ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Clinical Significance of C1q+ Antibodies in Pediatric Kidney Transplant Recipients

    N. Hayde1, S. Solomon2, A. Colovai1

    1Montefiore Medical Center, Bronx, NY, 2Westchester Medical Center, Valhalla, NY

    *Purpose: To evaluate the impact of denovo DSA (C1q+ vs C1q-) on graft outcomes in pediatric kidney transplant recipients.*Methods: Children transplanted between 2009 and 2016…
  • 2020 American Transplant Congress

    Mortality Index Should Be Used to Provide Realistic Expectations Regarding Transplant Candidacy

    Y. Chalicheemala1, K. Chavin2, T. Srinivas1, A. Padiyar1

    1Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Renal transplant improves outcomes of well-selected elderly patients with end stage renal disease. Older patients with significant comorbidities may not live long enough to…
  • 2020 American Transplant Congress

    Peer Feedback Improves Nephrologists’ Transplant Referral Practices

    A. Padiyar, T. Srinivas

    Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: While preemptive kidney transplant is associated with superior outcomes, timely referral remains a significant barrier. Peer feedback may help improve practice. Our hypothesis is…
  • 2020 American Transplant Congress

    Changes in Health-Related Quality of Life During the First Year in Lung Transplantation Recipients

    H. Zhou, J. Chen

    Lung Transplant Center, Wuxi People’s Hospital, Wuxi, China

    *Purpose: This longitudinal study was conducted to recognize the tracks of HRQOL during the first year after transplantation and the main factors associated with HRQOL…
  • 2020 American Transplant Congress

    Single Cell Profiling of PBMC Identifies Immune Populations Associated with High Risk of Early Acute Rejection

    W. Zhang, S. Farouk, Z. Sun, W. Huang, Z. Yi, J. Fu, C. Wei, M. Fribourg-Casajuana, C. He, P. Cravedi, B. Murphy

    Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: Our previous transcriptomic analysis of pre-transplant peripheral blood revealed a 23-gene set predictive of early acute rejection (EAR) post kidney transplant (JCI Insight, 2019).…
  • 2020 American Transplant Congress

    Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity after Switch to Belatacept-Based Regimen after Kidney Transplantation

    J. Schaenman, M. Rossetti, H. Wilhalme, V. Groysberg, G. Sunga, J. Gadzhyan, B. Abdalla, E. Lum, P. Pham, G. Danovitch, J. Veale, H. A. Gritsch, D. Elashoff, E. Reed, S. Bunnapradist

    David Geffen School of Medicine at UCLA, Los Angeles, CA

    *Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.*Methods: 19 patients with evidence of calcineurin inhibitor (CNI) toxicity…
  • 2020 American Transplant Congress

    Clinical Significance of T Cell and B Cell Epitope Prediction as a Risk Factor of De Novo DSA Production after Kidney Transplantation

    T. Kobayashi1, K. Iwasaki1, T. Tomosugi2, Y. Miwa1, M. Niemann3, E. Spierings4, K. Horimi1, Y. Matsuoka1, A. Takeda2, N. Goto2, S. Narumi2, Y. Watarai2

    1Aichi Medical University School of Medicine, Nagakute, Japan, 2Nagoya Daini Red Cross Hospital, Nagoya, Japan, 3PIRCHE AG, Berlin, Germany, 4UMC Utrecht, Utrecht, Netherlands

    *Purpose: Chronic antibody-mediated rejection caused by de novo DSA (dnDSA) is a major cause of graft failure. Risk prediction of dnDSA would be important for…
  • 2020 American Transplant Congress

    Predictors of Estimated GFR and Recurrent Chronic Kidney Disease (CKD) after Simultaneous Liver and Kidney Transplantation (SLKT): Results from the US Multicenter SKLT Consortium

    P. Sharma1, Z. Sui1, M. Zhang1, J. Magee1, P. Barman2, Y. Patel3, K. Walters4, S. Biggins5, A. Schluger6, G. Cullaro7, R. Wong8, J. Lai8, J. Jo9, J. Sinha9, L. VanWagner9, E. Verna7

    1Michigan Medicine, Ann Arbor, MI, 2UCSD, San Diego, CA, 3Duke, Durham, NC, 4UCLA, LA, CA, 5University of Washington, Seattle, WA, 6Westchester Medical Center, Weschester, NY, 7Columbia, New York, NY, 8UCSF, San Francisco, CA, 9Northwestern, Chicago, IL

    *Purpose: SLKT is a life-saving intervention for patients with decompensated cirrhosis and concomitant end stage renal disease, irreversible acute kidney injury and select inherited metabolic…
  • 2020 American Transplant Congress

    Gut Commensal Microbiota are Associated with a Decreased Risk for Enterobacteriaceae Bacteriuria

    J. R. Lee1, M. Magruder1, L. Zhang1, D. Dadhania1, E. Edusei1, S. Albakry1, M. Lubetzky1, E. Pamer2

    1Medicine / Nephrology and Hypertension, Weill Cornell Medicine, New York, NY, 2University of Chicago, Chicago, IL

    *Purpose: Uropathogens from the gut is thought to be a source of bacteriuria and urinary tract infection, but the role of gut commensal microbiota in…
  • 2020 American Transplant Congress

    Ethical Considerations and Post-Operative Outcomes in Good Samaritan Living Liver Donors: What Motivates Individuals to Donate to Strangers

    C. Flaig, A. Humar, E. Kirschner, C. Hughes, S. Ganesh, A. Tevar, J. Steel

    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: Few transplant centers evaluate Good Samaritan living liver donors, secondary to ethical concerns and lack of evidence that the post-operative outcomes are comparable to…
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