Am J Transplant, Volume 20, Suppl 3 Archives - Page 46 of 223 - ATC Abstracts

2020 American Transplant Congress
Predictive Validity of Functional Status on Mortality in Adult Kidney Transplant Recipients
N. Chu, Z. Shi, D. Segev, M. McAdams Demarco
Johns Hopkins, Baltimore, MD
*Purpose: Frailty and disabilities, though not routinely measured, are highly prevalent in kidney transplant (KT) recipients and predict poor post-transplant outcomes. The Karnofsky Performance Scale…
2020 American Transplant Congress
Improving Value Delivery in Living Donor Kidney Transplant Through Process Improvement
S. Anand, J. Browning, W. Stapley, M. Egbert, J. Krong, J. Zobell, A. Herbert, S. Dow, L. Dong, D. Morris, T. Srinivas
Intermountain Medical Center, Murray, UT
*Purpose: To increase living donation through process improvement.*Methods: Quality improvement project, with intention to substantially improve the living donor (LD) transplant (Tx) rate. Participants: All…
2020 American Transplant Congress
Pediatric National Liver Review Board: Impact on Children on the Waitlist
J. Foutz¹, S. Noreen¹, E. Hsu², E. Perito³, G. Mazariegos⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF Benioff Children's Hospital, San Francisco, CA, ⁴Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
*Purpose: On 5/14/19 changes were made to the exceptions review process for pediatric liver transplant candidates, with transition from 11 Regional Review Boards to one…
2020 American Transplant Congress
Pre-Transplant Bariatric Surgery is Associated with Increased Fungal Infection after Liver Transplant
M. Jorgenson¹, A. Gracon², B. Hanlon², G. Leverson², D. Al-Adra¹
¹UWHC, Madison, WI, ²UWMF, Madison, WI
*Purpose: The impact of pre-transplant (pre-TXP) bariatric surgery (BS) on outcomes after liver transplant (LTX) has not been completely elucidated. Roux-en Y gastric bypass (RYGB)…
2020 American Transplant Congress
T Follicular Regulatory Cell Deficiency Enhances Secondary T Follicular Helper Cell Responses after Transplantation
E. S. Crichton, S. Zeng, I. Badell
Emory University, Atlanta, GA
*Purpose: Deleterious alloantibodies result from T follicular helper (Tfh) cell-driven germinal center (GC) reactivity. T follicular regulatory (Tfr) cells are a subset of regulatory T…
2020 American Transplant Congress
IL-6 Receptor Blockade But Not IL-2 Treatment Contributes to Long-Term NHP Cardiac Allograft Survival in Transient Mixed Chimeras
K. Ahrens¹, J. M. O¹, W. Sommer², J. Morrissette¹, D. Becerra¹, P. M. Patel¹, T. Costa¹, A. Dehnadi¹, I. M. Hanekamp¹, J. S. Allan³, G. Benichou¹, J. C. Madsen⁴
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ³Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, ⁴Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Long-term tolerance of cardiac allografts has been achieved in non-human primates (NHPs) using a mixed chimerism protocol and by co-transplanting a kidney from the…
2020 American Transplant Congress
Safety Outcomes in Lower-Weight vs Higher-Weight Recipients of Fixed Dose Alemtuzumab for Kidney Transplant Induction
A. Freeman, S. Anders, B. Wise, M. Janusek, L. Hutchinson, U. Kaszubski, D. Marroquin, D. Martin, H. Bohorquez
Ochsner Medical Center, New Orleans, LA
*Purpose: Alemtuzumab is a lymphocyte-depleting monoclonal antibody used for renal transplant induction, and is associated with significant leukopenia, increased infections and malignancy. Multiple dosing strategies…
2020 American Transplant Congress
Antibody-Mediated Rejection with and without Donor-Specific Anti-HLA Antibodies: Performance of the Peripheral Blood 8-Gene Expression Assay
E. Van Loon¹, E. Lerut², D. Anglicheau³, W. Gwinner⁴, M. Essig⁵, P. Marquet⁵, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²KU Leuven, Leuven, Belgium, ³Department of Nephrology and Kidney Transplantation, Necker Hospital, Paris, France, ⁴Hannover Medical School, Hannover, Germany, ⁵CHU Limoges, Limoges, France
*Purpose: Therapeutic implications of the recently discovered 8-gene expression assay are most clear for detection of antibody-mediated rejection in presence of donor-specific anti-HLA antibodies (HLA-DSA).…
2020 American Transplant Congress
The Effect of Intravenous Acetaminophen on Opioid Use in Laparoscopic Donor Nephrectomy Patients
C. Makosiej, A. Eisenhart
Saint Barnabas Medical Center, Livingston, NJ
*Purpose: The purpose of this study was to determine if intravenous acetaminophen (IV APAP) use affects the daily and cumulative opioid requirements of patients undergoing…
2020 American Transplant Congress
Geographic Variation in Characteristics of High-KDPI Donors
G. R. Vece¹, A. Wilk¹, N. Turgeon²
¹United Network for Organ Sharing, Richmond, VA, ²Dell Seton Medical Center, Austin, TX
*Purpose: The kidney donor profile index (KDPI) was incorporated into kidney allocation in the United States in 2014, and discard rates for high-KDPI donors (86-100%)…