Am J Transplant, Volume 20, Suppl 3 Archives - Page 56 of 223 - ATC Abstracts

2020 American Transplant Congress
Perfusion Regulated Organ Therapeutics with Enhanced Controlled Testing (PROTECT): Novel Human Model to Mitigate Ischemia-Reperfusion Injury in Liver Transplant
M. Nazzal, E. Madsen, M. Nguyen, A. Welu, H. Madnawat, C. Manithody, C. Denton, D. Blackall, D. Carpenter, J. Teckman, C. Varma, A. Jain
Saint Louis University, Saint Louis, MO
*Purpose: Despite a global organ shortage, there is almost a 10% discard rate of ‘marginal donor livers’ (MDL), deemed unsuitable for transplantation due to the…
2020 American Transplant Congress
Blocking Complement Component C3 in a Sensitized Nonhuman Primate Model of Kidney Allotransplantation
R. Schmitz¹, P. M. Schroder¹, Z. W. Fitch¹, A. Y. Choi¹, M. Manook¹, J. Yoon¹, A. Farris², E. S. Reis³, J. D. Lambris³, J. Kwun¹, S. J. Knechtle¹
¹Department of Surgery, Duke University Medical Center, Durham, NC, ²Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, ³Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
*Purpose: Sensitized transplant recipients represent a challenge due to the presence of donor-specific antibodies (DSA), which increase the risk of antibody-mediated rejection. Complement inhibition has…
2020 American Transplant Congress
Introduction of Preemptive Pharmacogenomic Testing in Kidney Transplant Recipients: Early Evaluation of the Clinical Impact of Genomic Guided Tacrolimus Dosing
G. Girone¹, V. Do¹, K. Belfield¹, R. Pulk¹, E. Cohen¹, E. Marin²
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, ²Department of Nephrology, Yale School of Medicine, New Haven, CT
*Purpose: Tacrolimus is widely accepted as the mainstay of immunosuppression in solid organ transplant. Inherited differences in CYP3A activity are known to contribute to dosing…
2020 American Transplant Congress
Recurrence of IgA Nephropathy after Kidney Transplantation – Tango Multicenter Study
A. Uffing¹, P. Cravedi², L. V. Riella¹
¹Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: In patients with IgA nephropathy as the cause of ESKD, IgA deposits can recur in the transplanted kidney. However,the incidence and clinical impact of…
2020 American Transplant Congress
The Impact of Pre-Existing and New Onset Diabetes on Healthcare Utilization Following Kidney Transplantation
D. Taber, N. Pilch, N. Patel, H. Perkins, K. Foster, C. Perez, F. Bartlett, A. Posadas, H. Meadows, K. Soliman, V. Rao, M. Casey, V. Rohan, J. McGillicuddy, S. Nadig, D. Dubay
MUSC, Charleston, SC
*Purpose: Diabetes (DM) represents a global epidemic; it is the leading cause of ESRD in the US and a predominant etiology for kidney transplantation (KTX).…
2020 American Transplant Congress
Impact of Allograft Nephrectomy on Outcomes in Second Kidney Transplantation
N. Sato, Y. Kakuta, T. Kanzawa, K. Unagami, M. Okumi, H. Ishida, K. Tanabe
Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
*Purpose: The impact of failed allograft nephrectomy on the outcome of second kidney transplantation is not clear. We evaluated the effects of the first allograft…
2020 American Transplant Congress
Technology Access, Use, and Intent among Kidney Transplant Candidates Vulnerable to Health Disparities
S. Smith¹, M. Keller², R. Seibert³, L. Kayler¹
¹Transplant, Transplant and Kidney Care Regional Center of Excellence, Erie County Medical Center, Buffalo, NY, ²Transplant, University at Buffalo, State University of New York, Department of Community Health and Health Behavior, Buffalo, NY, ³Transplant, University at Buffalo, State University of New York, Department of Epidemiology and Environmental Health, Buffalo, NY
*Purpose: Advances in eHealth have created opportunities to reach vulnerable populations, however, eHealth strategies could paradoxically increase health disparities if vulnerable individuals lack technology access…
2020 American Transplant Congress
Successful Transplantation of the Kidney Graft with 5 Arteries and Intimal Dissection Injury – 9 Year Follow Up
P. J. Bachul¹, A. Perez-Gutierrez¹, R. Saoud¹, B. Juengel¹, D. J. Grybowski¹, P. Borek¹, R. Anteby², A. Lucander¹, M. Dimitrov¹, J. Fung¹, P. Witkowski¹
¹Surgery, University of Chicago, Chicago, IL, ²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
*Purpose: Utilization of the Carrel patch allows easier implantation of the kidney graft with multiple small renal arteries. If it is not feasible, side-to-side renal…
2020 American Transplant Congress
Outcomes of Post-Transplant Desensitization in High Immunological Risk Deceased Donor Kidney Transplant Recipients
D. Kumar, C. Song, L. Kamal, I. Moinuddin, M. Levy, C. Bhati, A. King, P. Kimball, G. Gupta
Virginia Commonwealth University, Richmond, VA
*Purpose: The kidney allocation system (KAS) was changed in 2015 to increase access to transplants for highly sensitized patients. However, recent data suggests that even…
2020 American Transplant Congress
A Single-Center Experience in Transfusion-Free Liver Transplantation: Referrals and Outcomes from 2005 to 2019
B. H. Horwich¹, A. Mulgaonkar¹, B. Kim², N. Kaur¹, J. Kahn², Y. Genyk³, A. Ahearn³, H. Han²
¹Internal Medicine, University of Southern California, Los Angeles, CA, ²GI & Liver Diseases, University of Southern California, Los Angeles, CA, ³Surgery, University of Southern California, Los Angeles, CA
*Purpose: The Jehovah’s Witnesses is a religious group known to the medical community for its non-acceptance of blood products. This poses a significant challenge in…