Am J Transplant, Volume 20, Suppl 3 Archives - Page 76 of 223 - ATC Abstracts

2020 American Transplant Congress
Evaluation of a Surveillance after Prophylaxis Strategy for Cytomegalovirus Prevention in Liver Transplant Recipients
N. Parrish¹, A. Webb², T. Kaiser¹, S. Shah¹, N. Anwar¹, K. Luckett¹
¹University of Cincinnati Med Ctr, Cincinnati, OH, ²Tampa General Hospital, Tampa, FL
*Purpose: Despite prophylaxis and preemptive strategies, CMV infection remains a common complication post liver transplant (LT). CMV surveillance after prophylaxis may improve outcomes, but supporting…
2020 American Transplant Congress
The Value of Pharmacist-Driven Valganciclovir Dosing in Kidney Transplant Recipients in Reducing CMV Infection: A Single Center Experience
K. D. Belfield¹, C. E. Costello², M. Malinis³
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, ²University of Connecticut School of Pharmacy, Storrs, CT, ³Section of Infectious Diseases,, Yale School of Medicine, New Haven, CT
*Purpose: Cytomegalovirus (CMV) is a common viral infection after kidney transplant (KT) despite prophylaxis with valganciclovir (VGCV). VGCV is renally dosed and can be a…
2020 American Transplant Congress
Pathological Characteristics of BK Polyomavirus Nephropathy with Glomerular Involvement
G. Huang¹, X. Chen¹, W. Chen², S. Yang², J. Qiu¹
¹Department of Organ Transplantation, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China, ²Department of Pathology, 1st Affiliated Hospital, Zhongshan University, Guangzhou, China
*Purpose: This study aimed to investigate the pathological characteristics of BK polyomavirus-associated nephropathy with glomerular involvement in kidney transplant recipients.*Methods: Forty-four patients with glomerular BK…
2020 American Transplant Congress
Improving Consent Rate for High Kidney Donor Profile Index Kidneys
L. Malinzak, A. Patel, A. Malilay, K. Dandron, A. Landrum, S. Gray, L. Lewis, K. Lord, R. Stampley, D. Kim
Henry Ford Hospital, Detroit, MI
*Purpose: Many deceased donor kidneys remain unused in this country. The UNOS formed Collaborative Improvement and Innovation Networks (COIIN) to tackle this issue, in which…
2020 American Transplant Congress
Infections in Simultaneous Pancreas/Kidney Transplant (SPKT) Recipients
J. W. O'Neill¹, M. J. Copeland², S. D. Schrank², M. Cooper³, P. Abrams³, B. Javaid³, J. G. Timpone²
¹Georgetown University School of Medicine, Washington, DC, ²Division of Infectious Diseases and Travel Medicine, Medstar Georgetown University Hospital, Washington, DC, ³Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC
*Purpose: Simultaneous pancreas/kidney transplant (SPKT) is indicated for diabetic patients (pts) with chronic kidney disease and represents the largest proportion of pancreas transplants performed. Infection…
2020 American Transplant Congress
Consistent Prevention of Perioperative Cardiac Xenograft Dysfunction with Non-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model
C. E. Goerlich¹, A. Singh¹, D. Kaczorowski¹, M. Abdullah¹, B. Lewis¹, I. Tatarov¹, A. Hershfeld¹, T. Zhang¹, P. Odonkor¹, A. Tabatabai¹, A. Bhutta¹, E. Strauss¹, B. Williams¹, D. Ayares², M. Mohiuddin¹
¹Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Revivicor, Blacksburg, VA
*Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
2020 American Transplant Congress
Is the Epitope Mismatch Load Enough to Identify HLA-DQ Mismatches with a Low Risk for De Novo DSA Development?
V. Jucaud¹, M. Stegall², C. Schinstock², R. Heilman³, L. Rebellato⁴, M. Samaniego-Picota⁵, D. Leeser⁴, M. Gandhi², J. Beaumont¹, M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²Mayo Clinic, Rochester, MN, ³Mayo Clinic, Phoenix, AZ, ⁴East Carolina University, Greenville, NC, ⁵Henry Ford Transplant Institute, Detroit, MI
*Purpose: The development of de novo donor-specific anti-HLA antibodies (dnDSA) remains a major risk factor for poor long-term kidney allograft outcomes. In particular, anti-HLA-DQ dnDSAs,…
2020 American Transplant Congress
Textbook Outcome: Definition and Analysis of a Novel Quality Measure in Kidney Transplantation
S. E. Halpern¹, D. Moris², B. I. Shaw², L. M. McElroy², M. J. Ellis³, D. Sudan², S. J. Knechtle², B. H. Collins², A. S. Barbas²
¹Duke University School of Medicine, Durham, NC, ²Department of Surgery, Duke University Medical Center, Durham, NC, ³Department of Medicine, Duke University Medical Center, Durham, NC
*Purpose: Textbook outcomes (TO) is an emerging concept in surgery, which represents an effort to define a standardized, composite quality metric based on multiple postoperative…
2020 American Transplant Congress
Torque Teno Virus Level for Risk Stratification of Subclinical Graft Rejection at 12 Months after Kidney Transplantation – An Prospective Observational Cohort Study
K. Doberer, E. Puchhammer, G. Böhmig, G. Bond
Medical University Vienna, Vienna, Austria
*Purpose: Non-invasive monitoring strategies are insufficient to detect patients at risk for subclinical graft rejection after kidney transplantation. The highly prevalent and non-pathogenic Torque Teno…
2020 American Transplant Congress
Integrated Multicohort Analysis of Transcriptome Profiles Identifies Blood Gene Signature to Distinguish Rejection from Infection in Patients with Solid Organ Transplants
L. C. Murphy, A. Rao, M. Donato, P. Khatri
School of Medicine, Stanford University, Stanford, CA
*Purpose: Allograft rejection and infection are now leading causes of morbidity and mortality in transplant recipients. Current diagnosis relies on nonspecific markers of graft injury,…