ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease

    K. J. Yang1, M. Martinez2, B. Shonts1, C. A. Parks1, A. Z. Obradovic1, T. M. Savage1, E. Spyrou1, S. Lau1, M. I. Colquhoun1, K. Rodgers1, E. Verna3, S. M. Coley4, S. Yang1, Y. Shen5, M. Sykes1

    1Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, 2Department of Pediatrics, Columbia University, New York, NY, 3Department of Medicine, Columbia University, New York, NY, 4Department of Pathology, Columbia University, New York, NY, 5Center for Computational Biology & Bioinformatics, Department of Systems Biology, Columbia University, New York, NY

    *Purpose: Patients who undergo liver transplantation for autoimmune liver disease (ALD) experience high rates of graft failure. The relative roles of recurrent ALD and rejection…
  • 2020 American Transplant Congress

    Belatacept Combined with BTLA Prolong Allogeneic Kidney Graft Survival and Inhibited Acute Rejection after Kidney Transplantation

    H. Zhang, Z. Wang, J. Zhang, Z. Han, J. Tao, H. Chen, L. Sun, R. Tan, M. Gu

    Jiangsu Province Hospital, Nanjing, China

    *Purpose: Belatacept as a high-affinity variant of CTLA-4Ig, has been applied into kidney transplantation to against acute rejection. However, adoption of Belatacept has been limited…
  • 2020 American Transplant Congress

    Real-Time Viability Assessment During Normothermic Machine Perfusion with Resonance Raman Spectroscopy

    R. J. De Vries1, S. Raigani1, P. Romfh2, S. E. Cronin1, C. A. Pendexter1, C. Carroll1, T. M. Van Gulik3, P. Chen2, K. Uygun1, H. Yeh1, S. N. Tessier1

    1Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 2Pendar Technologies, Cambridge, MA, 3Surgery, Amsterdam University Medidical Centers, Location AMC, Amsterdam, Netherlands

    *Purpose: Viability assessment during normothermic machine perfusion (NMP) continues to lack objective metrics that facilitate accurate clinical decision making, in order to minimize discard rates…
  • 2020 American Transplant Congress

    Humoral Sensitization Overrides Pregnancy-Induced T Cell Transplantation Tolerance

    D. Tran1, A. Suah1, S. Khiew1, J. Young1, M. Andrade1, J. Pollard1, Q. Wang1, D. Yin1, G. Chalasani2, M. Alegre1, A. Chong1

    1Department of General Surgery, University of Chicago, Chicago, IL, 2Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: There are ample clinical data that a major long-term consequence of pregnancy is humoral allosensitization. Paradoxically, pregnancy is also a state of spontaneous allogeneic…
  • 2020 American Transplant Congress

    Long Term Outcomes of Hypertensive Kidney Donors

    H. Ibrahim, S. Hebert, H. E. Adrogue, D. T. Nguyen, E. A. Graviss, A. Gaber, A. Matas

    Houston Methodist Hospital, Houston, TX

    *Purpose: Many people with hypertension are excluded from kidney donation fearing that hypertension is a major cause of CKD and its impact maybe magnified after…
  • 2020 American Transplant Congress

    One Organ Procurement Organization Coordinates 43% of All Uncontrolled Donation after Circulatory Determination of Death Donors Recovered in the United States Over 24 Years

    R. D. Hasz, S. M. West, H. M. Nathan

    Gift of Life Donor Program, Philadelphia, PA

    *Purpose: An IOM report published in 2006 estimated that 22,000 potential uncontrolled Donation after Circulatory Determination of Death (uDCDD) donors die each year in the…
  • 2020 American Transplant Congress

    Association between Area-Level Measures of Deprivation and Readiness to Pursue Living Donor Kidney Transplant

    M. A. Saqib, A. Li, J. Hussain, Q. Wang, N. El-Dassouki, A. Dychiao, L. Angarso, N. Edwards, M. Novak, I. Mucsi

    University Health Network, Toronto, ON, Canada

    *Purpose: This study aims to assess if material deprivation is associated with readiness to pursue living donor kidney transplant (LDKT)*Methods: A cross-sectional sample of adults…
  • 2020 American Transplant Congress

    Determinants of Cardiovascular Benefit Observed in a Population with a Functioning Renal Transplant versus Patients Undergoing Chronic Dialysis

    J. Sleiman, C. Castellaro, G. Laham, M. Schiavone, M. Biain, L. Brukman, G. Soler Pujol, C. Diaz

    Nephrology, CEMIC, Caba, Argentina

    *Purpose: Patients (pts) with end stage renal disease have a high morbidity and mortality rate, mostly due to cardiovascular events (CV). Transplantation (Tx) improves survival…
  • 2020 American Transplant Congress

    Yield and Utility of Surveillance Kidney Biopsies in Pediatric Kidney Transplant Recipients at Various Time Points Post-Transplant

    A. Landsberg1, M. Riazy2, T. Blydt-Hansen1

    1Nephrology, BC Children's Hospital, Vancouver, BC, Canada, 2Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, BC, Canada

    *Purpose: There lacks consensus regarding the appropriate timing of routine surveillance biopsies (SB) for pediatric kidney transplant recipients. We evaluated the yield of positive biopsy…
  • 2020 American Transplant Congress

    Multi- National Survey among Nephrologists & Transplant Surgeons about the Suitability & Acceptance of the Marginal Living- Kidney Donors with Obesity or Abnormal Blood Sugar Profile

    Z. Arabi1, M. A. Bukhari2

    1KAMC, Riyadh, Saudi Arabia, 2Taif University, Taif, Saudi Arabia

    *Purpose: There are no clear guidelines about the suitability and acceptance of living- kidney donors with obesity or abnormal blood sugar profile.*Methods: To form a…
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