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American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    ATHENA – Patient and Allograft Outcome Differences after Kidney Transplantation – Germany vs. France

    F. Thaiss1, C. Sommerer1, B. Suwelack1, D. Dragun1, I. A. Hauser1, O. Witzke1, C. Hugo1, P. Schenker1, N. Kamar2, P. Merville2, I. Kroeger3, M. Junge3, B. Nashan1

    1Athena, Study Group, Germany, 2Athena, Study Group, France, 3Novartis Pharma GmbH, Nürnberg, Germany

    *Purpose: In the ATHENA trial [NCT01843348], efficacy and safety of everolimus in combination with tacrolimus [EVR+TAC] or cyclosporine A [EVR+CyA] vs. TAC and mycophenolic acid…
  • 2020 American Transplant Congress

    The Influence of the Donor Kidney Weight to Recipient Body Weight Ratio on Long-Term Renal Graft Outcomes

    S. Yang1, J. Lee1, Y. Jung2, B. Kim3, M. Kim1, S. Kim1, Y. Kim1, K. Huh1

    1Department of Transplantation Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of, 3Department of Nephrology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: To study the impact of the relative donor kidney size on long-term graft function and survival, we investigated the living donor renal transplants outcomes.*Methods:…
  • 2020 American Transplant Congress

    Health-Related Quality of Life after Anonymous Nondirected Living Liver Donation: A Multi-Center, North American Collaboration

    M. H. Raza1, W. E. Jackson2, A. Dell3, L. Ding4, J. Shapiro3, E. A. Pomfret5, Y. Genyk6, L. Sher6, J. Emamaullee6

    1Keck School of Medicine of USC, Los Angeles, CA, 2Gastroenterology, University of Colorado, Aurora, CO, 3Surgery, University of Alberta, Edmonton, AB, Canada, 4Preventive Medicine, University of Southern California, Los Angeles, CA, 5Surgery, University of Colorado, Aurora, CO, 6Surgery, University of Southern California, Los Angeles, CA

    *Purpose: Literature on anonymous or ‘altruistic’ nondirected living liver donors (ND-LLDs) remains sparse as living donor liver transplant (LDLT) programs continue to explore the utilization…
  • 2020 American Transplant Congress

    Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation

    J. L. Saullo, A. Ferrari, E. M. Eichenberger, J. M. Steinbrink, A. W. Baker, M. Bacchus, E. K. Maziarz, S. Kakoullis, L. Zaffiri, H. Berry, J. M. Reynolds, C. R. Wolfe

    Duke University Medical Center, Durham, NC

    *Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…
  • 2020 American Transplant Congress

    Proposed New Pancreas Allocation Policy: Moving to Concentric Circles as First Unit of Allocation

    A. Israni1, S. Gustafson1, B. Thompson1, A. Wey1, S. Niederhaus2, R. Forbes3, A. Fox4, B. Kasiske1, J. Snyder1

    1SRTR, Minneapolis, MN, 2Univ of Maryland, Baltimore, MD, 3Vanderbilt Univ, Nashville, TN, 4UNOS, Richmond, VA

    *Purpose: The Organ Procurement and Transplantation Network (OPTN) proposed a new national deceased donor pancreas allocation policy that removes donor service area and OPTN region…
  • 2020 American Transplant Congress

    Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation

    H. Hirao1, T. Ito1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, R. W. Busuttil1, F. M. Kaldas1, J. W. Kupiec‐Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
  • 2020 American Transplant Congress

    Pancreatic Mesenchymal Stromal Cells (MSC) Contain a Subset of Islet Progenitor Cells Capable of Regenerating Islets and Reversing Diabetes

    C. M. Darden1, S. Vasu2, K. Kumano1, Y. Liu2, P. Saravanan3, B. Naziruddin2, M. Lawrence2

    1Institute of Biomedical Studies, Waco, TX, 2Baylor University Medical Ctr, Dallas, TX, 3Transplant Surgery Department, VCU, Richmond, VA

    *Purpose: To identity islet precursor cells residing in pancreatic MSC culture preparations that contribute to islet regeneration and restoration of islet cell function in both…
  • 2020 American Transplant Congress

    Early Experience Transplanting Undocumented Immigrants with ESRD at a Single Institution: Outcomes and Challenges

    R. T. Christie1, R. M. Nygaard2, C. J. Richardson1, M. J. Hill1, T. Anderson-Haag3, A. Israni4, P. A. Stahler1

    1Transplant Surgery, Hennepin Healthcare, Minneapolis, MN, 2Surgery, Hennepin Healthcare, Minneapolis, MN, 3Transplant Pharmacy, Hennepin Healthcare, Minneapolis, MN, 4Nephrology, Hennepin Healthcare, Minneapolis, MN

    *Purpose: In July of 2016, Minnesota became the second state in the nation to provide coverage for kidney transplantation to patients, regardless of immigration status,…
  • 2020 American Transplant Congress

    Fate of Donor-Derived Regulatory Dendritic Cells (DCreg) and Augmentation of Host Regulatory T Cells Following Their Infusion Into Prospective Living-Donor Liver Transplant Recipients

    A. W. Thomson, C. Macedo, A. F. Zahorchak, X. Gu, A. Humar, F. G. Lakkis, M. A. Styn, D. M. Metes

    Starzl Transplantation Institute, Pittsburgh, PA

    *Purpose: Our purpose was to ascertain the fate of ex vivo-generated donor-derived DCreg and their influence on host T cells prior to transplant in a…
  • 2020 American Transplant Congress

    The Liver Outcome Monitoring Registry Donor Risk Index: A New Measure of Deceased Donor Liver Quality

    S. Kurian1, J. Case1, A. Robinson2, B. Barrick1, M. Prentice2, C. Marsh1

    1Scripps Center for Organ and Cell Transplantation, La Jolla, CA, 2United Network for Organ Sharing Research Department, Richmond, VA

    *Purpose: The liver donor risk index (LDRI) created in 2006 evaluated the relative risk of graft failure, however its weaknesses have limited its use in…
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