Am J Transplant, Volume 20, Suppl 3 Archives - Page 51 of 223 - ATC Abstracts

2020 American Transplant Congress
Late Onset Primary Graft Dysfunction after Lung Transplantation Correlates with Transplant Arteriosclerosis in a Humanized Mouse Model
M. Franz¹, T. Siemeni¹, A. Knöfel¹, W. Sommer¹, M. Avsar¹, F. Ius¹, I. Tudorache¹, C. Kühn¹, C. S. Falk², G. Warnecke¹, A. Haverich¹
¹Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ²IFB-Tx, Hannover Medical School, Hannover, Germany
*Purpose: Primary Graft dysfunction (PGD) is one of the most important causes of early mortality after lung transplantation. We investigated the correlation between the incidence…
2020 American Transplant Congress
Incidence of Fragility Fractures and Changes in Bone Mineral Density in Type 1 Diabetes Recipients of Pancreas Transplant Alone
Y. C. Kudva, S. Batthula, R. Kaur, B. H. Smith, S. R. Rizvi, P. G. Dean, W. K. Kremers, M. D. Stegall, R. A. Wermers
Mayo Clinic, Rochester, MN
*Purpose: Type 1 Diabetes (T1D) is associated with increased fracture risk. Solid organ transplant recipients are at high risk for fracture but limited data are…
2020 American Transplant Congress
Natural Course of Borderline Changes in Kidney Allografts: A MMDx Study
P. Hruba¹, K. S. Madill-Thomsen², M. Mackova², J. Maluskova³, E. Honsova³, J. Slatinska⁴, P. F. Halloran², O. Viklicky⁴
¹Transplant Laboratory, IKEM, Prague, Czech Republic, ²ATAGC, University of Alberta, Edmonton, AB, Canada, ³Department of Pathology, IKEM, Prague, Czech Republic, ⁴Department of Nephrology, IKEM, Prague, Czech Republic
*Purpose: Molecular assessment of kidney allograft biopsies with Banff borderline changes (BL) category has showed only 30% of rejection phenotype in various post-transplant follow-up and…
2020 American Transplant Congress
Mesenchymal Stromal Cell Treatment of Kidneys During Normothermic Machine Perfusion is Safe and Feasible with Effective Traceability after Transplantation
K. Rozenberg¹, S. Lohmann², M. Pool³, M. Eijken⁴, U. Møldrup⁵, B. Møller⁶, J. Sierra-Parraga⁷, M. Hoogduijn⁷, L. Lo Faro¹, C. Moers³, J. Hunter¹, A. Keller², H. Leuvenink³, C. Baan⁷, R. Ploeg¹, B. Jespersen²
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, ³Department of Surgery, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Renal Medicine, Aarhus University, Aarhus, Denmark, ⁵Department of Urology, Aarhus University, Aarhus, Denmark, ⁶Department of Clinical Immunology, Aarhus University, Aarhus, Denmark, ⁷Department of Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Marginal kidneys are increasingly being accepted to decrease waiting time for a transplant. Normothermic machine perfusion (NMP) is a technique that allows delivery of…
2020 American Transplant Congress
Pleural Exosome Mediated Donor Antigen Trafficking Into Mediastinal Lymph Nodes Represents a Novel Pathway of Recipient T Cell Activation in Lung Transplantation
A. Habertheuer¹, A. Japp², C. Ram³, S. Chatterjee⁴, S. Rostami², L. Korutla⁵, T. Ochiya⁶, A. Naji², D. Kreisel⁷, P. Vallabhajosyula⁵
¹Surgery, University of Pittsburgh, Pittsburgh, PA, ²Surgery, University of Pennsylvania, Philadelphia, PA, ³New York University, New York, NY, ⁴Pathology, University of Pennsylvania, Philadelphia, PA, ⁵Surgery, Yale University, New Haven, CT, ⁶National Cancer Center Japan, Tokyo, Japan, ⁷Surgery, Washington University, St. Louis, MO
*Purpose: Studies in lung transplant models suggest that reestablishment of lymphatic continuum of pulmonary allograft via lymphangiogenesis is required for selective trafficking of donor antigen…
2020 American Transplant Congress
Post-Transplantation Lymph Node Fibrosis: Significant Implications in Transplant Tolerance
X. Li¹, J. Zhao¹, L. Jiang¹, M. Uehara¹, V. Kasinath¹, S. Shin¹, S. G. Tullius¹, J. S. Bromberg², R. Abdi¹
¹Brigham and Women's Hospital, Boston, MA, ²University of Maryland School of Medicine, Boston, MA
*Purpose: Lymph nodes (LNs) have been regarded as primary activation sites for alloimmunity following transplantation, but our group has revealed an additional dimension to their…
2020 American Transplant Congress
Basiliximab Induction in the Obese: One Size Does Fit All
A. D. Reticker¹, D. Choi¹, A. B. Lichvar¹, C. Kane², I. Tzvetanov³, E. Benedetti³, J. J. Benken¹
¹Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL, ²Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ³Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL
*Purpose: Surgical advancements allow more obese (BMI> 30 kg/m2) patients to receive a renal transplant. The original clinical and pharmacokinetic (PK) trials in transplantation immunosuppression…
2020 American Transplant Congress
Does Donor Terminal, Admission or Best Estimate Glomerular Filtration Rate Predicts Kidney Transplantation Outcomes
G. Irish¹, T. Coates², P. Clayton²
¹Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, ²Central and Northern Adelaide Renal and Transplantation Services, Royal Adelaide Hospital, Adelaide, Australia
*Purpose: When assessing deceased kidney donors, a key factor is donor kidney function. It is unclear whether terminal, admission, or the best of terminal and…
2020 American Transplant Congress
The Impact of Increased Visceral Fat in Kidney Transplant Recipients
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: An increased amount of visceral fat (VF) has been reported as a precursor to metabolic syndrome and is a risk factor for renal dysfunction.…
2020 American Transplant Congress
Antimicrobial Prophylaxis Post Antibody Mediated Rejection Treatment in Pediatric Kidney Transplant Recipients: Interim Report from the Paramour “PediAtric Renal AMr Outcomes” Study
S. Solomon¹, R. Garro², N. Hayde³, A. Jain⁴, M. Kallash⁵, K. Twombley⁶, I. Ashoor⁷
¹Maria Fareri Children's Hospital, Valhalla, NY, ²Emory University, Atlanta, GA, ³The Children's Hospital at Montefiore, Bronx, NY, ⁴Children's Hospital of Michigan, Detroit, MI, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶Medical University of South Carolina, Charleston, SC, ⁷LSU Health New Orleans, New Orleans, LA
*Purpose: Universal guidelines do not exist for post antibody mediated rejection (AMR) treatment antimicrobial prophylaxis (ppx) in pediatric kidney transplant (KT) recipients. We sought to…