ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Tyrosine Receptor Kinase Axl Regulates Intragraft Trafficking of Alloreactive T Cells Post Kidney Transplantation

    A. Dangi1, K. Glinton2, M. Sharma1, S. Yu1, M. DeBerge2, E. B. Thorp2, X. Luo1

    1Nephrology/Medicine, Duke University, Durham, NC, 2Pathology, Northwestern University, Chicago, IL

    *Purpose: Previous studies have shown that receptor tyrosine kinase Axl, primarily expressed on dendritic cells and some tissue-specific macrophage population, is required for T cells…
  • 2020 American Transplant Congress

    Undernutrition and Hypoleptinemia Modulate Cytomegalovirus Infection

    E. David1, M. Zhu2, W. Parker2, N. MacIver1, A. D. Kirk2, E. T. Chambers1

    1Pediatrics, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC

    *Purpose: Cytomegalovirus (CMV) viremia/infection remains a significant cause of morbidity in transplantation, especially in the undernourished population. Undernutrition and hypoleptinemia have been implicated in other…
  • 2020 American Transplant Congress

    Treg Lymphotoxin Signals Promote Cancer Metastatic Migration: Mechanisms for Treg-Cancer Interaction

    W. Piao1, R. Oakes2, C. Paluskievicz1, Y. Xiong1, L. Li1, V. Saxena1, M. WillsonShirkey1, C. Jewell2, J. Bromberg1

    1Surgery, U of Maryland, Baltimore, MD, 2U of Maryland, College Park, MD

    *Purpose: Immune suppressive therapy can be complicated by malignancy. Regulatory T cells (Treg) control immune tolerance for graft survival but cause to immune suppression in…
  • 2020 American Transplant Congress

    Clinical Outcomes Associated with Long-Term Exposure to Airborne Particulate Pollution in Kidney Transplant Recipients

    Y. Kim1, J. Lee2

    1Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of

    *Purpose: We aimed to evaluate the relationship of 10-μm particulate matter (PM10) with the risk of graft failure, mortality, and decline of graft function in…
  • 2020 American Transplant Congress

    Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates

    A. Kardashian1, J. Ge1, C. McCulloch1, M. R. Kappus2, M. A. Dunn3, A. Duarte-Rojo3, M. L. Volk4, R. S. Rahimi5, E. C. Verna6, D. R. Ganger7, D. Ladner7, J. L. Dodge1, B. Boyarsky8, M. McAdams-DeMarco8, D. L. Segev8, J. C. Lai1

    1UCSF, SF, CA, 2Duke, Durham, NC, 3UPMC, Pittsburgh, PA, 4LLU, Loma Linda, CA, 5BSWH, Dallas, TX, 6Columbia, NY, NY, 7Northwestern, Chicago, IL, 8JHMI, Baltimore, MD

    *Purpose: Frailty is associated with mortality in liver transplant (LT) waitlist candidates. We developed the Liver Frailty Index (LFI) to assess frailty in patients with…
  • 2020 American Transplant Congress

    Improving DRG Based Reimbursement to Reflect Complexity of Kidney Transplant

    I. R. Schwantes1, M. Schnitzler2, K. Lentine2, A. Reed1, D. A. Axelrod3

    1Surgery, University of Iowa, Iowa City, IA, 2Saint Louis University, St. Louis, MO, 3Surgery, Universtiy of Iowa, Iowa City, IA

    *Purpose: More than 90,000 individuals await a kidney transplant (KTx) in the US, yet up to 20% of recovered kidneys are discarded. Organ Transplant Centers…
  • 2020 American Transplant Congress

    Thymoglobulin (ATG) Induction vs. Campath vs. Simulect in DCD Kidneys in UK; Induction Regimes Play a Role after All

    A. Asderakis1, T. Sabbah1, J. Watkins2, L. Szabó1, D. Elker1, A. M. Ilham1, E. Ablorsu1, M. Stephens1, U. Khalid1, R. Chavez1

    1Cardiff Transplant Unit,, University Hospital of Wales, Cardiff, United Kingdom, 2Infection and Immunity, Cardiff University, Cardiff, United Kingdom

    *Purpose: Controlled DCD kidneys have increased dramatically in UK. They suffer from a higher rate of DGF and, often in UK, come from older donors…
  • 2020 American Transplant Congress

    Long Term Graft Outcome after Subclinical Banff Borderline Changes Suspicious for Acute T Cell-Mediated Rejection

    A. Han, H. Ko, C. Chung, H. Kim, S. Min, J. Ha

    Seoul National University College of Medicine, Seoul, Korea, Republic of

    *Purpose: Long term data after Banff borderline changes suspicious for acute T cell-mediated rejection (BDR lesion) are scarce, and hence, there is little evidence to…
  • 2020 American Transplant Congress

    Short Recipient Warm Ischemia Time Improves Graft Survival in Liver Transplantation from Donation after Brain Death: 20-Year Experience of Liver Transplantation

    A. Al-Kurd, T. Kitajima, K. Delvecchio, A. M. Elsabbagh, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, S. Nagai

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    *Purpose: Although the correlation between warm ischemia time (WIT) and the outcomes of liver transplantation has been extensively studied, few investigations have focused on the…
  • 2020 American Transplant Congress

    Increasing Prevalence and Diversity: Alcoholic Liver Disease in Liver Transplant Candidates

    M. Joshi, E. L. Godfrey, J. A. Goss, A. Rana

    Baylor College of Medicine, Houston, TX

    *Purpose: Increasing global alcohol use translates to a marked growth in alcoholic liver disease (ALD). ALD patients comprise a larger proportion of listings for liver…
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