Am J Transplant, Volume 20, Suppl 3 Archives - Page 68 of 223 - ATC Abstracts

2020 American Transplant Congress
Bone Marrow Plasma Cell Heterogeneity Drives Resistance of Proteasome Inhibitor Therapy
C. M. Castro-Rojas¹, S. Tremblay², J. Driscoll³, K. Roskin⁴, R. R. Alloway³, E. Woodle², D. A. Hildeman¹
¹Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH, ²Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, ³Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH
*Purpose: Patients sensitized to HLA antigens by prior transplantation, pregnancy or blood transfusion may have markedly prolonged waiting times for transplant. Moreover, once transplanted, the…
2020 American Transplant Congress
Liver Transplantation with Grafts from Super Obese Donors with a BMI>50
P. Vargas¹, J. M. Cullen¹, P. Northup², J. Oberholzer¹, S. Pelletier¹, N. Goldaracena¹
¹Department of Surgery, Division of Transplantation, University of Virginia Health System, Charlottesville, VA, ²Department of Medicine-Gastroenterology, University of Virginia Health System, Charlottesville, VA
*Purpose: Organ shortage is aggravated by an obesity epidemic. There is limited data on liver transplant (LT) outcomes from liver grafts originating from super obese…
2020 American Transplant Congress
Left Lobe Living Donor Liver Transplantation Using Rapid Procedure in a Cirrhotic Patient with Hepatocellular Carcinoma with a GRWR of 0.35
D. Balci¹, O. Kirimker¹, M. Kologlu², U. Goktug¹, E. Ustuner³, S. Karadag⁴, E. Er⁵, G. Cinar⁶, M. Bayar⁴, A. Yilmaz⁴, A. Azap⁶, K. Karayalcin¹
¹General Surgery and Transplantation, Ankara University, Ankara, Turkey, ²Pediatric Surgery and Transplantation, Ankara University, Ankara, Turkey, ³Radiology, Ankara University, Ankara, Turkey, ⁴Anesthesiology, Ankara University, Ankara, Turkey, ⁵Gastroenterology, Ankara University, Ankara, Turkey, ⁶Infectious Disease, Ankara University, Ankara, Turkey
*Purpose: Here, we describe a new approach using Rapid Procedure, a 2 stage hepatectomy technique, with living donor liver transplantation (LDLT) in the cirrhotic setting…
2020 American Transplant Congress
New Concept of Liver Transplatation in Pediatric Patient – Up Side Down Metod
P. Dubska, L. Janousek, J. Chlupac, M. Kocik, J. Fronek
Transplantation Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Liver transplantation (LTx) in pediatrics has become an accepted modality for treatment in end-stage liver disease and irreversible acute liver failure. Left lateral segment…
2020 American Transplant Congress
Efficacy of Single-Strength Trimethoprim-Sulfamethoxazole Thrice Weekly for Pneumocysitis Jirovecii Pneumonia Prophylaxis Post Liver Transplantation
A. Puing, A. Subramanian
Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA
*Purpose: Current guidelines recommend Pneumocystis jirovecii pneumonia (PJP) prophylaxis for at least 6-12 months after liver transplant (LTx) with preferably Trimethoprim-sulfamethoxazole (TMP-SMX) at a daily…
2020 American Transplant Congress
Transplanting Livers from Hepatitis C Virus Positive Donors; Is it Worth the Risk?
J. W. Mensink¹, B. Van Hoek², B. Schaefer³, M. D. Van Rosmalen⁴, I. P. Alwayn⁵, A. E. Braat⁵
¹Leiden University Medical Center, Leiden, Netherlands, ²Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands, ³Dutch Transplant Foundation, Leiden, Netherlands, ⁴Eurotransplant International Foundation, Leiden, Netherlands, ⁵Transplant Surgery, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Before the introduction of Direct-Acting Antivirals (DAAs), only selected organs from Hepatitis C virus (HCV) positive donors were successfully transplanted into HCV positive recipients.…
2020 American Transplant Congress
Management of Pancreatic Cancer after Liver Transplantation: A 27-Year Single-Center Experience
I. A. Ziogas, M. A. Rauf, L. K. Matsuoka, M. I. Montenovo, M. Izzy, S. P. Alexopoulos
Vanderbilt University Medical Center, Nashville, TN
*Purpose: The occurrence of de novo cancer after liver transplant (LT) is a leading cause of post-LT mortality and can be partially attributed to the…
2020 American Transplant Congress
Successful Transplantation of Murine Hearts Preserved 24h Under Subzero Ischemia Using Novel Bio-Inspired Next Generation Cryoprotectants
B. Oh¹, A. Callegari², M. Kline², A. Childs², M. Iglesias Lozano¹, G. Brandacher¹, X. Wei²
¹Department of Plastic and Reconstructive Surgery, Vascularized Composite Allotransplantation (VCA), Johns Hopkins University School of Medicine, Baltimore, MD, ²X-Therma Inc., Richmond, CA
*Purpose: Extension of the organ ischemia window is of paramount importance to prolong viability of transplantable organs and to improve overall outcomes. Transport using a…
2020 American Transplant Congress
The Effects of Rivaroxaban and Apixaban on Tacrolimus Pharmacokinetics
A. C. Scheibner¹, C. Franco-Martinez¹, E. Kincaide¹, R. Hall¹, C. Long²
¹Pharmacotherapy Division, College of Pharmacy, The University of Texas at Austin, University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Feik School of Pharmacy, University of the Incarnate Word, University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: To clarify the pharmacokinetic impact of rivaroxaban (RIVA) and apixaban (APIX) on tacrolimus (TAC) concentrations.*Methods: Solid organ transplant recipients 18-years or older who were…
2020 American Transplant Congress
Envarsus XR Use Can Benefit Serum Creatinine Levels in Vascularized Composite Allotransplantation Patients
C. M. Cooney¹, V. Javia¹, J. Littleton¹, D. S. Cooney¹, R. J. Redett¹, J. T. Shores¹, D. C. Brennan², G. Brandacher¹
¹Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ²Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Vascularized composite allotransplantation (VCA) is a life-enhancing (as opposed to life-saving) procedure. Therefore, minimizing adverse outcomes associated with chronic immunosuppression is vital to determining…