Am J Transplant, Volume 20, Suppl 3 Archives - Page 73 of 223 - ATC Abstracts

2020 American Transplant Congress
Glomerular Filtration Rate Based on Cystatin C Provides the Best Prediction of Cardiovascular Events and Mortality Compared to Measured GFR and Creatinine Based GFR in Kidney Transplant Recipients
L. Galapia¹, J. Lieske², A. Rule², H. Amer², N. Zhang¹, D. Butterfield¹, M. Keddis¹
¹Mayo Clinic, Scottsdale, AZ, ²Mayo Clinic, Rochester, MN
*Purpose: GFR estimated by cystatin C (CysC) is a better predictor of cardiovascular (CV) events and mortality compared to eGFR by creatinine (Cr) in native…
2020 American Transplant Congress
Predonation Hypertension and Early Postdonation Systolic Blood Pressure among Older Living Kidney Donors
F. Al Ammary¹, A. D. Muzaale², D. C. Brennan¹, D. L. Segev², A. B. Massie²
¹Medicine, Johns Hopkins University, Baltimore, MD, ²Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: One mechanism underlying predonation hypertension in older (age≥50) living kidney donors is a reduced number of nephrons. The 50% nephron mass reduction associated with…
2020 American Transplant Congress
Safety and Immunogenicity of Adjuvanted Recombinant Subunit Herpes Zoster Vaccine in Lung Transplant Recipients
C. Hirzel¹, V. H. Ferreira¹, A. G. L’Huillier¹, T. Ku¹, M. Ierullo¹, C. Miao², D. S. Schmid², J. Tikkanen¹, L. G. Singer¹, A. Humar¹, D. Kumar¹
¹University Health Network, Toronto, ON, Canada, ²CDC, Atlanta, GA
*Purpose: The new adjuvanted subunit recombinant herpes zoster vaccine (RZV; Shingrix™) may have potential utility in transplant patients for the prevention of shingles, but there…
2020 American Transplant Congress
Did the 250 Nautical Mile Circle Work? Geographic Disparities in Lung Transplantation Before and after the Policy Change
M. Kosztowski¹, Y. Yu², A. Massie², D. L. Segev², S. E. Gentry²
¹University of Iowa, Iowa City, IA, ²Johns Hopkins, Baltimore, MD
*Purpose: In November 2017, the lung allocation policy was challenged in court due to concern that candidates living in New York City were being disadvantaged…
2020 American Transplant Congress
Intravenous Administration of Mitochondria Minimizes Liver Ischemia Reperfusion Injury in Lean and Diet Induced Obese Mice
T. Rousselle¹, E. Patterson¹, C. Kuscu¹, J. Pierre², C. Kuscu¹, J. Eason¹, D. Maluf¹, V. Mas¹, A. Bajwa¹
¹Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ²Dept of Pediatrics, UTHSC, Memphis, TN
*Purpose: Ischemia induces altered bioenergetics within cells with increased mitochondrial swelling and reactive oxygen species and that ultimately degrade of cellular function. Ischemia reperfusion injury…
2020 American Transplant Congress
Long-term Functional Survival of Human Stem Cell-Derived Islets Microencapsulated in Alginate with CXCL12 in Non-Human Primates without Immunosuppression
M. C. Poznansky¹, D. Alagpulinsa¹, J. Lei², R. Pop³, D. Sobell⁴, M. Chapin¹, S. Collins³, A. Veres³, H. Deng², D. Melton³, J. Markmann²
¹Vaccine and Immunotherapy Center, Massachusetts General Hospital, Charlestown Navy Yard, MA, ²Transplant Surgery, Massachusetts General Hospital, Boston, MA, ³Harvard Stem Cell Institute, Harvard University, Cambridge, MA, ⁴Vaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA
*Purpose: Human pluripotent stem cell-derived islet-like cells (SC-islets) represent a practical source for beta-cell replacement to achieve a functional cure for type 1 diabetes. Long-term…
2020 American Transplant Congress
Improving Eligibility of Renal Transplants in the Elderly
L. B. Moraitis¹, J. Rogers², A. Farney¹, A. Reeves-Daniel¹, G. Orlando¹, W. Doares¹, S. Kaczmorski¹, A. Mena-Gutierrez¹, C. Jay¹, R. Stratta¹
¹Abdominal Organ Transplant, Wake Forest Baptist Health, Winston-Salem, NC, ²Surgery, Wake Forest Baptist Health, Winston-Salem, NC
*Purpose: In the recent past, older age was a contraindication to kidney transplantation (KT). New kidney allocation schemes with use of longevity matching, initiation of…
2020 American Transplant Congress
Low Diagnostic Yield of Protocol Allograft Biopsy Performed During DGF in Deceased Donor Kidney Transplant Recipients Treated with Induction and Standard-Dose CNI-Based Maintenance
E. Favi¹, A. James², M. Ferraresso¹, R. Cacciola³
¹Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, ²Renal Transplantation, Royal London Hospital, London, United Kingdom, ³HBP and Transplant Unit, Tor Vergata University, Rome, Italy
*Purpose: DGF after kidney transplantation (KTx) has been associated with an increased risk of rejection. For this reason, clinical guideline recommends weekly allograft biospy (Bx)…
2020 American Transplant Congress
A Single-Center Characterization of the Living Liver Donor Evaluation Process
L. R. Herbst, A. D. Love, M. Krach, Y. Yu, L. Kurman, A. Gurakar, M. Hammami, A. M. Cameron, J. Garonzik Wang
Department of Surgery, Johns Hopkins University, Baltimore, MD
*Purpose: We have previously characterized the living kidney donor evaluation and found that African American (AA) donors were less likely to progress through the process…
2020 American Transplant Congress
Maintenance Belatacept Therapy is Associated with Increased Rates of Polyoma Viremia
D. Conti, E. Maciera, D. Pluckrose, M. Garner, D. Schuster, S. Patel
Albany Medical Center, Albany, NY
*Purpose: The introduction of belatacept costimulatory blockade therapy has added a novel and powerful agent to the immunosuppressive armamentarium utilized after renal transplantation. However, limited…