ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Association of Kidney Allograft Fibrosis-Associated Proteins with Chronic Lung Allograft Dysfunction

    S. Farkona1, G. Berra2, Z. Mohammed-Ali1, P. Ly2, L. Levy2, B. Renaud-Picard2, G. Zehong2, T. Daigneault2, S. Juvet2, C. McEvoy1, S. Clotet-Freixas1, T. Martinu2, A. Konvalinka1

    1Nephrology, Toronto General Hospital Research Institute and Multi-Organ Transplant, University Health Network, Toronto, ON, Canada, 2Lung Transplantation, Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD) remains the leading cause of long-term mortality after lung transplant. Non invasive biomarkers that could assist in early diagnosis…
  • 2020 American Transplant Congress

    Next Generation Sequencing B Cell Receptor Reveals B Cell Clones Encoding HLA Antibody in Transplant Recipients

    X. Zhang

    HLA and Immunogenetcis Laboratory /CTC, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: The development of HLA donor specific antibodies (DSA) increases the risk of antibody mediated rejection and is an independent predictor of poor patient survival.…
  • 2020 American Transplant Congress

    Improving Evaluation and Follow-Up of Living Kidney Donors: Role of Radioisotopic Glomerular Filtration Rate and Renal Functional Reserve

    V. Cantaluppi1, G. Guglielmetti1, U. M. Morosini1, A. Nappo1, G. Merlotti1, A. Airoldi1, M. Quaglia1, C. Ronco2

    1Nephrology and Kidney Transplantation Unit, University of Piemonte Orientale (UPO), Novara, Italy, 2Nephrology, Dialysis and Kidney Transplantation Unit, University of Padova, Vicenza, Italy

    *Purpose: After donation, living kidney donors (KD) develop an early and transient loss of kidney function (KF), defined as Acute Kidney Injury (AKI). Its recovery…
  • 2020 American Transplant Congress

    MELD is MELD is MELD? Geographic/ Center-Level Variation in Mortality for Patients with the Same MELD Score

    T. Ishaque1, A. B. Massie1, A. B. Kernodle1, S. Getsin1, P. Chaing1, J. G. Jacqueline Garonzik Wang1, S. Gentry2, D. Segev1

    1Johns Hopkins University, Baltimore, MD, 2Department of Mathematics, United States Naval Academy, Annapolis, MD

    *Purpose: Waitlist candidates living in areas with poor access to health care may have higher mortality risk compared to candidates with same MELD in other…
  • 2020 American Transplant Congress

    The Efficacy and Safety of Ischemia-Free Liver Transplantation (IFLT) in the Treatment of End-Stage Liver Disease in a Prospective, Randomized, Controlled Trial: A Report of the First 25 Cases

    X. He, Z. Guo, Q. Zhao, C. Huang, W. Ju, D. Wang, M. Chen, L. Wu, Y. Ma, Y. Chen, A. Hu, X. Zhu

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    *Purpose: We’ve established a novel procedure called ischemia-free liver transplantation (IFLT). The results from the pilot study suggest that IFLT might prevent ischemia-reperfusion injury (IRI)…
  • 2020 American Transplant Congress

    CD11b is a Novel Alternate Receptor for CD154 During Alloimmunity

    M. L. Ford, D. Liu

    Emory University, Atlanta, GA

    *Purpose: For decades, blockade of CD40-CD154 has been shown to be a highly effective means of inhibiting alloreactive T cell responses and inducing long-term graft…
  • 2020 American Transplant Congress

    Eosinophils Maintain Lung Allograft Tolerance by Sequestering CD8+ T Cells in Bronchial Associated Lymphoid Tissue

    Z. Mei1, Y. Guo1, A. Hata1, A. Banerjee1, D. Li1, A. Manafi1, B. Mahgoub1, D. Kreisel2, A. Gelman2, A. S. Krupnick1

    1Department of Surgery, University of Virginia, Charlottesville, VA, 2Department of Surgery, Washington University in St. Louis, St. Louis, MO

    *Purpose: It has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. But the role of eosinophils in long term maintenance…
  • 2020 American Transplant Congress

    Single Dose Rituximab and Anti-Thymocyte Globulin (ATG) Induction in Hypersensitized Kidney Transplant Recipients

    A. X. Wang, U. Wang, S. Busque, C. R. Lenihan

    Stanford University School of Medicine, Stanford, CA

    *Purpose: Hypersensitized kidney transplant recipients (calculated panel reactive antibody (cPRA) ≥98%) may represent a population at high risk of posttransplant immunologic events. While access to…
  • 2020 American Transplant Congress

    Incidence of Antibody Mediated Rejection in Living Kidney Transplant Recipients with Sensitizing History

    Y. Kakuta1, M. Okumi1, T. Kanzawa1, K. Unagami2, H. Ishida2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan, 2Organ Transplant Regulation, Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: A donor-reactive alloimmune memory response can arise from prior exposure to foreign human leukocyte antigen by sensitization history in transplant recipients. Assessing risk levels…
  • 2020 American Transplant Congress

    Deep Learning for Living Donor Surgery: AI Recognition of Surgical Video to Develop Navigation Systems for Laparoscopic Nephrectomy

    M. Nishihara1, K. Iwadoh2, M. Noriyuki1, I. Koyama2, I. Nakajima2, M. Tonsho1

    1Transplant Surgery, International University of Health and Welfare, Mita Hospital, Tokyo, Japan, 2Kidney Surgery, Tokyo Women's Medical University Hospital, Tokyo, Japan

    *Purpose: Laparoscopic surgery for living donors requires high safety, thus establishing of navigation system for surgical operation is urged. The purpose of this study was…
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