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American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Recurrent Lupus Post Kidney Transplantation- The Histological and Clinical Characteristics

    A. Bentall1, W. Jiqiu2, A. Kattah1, M. L. Gonzalez Suarez3, F. G. Cosio1, M. Mai4, H. Khamash5, M. D. Stegall6, H. Amer1, L. D. Cornell7, F. Fervenza1, M. P. Alexander7

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 2National Clinical Research Center of Kidney Diseases, Nanjing University, Nanjing, China, 3Department of Nephrology, University of Mississippi Medical Center, Jackson, MS, 4Division of Nephrology and Hypertension, Mayo Clinic, Jackonville, FL, 5Division of Nephrology and Hypertension, Mayo Clinic, Scottdale, AZ, 6Department of Transplant Surgery, Mayo Clinic, Rochester, MN, 7Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

    *Purpose: Lupus nephritis (LN) progresses to ESRD in
  • 2020 American Transplant Congress

    Offspring to Parent Living Donor Liver Transplantation: An Analysis of the A2ALL Database

    R. A. Choudhury1, H. J. Braun2, J. D. Grab2, J. L. Dodge2, H. B. Moore1, D. Yoeli1, J. J. Pomposelli1, T. Nydam1, N. L. Ascher2, E. A. Pomfret1, J. P. Roberts2

    1Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2Department of Surgery- Division of Transplantation Surgery, University of California, San Francisco, San Francisco, CA

    *Purpose: Recently, there have been concerns regarding inferior graft survival following offspring to parent kidney transplantation due to issues related to alloimmunity during pregnancy. It…
  • 2020 American Transplant Congress

    Reduced Dose Valganciclovir is Effective for CMV Prevention without Excess Breakthrough or Resistance in Kidney Transplantation

    M. Luu1, P. Klem1, B. Crowther1, M. Abidi2, M. Miller1, K. Schoeppler1, S. Davis2

    1Pharmacy, University of Colorado Hospital, Aurora, CO, 2Medicine, University of Colorado, Aurora, CO

    *Purpose: Reduced dose valganciclovir (VGC) (450 mg daily) may be a useful alternative to full dose VGC for cytomegalovirus (CMV) prophylaxis due to drug cost…
  • 2020 American Transplant Congress

    Calculating the Lung Allocation Score Error for ECMO Patients

    N. Dussault1, J. Katsis2, E. Garrity1, M. M. Churpek3, W. F. Parker1

    1University of Chicago, Chicago, IL, 2Vanderbilt University, Nashville, TN, 3University of Wisconsin, Madision, WI

    *Purpose: The use of extracorporeal membranous oxygenation (ECMO) as a bridge to lung transplantation has increased dramatically. However, the Lung Allocation Score (LAS) does not…
  • 2020 American Transplant Congress

    Preformed Donor Specific Antibody and Mfi-Dependent Effects in Simultaneous Liver-Kidney Transplantation

    V. Fleetwood, C. Papageorge, D. Aufhauser, G. Leverson, B. Welch, L. Hidalgo, D. Foley, Y. Yankol, A. D'Alessandro, D. Al-Adra, R. Redfield, J. Mezrich

    Department of Transplantation, University of Wisconsin, Madison, WI

    *Purpose: Preformed donor specific antibody to HLA Class II (pDSA) is suggested to be an independent risk factor for mortality in simultaneous liver and kidney…
  • 2020 American Transplant Congress

    Generation of Insulin-Producing Cells via Multiplex Epigenetic Engineering of Human Somatic Cells in 2 Weeks

    R. A. Naqvi1, W. Zhang1, A. Isidan1, C. Evans-Molina2, J. A. Fridell1, P. Li1, B. Ekser1

    1Division of Transplant Surgery, Indiana University, Indianapolis, IN, 2Diabetes Research Center, Indiana University, Indianapolis, IN

    *Purpose: Stem cell-derived β-cells not only promise a renewable supply of insulin-producing cells with negligible immunosuppression but may also provide a substrate for the identification…
  • 2020 American Transplant Congress

    Initial North American Experience in Renal Transplantation from Medical Assistance in Dying Donors

    M. A. Levine, S. Sami, A. Sener, P. Luke

    Surgery, London Health Sciences Centre, London, ON, Canada

    *Purpose: In 2016, Canadian federal legislation was passed creating a regulatory framework for medical assistance in dying (MAiD) for individuals who are suffering from a…
  • 2020 American Transplant Congress

    Long-Term Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Living Donor Renal Transplant Recipients

    J. Leventhal1, J. Mathew1, J. Galvin2, L. Gallon1, D. Belshe1, K. Ravindra3, M. Horwitz3, J. Miller1, S. Ildstad4

    1Northwestern, Chicago, IL, 2UIC, Chicago, IL, 3Duke, Durham, NC, 4U Louisville, Louisville, KY

    *Purpose: 37 pts have been transplanted since 2009 in a phase 2 protocol to induce tolerance in recipients of living donor renal allografts (KTx). The…
  • 2020 American Transplant Congress

    Identifying Optimal Recipients for DCD Livers: Minimizing Risks of Liver Transplantation with DCD Livers by Matching to Preferred Recipients

    K. R. Jackson, J. Motter, A. Massie, J. Garonzik-Wang, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Donation after cardiac death (DCD) livers represent a possible expansion to the donor pool, but are frequently discarded as they are associated with a…
  • 2020 American Transplant Congress

    Molecular Diagnosis and Risk Prediction in BK Virus Nephropathy: Discovery and Multicenter Validation of Novel Intragraft Gene Expression Signatures

    B. Adam1, Z. Kikic2, Y. Bouatou3, J. Gueguen3, B. Robin3, G. Reid1, H. Regele2, M. Rabant3, A. Loupy3, M. Mengel1

    1University of Alberta, Edmonton, AB, Canada, 2Medical University of Vienna, Vienna, Austria, 3Paris Transplant Group, Paris, France

    *Purpose: Novel tools are needed to improve diagnosis and risk prediction in BK virus nephropathy (BKVN). This study aimed to assess the utility of intragraft…
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