France, 3Novartis Pharma GmbH, Nürnberg, Germany

    *Purpose: In the ATHENA trial [NCT01843348], efficacy and safety of everolimus in combination with tacrolimus [EVR+TAC] or cyclosporine A [EVR+CyA] vs. TAC and mycophenolic acid…
  • 2020 American Transplant Congress

    The Influence of the Donor Kidney Weight to Recipient Body Weight Ratio on Long-Term Renal Graft Outcomes

    S. Yang1, J. Lee1, Y. Jung2, B. Kim3, M. Kim1, S. Kim1, Y. Kim1, K. Huh1

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Nephrology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: To study the impact of the relative donor kidney size on long-term graft function and survival, we investigated the living donor renal transplants outcomes.*Methods:…
  • 2020 American Transplant Congress

    Health-Related Quality of Life after Anonymous Nondirected Living Liver Donation: A Multi-Center, North American Collaboration

    M. H. Raza1, W. E. Jackson2, A. Dell3, L. Ding4, J. Shapiro3, E. A. Pomfret5, Y. Genyk6, L. Sher6, J. Emamaullee6

    1Keck School of Medicine of USC, Los Angeles, CA, 2Gastroenterology, University of Colorado, Aurora, CO, 3Surgery, University of Alberta, Edmonton, AB, Canada, 4Preventive Medicine, University of Southern California, Los Angeles, CA, 5Surgery, University of Colorado, Aurora, CO, 6Surgery, University of Southern California, Los Angeles, CA

    *Purpose: Literature on anonymous or ‘altruistic’ nondirected living liver donors (ND-LLDs) remains sparse as living donor liver transplant (LDLT) programs continue to explore the utilization…
  • 2020 American Transplant Congress

    Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation

    J. L. Saullo, A. Ferrari, E. M. Eichenberger, J. M. Steinbrink, A. W. Baker, M. Bacchus, E. K. Maziarz, S. Kakoullis, L. Zaffiri, H. Berry, J. M. Reynolds, C. R. Wolfe

    Duke University Medical Center, Durham, NC

    *Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…
  • 2020 American Transplant Congress

    Proposed New Pancreas Allocation Policy: Moving to Concentric Circles as First Unit of Allocation

    A. Israni1, S. Gustafson1, B. Thompson1, A. Wey1, S. Niederhaus2, R. Forbes3, A. Fox4, B. Kasiske1, J. Snyder1

    1SRTR, Minneapolis, MN, 2Univ of Maryland, Baltimore, MD, 3Vanderbilt Univ, Nashville, TN, 4UNOS, Richmond, VA

    *Purpose: The Organ Procurement and Transplantation Network (OPTN) proposed a new national deceased donor pancreas allocation policy that removes donor service area and OPTN region…
  • 2020 American Transplant Congress

    Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation

    H. Hirao1, T. Ito1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, R. W. Busuttil1, F. M. Kaldas1, J. W. Kupiec‐Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
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