Am J Transplant, Volume 20, Suppl 3 Archives - Page 76 of 223 - ATC Abstracts

2020 American Transplant Congress
Effectiveness of Preemptive Therapy in the Prevention of Cytomegalovirus (CMV) Disease in High-Risk (Donor Seropositive/Recipient Seronegative) Liver Transplant Recipients
J. A. Morillas, K. Brizendine
Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Guidelines recommend preemptive therapy (PET) as one strategy for prevention of CMV disease in high risk liver transplant recipients (LTR). However, questions have been…
2020 American Transplant Congress
Methenamine for Prevention of Recurrent Urinary Tract Infections in Adult Solid Organ Transplant Recipients
H. Sweiss¹, S. Bhayana², R. Hall¹, J. Nelson¹, E. Kincaide¹
¹University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, ²University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: Evaluate efficacy of methenamine for prevention of recurrent urinary tract infections (rUTI) in transplant recipients.*Methods: This retrospective review included patients greater than or equal…
2020 American Transplant Congress
BK-Viral Nephropathy after Transplantation of a Non-Renal Organ
A. Schwarz¹, C. Bara², J. Braesen³, J. Gottlieb⁴
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Cardiothoracic Surgery Department, Hannover Medical School, Hannover, Germany, ³Pathology Department, Hannover Medical School, Hannover, Germany, ⁴Pulmonary Department, Hannover Medical School, Hannover, Germany
*Purpose: Patients with non-renal organ transplantation may suffer BK-viral nephropathy (BKVN) of their orthotopic kidneys by reactivation of their own viral population living in latency…
2020 American Transplant Congress
Mobile Application for Communication Increases the Efficiency of Organ Procurement and Transplantation
E. Pahl
Health Informatics, University of Iowa, Iowa City, IA
*Purpose: Donor organ recovery is a complex process involving organ procurement organizations and multiple surgical teams from various transplant centers. According to the Organ Preservation…
2020 American Transplant Congress
Early Pancreas Allograft Failure is Associated with Donor Hypertension
C. Masset¹, J. Branchereau¹, L. Badet², C. Kerleau¹, C. Legendre³, D. Glotz⁴, G. Karam¹, D. Cantarovich¹
¹University Hospital of Nantes, Nantes, France, ²University Hospital of Lyon, Lyon, France, ³Necker Hospital, Paris, France, ⁴Saint Louis Hospital, Paris, France
*Purpose: About 10% of pancreas allografts are lost prematurely due to thrombosis. Despite identification of numerous risk factors, the incidence of early failure did not…
2020 American Transplant Congress
Normothermic Machine Perfusion of Genetically Modified Pig Livers with Human Blood
D. Detelich¹, T. M. Coe², C. G. Rickert², C. Carroll², N. Serifis², R. Matheson², I. Rosales², W. Qin³, Y. Kan³, J. Layer³, M. Youd³, W. Westlin³, S. Kimura², A. Azimzadeh², L. Yang³, J. F. Markmann²
¹Tufts Medical Center, Boston, MA, ²Massachusetts General Hospital, Boston, MA, ³eGenesis, Cambridge, MA
*Purpose: Barriers to pig-to-human liver xenotransplantation remain, including profound thrombocytopenia, coagulopathy, and rejection. We utilized ex-vivo liver xenoperfusion with human blood to study the human…
2020 American Transplant Congress
HLA Mismatch Immunogenicity: Are We Predicating Mismatches That Induce De Novo DSA Development or That Do Not?
V. Jucaud¹, L. Rebellato², K. Briley², C. Haisch², S. Kendrick³, H. Jones³, K. Mclawhorn³, D. Leeser², M. Everly¹
¹Terasaki Research Institute, Los Angeles, CA, ²East Carolina University, Greenville, NC, ³Eastern Nephrology Associates, Greenville, NC
*Purpose: Although the development of de novo donor-specific anti-HLA antibodies (dnDSA) remains a major risk factor for poor long-term kidney allograft outcomes, the prediction of…
2020 American Transplant Congress
Chronic Diarrhea in Renal Transplant Recipients: A Metagenomic Study of Gut Microbiota Composition and Functionality
J. C. Swarte¹, R. M. Douwes¹, S. Hu², R. Gacesa², H. J. Harmsen³, R. K. Weersma², S. J. Bakker¹
¹Internal Medicine - Nephrology, University Medical Centre Groningen, Groningen, Netherlands, ²Gastroenterology and Hepatology, University Medical Centre Groningen, Groningen, Netherlands, ³Medical Microbiology, University Medical Centre Groningen, Groningen, Netherlands
*Purpose: Chronic diarrhea is a common problem in renal transplant recipients (RTR) and can lead to a lower quality of life. However, in many patients…
2020 American Transplant Congress
Relapse-Prone Unresectable Hepatoblastoma (HB) Requiring Liver Transplantation (LT) Are Immunogenic and May Be Sensitive to Immune Checkpoint Inhibitors
M. Ningappa¹, C. Ashokkumar¹, J. Garifallou², M. Gonzalez², H. Hakonarson², S. Ranganathan¹, B. W. Higgs¹, R. Sindhi¹
¹Pediatric Transplant, Pittsburgh, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: Unresectable HB accounts for 8% of all pediatric LT. Post-LT relapse rates approach 20% indicating a need for more effective neoadjuvant chemotherapy.*Methods: To discover…
2020 American Transplant Congress
Metformin Improves Biomarkers of Calcineurin Inhibitor Related Nephrotoxicity
M. R. Fernando, K. Taylor, S. Herath, A. Au, J. Erlich, Z. Endre
Department of Nephrology, Prince of Wales Hospital, Randwick, Australia
*Purpose: Calcineurin Inhibitors (CNIs) prevent transplant rejection but cause significant nephrotoxicity. Biomarkers of CNI nephrotoxicity could help drug dosing and improve long-term graft outcomes. As…