ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Inflammatory Response in the Context of Tissue Injury: Roles of Tyro3, Axl, and Mer (TAM) Receptors in Liver Ischemia/Reperfusion Injury

    J. Zhang, M. Ni, D. Jin, H. Zhang, R. Busuttil, J. Kupiec-Weglinski, Y. Zhai

    Dumont-UCLA Transplant Center, Los Angeles, CA

    *Purpose: Although the inflammatory response in liver ischemia reperfusion injury has been studied extensively, how the context of tissue injury (presence of necrotic/apoptotic cells) regulates…
  • 2020 American Transplant Congress

    Daratumumab for Desensitization and Antibody Mediated Rejection Treatment in Highly-HLA Sensitized Patients

    S. Jordan, R. Vescio, N. Ammerman, M. Toyoda, S. Ge, M. Chu, J. Hou, E. Huang, A. Peng, S. Sethi, R. Najjar, K. Lim, J. Kobashigawa, J. Patel, E. Kransdorf, A. Vo

    Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: Highly-HLA sensitized (HS) patients have an immunologic barrier to transplantation. ABMR promotes graft loss and poor patient survival. Methods to reduce anti-HLA antibodies are…
  • 2020 American Transplant Congress

    Mass-Spectrometry Based Discovery of Tubular Injury Marker in Chronic Kidney Disease

    J. Kim1, D. Han1, J. Jeong2, J. Moon1, S. Lee3, Y. Kim1, K. Yoo4, D. Kim1, Y. Kim1, S. Yang1

    1Seoul National University Hospital, Seoul, Korea, Republic of, 2Veterans Health Service Medical Center, Seoul, Korea, Republic of, 3Kangwon National University Hospital, Kangwon-do, Korea, Republic of, 4Ulsan National University Hospital, Ulsan, Korea, Republic of

    *Purpose: Renal tubular injury and interstitial fibrosis are inevitable processes in the progression of chronic kidney disease (CKD). The purpose of this study is to…
  • 2020 American Transplant Congress

    Temporal Trends in Depression and Anxiety in Potential Live Kidney Donors

    A. Ravi, D. Bakhai, E. Clifton, S. Norman, A. Naik, Y. Lu, R. Parasuraman, M. Doshi

    University of Michigan, Ann Arbor, MI

    *Purpose: Psychosocial factors, including mental health status, are an important part of donor evaluation due to its altruistic nature. Yet, little is known about the…
  • 2020 American Transplant Congress

    Evaluation of Clinical Outcomes in Patients Receiving Antithrombotic Therapy Prior to Kidney Transplantation

    A. Diamond1, C. Antonacci2, K. Lau3, A. Di Carlo3, S. Karhadkar3

    1Pharmacy, Temple University Hospital, Philadelphia, PA, 2Temple University School of Medicine, Philadelphia, PA, 3Surgery, Temple University Hospital, Philadelphia, PA

    *Purpose: Patients with end stage renal disease (ESRD) often have significant cardiovascular comorbidities. Utilization of therapeutic anticoagulation (AC) and/or antiplatelet (AP) therapy poses an increased…
  • 2020 American Transplant Congress

    Transition from Youth to Adult Care of Kidney Transplant Recipients: Single Center Experience

    L. Ganesan, A. McGrath, K. Dahl, K. Dinello, A. Fong, L. Maestretti, M. Patton, P. Grimm, A. Chaudhuri

    Pediatric Nephrology, Lucile Packard Children's Hospital, Stanford, CA

    *Purpose: Transition of transplant recipients from youth to adult care has been a challenge for many. Starting in March 2017, Lucile Packard Children’s Hospital (LPCH)…
  • 2020 American Transplant Congress

    Comparison of 4 vs 14 Days Early Steroid Withdrawal in Kidney Transplant Recipients

    O. Adebiyi, J. Chen, B. Brady, S. Mietz, T. Taber, D. Mishler, M. Yaqub, W. Goggins, A. Sharfuddin

    Indiana University, Indianapolis, IN

    *Purpose: The optimal duration, as well as the dose of the initial steroid use, is not known as it varies widely among institutions that have…
  • 2020 American Transplant Congress

    MTOR Inhibitor Management and Wound Complications in Liver Transplant Recipients Undergoing Subsequent Surgeries

    K. Neuhaus, B. Eghtesad, K. Hashimoto, M. Spinner, J. Bollinger, J. Eckardt

    Cleveland Clinic, Cleveland, OH

    *Purpose: Class-related, concentration-dependent adverse effects associated with mTOR inhibitors (mTORi) include wound complications such as impaired wound healing, incisional hernias, hepatic artery thrombosis, and lymphocele…
  • 2020 American Transplant Congress

    Reducing Travel While Improving Geographic Equity: Continuous Distribution with “Gravity Functions”

    M. Mankowski1, N. Wood2, S. Gentry2, D. Segev3

    1King Abdullah University of Science and Technology, Thuwal, Saudi Arabia, 2US Naval Academy, Annapolis, MD, 3Johns Hopkins University, Baltimore, MD

    *Purpose: Recently, the OPTN board selected the continuous distribution framework for future organ allocation changes. Continuous distribution allocates organs without geographic boundaries, for example, by…
  • 2020 American Transplant Congress

    Long Term Ursodeoxycholic Acid Use Does Not Alter Long Term Rejection, Biliary Complication, Mortality or Hospitalization Rates after Liver Transplantation

    T. Ashraf1, V. Mendiratta2, S. Gill1, A. Abdelwahab3, D. Moonka2, S. Jafri2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 3Wayne State University, Detroit, MI

    *Purpose: Endogenous bile acids are suspected to contribute to hepatobiliary injury after liver transplantation through direct cytotoxic effects. Ursodeoxycholic acid (UDCA) has been shown to…
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