ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Enhancing Kidney Allograft Decision Making: An Organ Offer Simulation Study

    J. Mansy1, J. Case1, D. Stewart2, H. McGehee2, K. Lindblad2, R. Schaffer1, J. Fisher1, J. Rice1, S. Kurian1, C. Marsh1

    1Scripps Center for Organ and Cell Transplantation, La Jolla, CA, 2United Network for Organ Sharing Research Department, Richmond, VA

    *Purpose: This study was designed to identify opportunities to improve UNOS organ allocation as well as providers’ decision-making process for cadaveric kidney offers. Using its…
  • 2020 American Transplant Congress

    Serum αKlotho after Living Kidney Donation: A Systematic Review and Meta-Analysis

    W. Cheungpasitporn1, C. Thongprayoon2, N. Leeaphorn3, M. A. Mao4, J. A. Neyra5

    1Nephrology, University of Mississippi Medical Center, Jackson, MS, 2Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 3Renal Transplant Program, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO, 4Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL, 5Nephrology, University of Kentucky, Lexington, KY

    *Purpose: αKlotho (klotho) is a known anti-aging protein that exerts diverse physiological effects. Defect in klotho gene expression in mice can result in a syndrome…
  • 2020 American Transplant Congress

    Reverse Epidemiology and the Obesity Paradox for Patients with Chronic Kidney Disease

    R. A. Choudhury1, D. Yoeli1, H. B. Moore1, H. Yaffe1, G. Hoeltzel2, K. R. Dumon3, N. N. Williams3, P. L. Abt4, K. D. Conzen1, T. L. Nydam1

    1Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2Thomas Jefferson University Hospital, Philadelphia, PA, 3University of Pennsylvania Hospital, Philadelphia, PA, 4Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA

    *Purpose: Obesity has been associated with both increased progression of chronic kidney disease as well as with a paradoxical improvement in survival among ESRD patients…
  • 2020 American Transplant Congress

    Clazakizumab (Anti-IL-6 Monoclonal) as an Agent to Reduce Donor Specific Hla Antibodies (DSA) and Improve Outcomes in Patients with Chronic & Active Antibody-Mediated Rejection Post-Kidney Transplantation (NCT03380377)

    S. C. Jordan, N. Ammerman, M. Toyoda, S. Ge, E. Huang, A. Peng, S. Sethi, R. Najjar, E. Ortiz, M. Chu, A. De Guzman, I. Kim, K. Lim, J. Choi, A. Vo

    Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: Highly sensitized (HS) patients are at an increased risk for chronic antibody mediated rejection (cABMR) and graft loss due to persistent, deleterious DSA production.…
  • 2020 American Transplant Congress

    Multi- National Survey among Nephrologists & Transplant Surgeons About the Suitability and Acceptance of the Marginal Live Kidney Donors with Sickle Cell Trait

    Z. Arabi1, A. Mateen1, A. Altheaby1, M. Bukhari2, A. Hamad3, S. Kaysi4, E. Elhassan1

    1KAMC, Riyadh, Saudi Arabia, 2Taif University, Taif, Saudi Arabia, 3The Regional Medical Center, Orangeburg, SC, 4CHU Clermont-Ferrand, Saint Pryv/ Saint Mesmin, France

    *Purpose: Due to organ shortage, many transplant centers may consider “marginal” kidney donors as those with sickle cell trait ( SCT) for donation. Acceptance of…
  • 2020 American Transplant Congress

    A Large Single Center Analysis of Medical and Surgical Complications Associated with Obesity after Kidney Transplantation in the Current Era

    F. Aziz, A. Ramadorai, S. Parajuli, N. Garg, M. Mohamed, D. Mandelbrot, D. Foley, M. Garren, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: Medical and surgical complications associated with obesity after kidney transplantation in the current era are unknown.*Methods: We analyzed the records of consecutive first-time, kidney…
  • 2020 American Transplant Congress

    Outcomes of De Novo Belatacept-Based Immunosuppression in Recipients of Kidneys at High Risk for Delayed Graft Function in the Setting of Lymphocyte Depleting Immune Modulation

    T. L. Shertel1, M. A. Wynd1, M. A. Pereiras1, J. T. McKeen1, Y. Y. Yushkov2, B. R. Schleich3, S. E. Geatrakas2, A. Patel2, M. J. Goldstein2

    1Pharmacy, Hackensack University Medical Center, Hackensack, NJ, 2Organ Transplant, Hackensack University Medical Center, Hackensack, NJ, 3Patient Safety and Quality, Hackensack University Medical Center, Hackensack, NJ

    *Purpose: Our center created an immunosuppression protocol using de novo belatacept (DNB) in the setting of lymphocyte depletion to increase the utilization of deceased donor…
  • 2020 American Transplant Congress

    Treprostinil is Safe and Potentially Useful in Preventing Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplant Recipients

    R. Venkataramanan1, I. H. Shaik2, V. C. Pillai3, O. A. Almazroo4, M. K. Miah5, R. Xu2, S. Dharmayan2, A. Al-Khafaji2, S. Ganesh2, M. Molinari2, A. Tevar2, C. Hughes2, A. Humar2

    1School Of Pharmacy, University of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3US Food and Drug Administration,, Silver Spring, MD, 4Saudi FDA, Riyadh, Saudi Arabia, 5Astra Zeneca, Boston, MA

    *Purpose: Ischemia and reperfusion injury (IRI) is one of the unavoidable complications in orthotopic liver transplantion. Hepatic ischemic injury begins during the preservation of the…
  • 2020 American Transplant Congress

    Is the Survival Impacted by Multiple Cancer after Liver Transplantation? A Retrospective French National Multicentric Study between 1993-2013

    M. Altieri

    Chu Caen, Caen, France

    *Purpose: Introduction: Despite the great progress made in recent decades, post-liver transplant de novo cancers is one of the leading causes of late complications and…
  • 2020 American Transplant Congress

    Comparing Post-Transplant Outcomes in Living and Deceased Donor Liver Transplantation for Patients with Hepatocellular Carcinoma: An Analysis of UNOS Registry

    T. Kitajima1, D. Moonka2, S. Yeddula1, M. Rizzari1, K. Collins1, A. Yoshida1, M. S. Abouljoud1, S. Nagai1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI

    *Purpose: Because of possible short waiting time, living donor liver transplantation (LDLT) for HCC may provide survival benefit compared to deceased donor LT (DDLT). This…
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