Am J Transplant, Volume 20, Suppl 3 Archives - Page 61 of 223 - ATC Abstracts

2020 American Transplant Congress
Long-Term Metabolic Control and Health Outcomes in Maple Syrup Urine Disease Following Liver Transplantation in Children and Young Adults
C. Ewing¹, K. Soltys², K. Strauss³, G. Mazariegos², R. Sindhi², J. Vockley², P. McKiernan², R. Squires², G. Bond², A. Khanna², J. Squires²
¹School of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA, ³Clinic for Special Children, Strausburg, PA
*Purpose: Determine outcomes and branch-chain amino acid (BCAA - leucine [LEU], isoleucine [ISO], and valine [VAL]) levels at 1-3, 4-7, and 8-10 years for patient’s…
2020 American Transplant Congress
Combining Pharmacy and Genome-Wide Genotyping Data to Examine Medication Regimen Complexity Indices (MRCI), Drug-Drug and Gene-Drug Interactions in Transplant Patients
L. Callans, J. Obayemi, H. Gao, A. Shaked, B. Chang, B. Keating
Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, USA, Philadelphia, PA
*Purpose: Polypharmacy, typically defined as the use of five or more medications, is a barrier to adherence, and the resulting complex medication regimens result in…
2020 American Transplant Congress
The Impact of DSA Screening in Stable Kidney Transplant Recipients in the 1st Year Post-Transplant
A. Sharma¹, D. Jorgensen², R. Mehta¹, P. Sood¹, C. Wu¹, C. M. Puttarajappa¹, A. Tevar¹, S. Hariharan¹
¹Thomas E. Starzl Transplant Institute, Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Thomas E. Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The importance of Donor Specific Antibody (DSA) as a screening tool within the 1st year post kidney transplant in stable patients remains unclear. We…
2020 American Transplant Congress
Allograft Parenchymal Cell Expression of Tlr9 is Required for Endogenous Donor-Reactive Memory Cd8 T Cell Activation within High-Risk Cardiac Allografts to Mediate Ctla-4 Ig Resistant Graft Rejection
D. Ueda, H. Tsuda, S. Miyairi, R. L. Fairchild
Lerner Reserch Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Increased ischemia-reperfusion graft inflammation provokes activation of endogenous donor-reactive memory CD8 T cells within complete MHC-mismatched cardiac allografts at 24 hrs after graft reperfusion…
2020 American Transplant Congress
Are HLA-DQ De Novo Donor-Specific Antibodies a Risk Factor for Acute Humoral Rejection?
R. Hod Dvorai¹, C. A. Hubbell¹, M. R. Laftavi², R. Shahbazov², B. Gallay³, O. G. Pankewycz³
¹Pathology, SUNY Upstate Medical University, Syracuse, NY, ²Surgery, SUNY Upstate Medical University, Syracuse, NY, ³Medicine, SUNY Upstate Medical University, Syracuse, NY
*Purpose: To identify HLA-DQ de novo donor-specific antibodies (dnDSA) characteristics associated with acute humoral rejection (ABMR) and response to treatment.*Methods: We performed a retrospective analysis…
2020 American Transplant Congress
Measuring Environmental Elemental Exposure in the Hair Allows to Identify Kidney Transplant Recipients at Risk of Acute Rejection
A. Angeletti¹, I. Gandolfini², C. Cantarelli², U. Maggiore², L. Gaetano¹, E. Fiaccadori², J. Reid-Adam³, J. Saland³, P. Curtin³, A. Curtin³, C. Austin³, P. Cravedi³
¹St. Orsola Hospital, University of Bologna, Bologna, Italy, ²Parma University, Parma, Italy, ³Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Most biomarkers are representative of a single moment in time, which, even when repeatedly assessed, may not capture trends or variability. Hair is a…
2020 American Transplant Congress
Changes in Body Composition One Year after Hand-Assisted Laparoscopic Donor Nephrectomy in Living Kidney Donors
H. Fukuhara¹, Y. Watarai¹, S. Narumi¹, N. Goto¹, T. Hiramitsu¹, M. Okada¹, K. Futamura¹, T. Tomosugi¹, A. Kanda¹, T. Nawano¹, N. Tsuchiya²
¹Department of Transplant Nephrology and Surgery, Nagoya Daini Red Cross Hospital, Myoukentyou, Japan, ²Department of Urology, Yamagata University Faculty of Medicine, Yamagata City, Iidanishi, Japan
*Purpose: The aim of this study was to investigate the effect of surgery on living donors’ body composition and to clarify the factors related to…
2020 American Transplant Congress
Incidence and Risk Factors of Post-Transplant Erythrocytosis in Deceased Donor Kidney Transplantation
S. Alasfar, Y. Jia, I. E. Hall, H. Thiessen Philbrook, S. G. Mansour, M. D. Doshi, S. Mohan, J. S. Bromberg, P. P. Reese, C. Parikh
DDS Consortium, Baltimore, MD
*Purpose: Post-transplant erythroytosis (PTE) is clinically important condition after kidney transplantation (KTx). Previously published literature from single-center studies, demonstrated variable incidence rates between 8-15%. We…
2020 American Transplant Congress
Social Determinants as Indicators for Medication Adherence and Graft Function in Pediatric Kidney Transplant Recipients
S. Craven, K. Clark, A. Feryn, S. Ponce, G. Laird, A. Al-Uzri
Oregon Health & Science Univ, Portland, OR
*Purpose: To examine the association of social determinants of health (SDoH), the conditions in which people are born and live, with medication adherence and graft…
2020 American Transplant Congress
An Evaluation of Converting Elderly Kidney Transplant Recipients from Tacrolimus to LCPT to Limit Neurological Adverse Events and Improve Quality of Life
A. Reticker, B. Valdepenas, K. Bruno, D. Cikopana, S. Walton, E. Benedetti, I. Tzvetanov, P. West-Thielke
University of Illinois, Chicago, IL
*Purpose: Adverse effects (AEs) of tacrolimus significantly reduce recipients’ quality of life (QOL). Given its ability for tremor improvement, this study investigates whether conversion from…