ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Racial Differences in Acceptance of Public Health Service (PHS) Increased Risk Kidneys and Hepatitis C (HCV) Nat Positive Kidneys

    K. Atiemo, S. Giusti, A. Paramesh, M. Killackey, H. Jeon

    Tulane University, New Orleans, LA

    *Purpose: PHS increased risk kidneys and HCV NAT positive kidneys represent a significant proportion of the donor pool however, acceptance demands explicit patient consent that…
  • 2020 American Transplant Congress

    Variability in Educational Content about Kidney Paired Donation at 68 National Kidney Registry-Affiliated Centers

    A. D. Waterman1, O. N. Ranasinghe1, E. H. Wood1, J. L. Beaumont2, S. McGuire3, K. Miller4, V. Chipman5, J. Sinacore6, M. Cooper7

    1Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, 2Terasaki Research Institute, Los Angeles, CA, 3UCLA Kidney and Pancreas Transplant Programs, Los Angeles, CA, 4UW Health, Madison, WI, 5UCSF Medical Center, San Francisco, CA, 6National Kidney Registry, Babylon, NY, 7Medstar Georgetown Transplant Institute, Washington, DC

    *Purpose: Equipping patients and donors with in-depth information about kidney paired donation (KPD) processes, risks, benefits, and protections is necessary for informed decision-making and comfort.…
  • 2020 American Transplant Congress

    Introducing the Smartphone App, EL-FIT (Exercise & Liver FITness), to Help Monitor and Prehabilitate Liver Transplant Candidates

    A. Duarte-Rojo1, P. M. Bloomer1, R. J. Rogers2, M. A. Dunn1, E. B. Tapper3, R. Bataller1, C. B. Hughes1, A. A. Ferrando1, W. R. Kim4, J. M. Jakicic2

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Michigan, Ann Arbor, MI, 4Stanford University, Palo Alto, CA

    *Purpose: Physical activity is key to liver transplant (LT) prehabilitation, and leveraging technologies to monitor physical performance and to generalize training may be advantageous. EL-FIT…
  • 2020 American Transplant Congress

    Effectiveness of Bezlotoxumab for Prevention of Recurrent Clostridioides Difficile Infection among Transplant Recipients

    V. Bajrovic1, T. Johnson2, A. Howard2, L. Allen3, G. Barber2, K. Schwarz2, M. Huang3, M. Abidi1, E. Benamu3, P. Ramanan3, M. Miller4

    1Division of Infectious Diseases, University of Colorado, Denver, CO, 2Department of Pharmacy, University of Colorado, Aurora, CO, 3Division of Infectious Diseases, University of Colorado, Aurora, CO, 4Department of Pharmacy, University of Colorado, Denver, CO

    *Purpose: Clostridioides difficile is an urgent health threat associated with significant morbidity and mortality. Recipients of solid organ (SOT) and hematopoietic-cell transplantations (HCT) are at…
  • 2020 American Transplant Congress

    Divergent Molecular Pathways Underlie the Evolution of Allograft Fibrosis in Two Mouse Models of Chronic Lung Allograft Dysfunction

    T. Watanabe, J. Allen, K. Boonstra, Z. Guan, K. Bei, S. Keshavjee, J. Yeung, T. Martinu, S. Juvet

    Latner Thoracic Surgery Research Laboratories, Toronto Lung Transplant Program / University Health Network, Toronto, ON, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD) after lung transplantation (LTx) is potentiated by activation of the innate immune system and occurs in two patterns: diffuse…
  • 2020 American Transplant Congress

    Overcoming Ab-Mediated Xenolung Rejection: Beta4Gal is an Important Pre- and Post-Transplant Ab Target, Relevant to Xenograft Injury in Baboons

    L. Burdorf1, Z. Abady1, B. Cerel1, K. Petitpas1, C. Laird2, S. Pratts1, X. Cheng2, C. J. Phelps3, W. Eyestone3, D. L. Ayares3, R. N. Pierson III1, A. M. Azimzadeh1

    1Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Surgery, University of Maryland, Baltimore, MD, 3Revivicor, Blacksburg, VA

    *Purpose: Knock-out (KO) of porcine carbohydrates (CHO), including Gal 1,3αGal, inhibits antibody-mediated xenograft rejection. The β4Gal epitope was discovered using serum from xenograft-sensitized baboons, but…
  • 2020 American Transplant Congress

    Belatacept-Based, Calcineurin Inhibitor and Corticosteroid Free Immunosuppression: Differential Outcomes Based on Recipient Age

    N. Wilson1, A. R. Shields2, D. Kaufman3, A. Wiseman4, A. L. Christianson1, S. Tremblay1, J. P. Leone5, A. J. Matas6, P. West-Thielke7, R. R. Alloway1, E. S. Woodle1

    1U Cincinnati, Cincinnati, OH, 2The Christ Hospital, Cincinnati, OH, 3U Wisconsin, Madison, WI, 4U Colorado, Denver, CO, 5Tampa General, Tampa, FL, 6U Minnesota, Minneapolis, MN, 7U Illinois Chicago, Chicago, IL

    *Purpose: Age-based disparities have been described in calcineurin inhibitor (CNI)-based immunosuppression regimens, but are not well-described for belatacept (BELA)-based regimens. This study analyzed the effect…
  • 2020 American Transplant Congress

    Timing of Bariatric Surgery for Obese Kidney Transplant Candidates

    R. A. Choudhury1, D. Yoeli1, G. Hoeltzel2, H. B. Moore1, H. Yaffe1, K. R. Dumon3, N. N. Williams3, P. L. Abt4, K. D. Conzen1, T. Pshak1, P. T. Kennealey1, T. L. Nydam1

    1Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, 2Thomas Jefferson University Hospital, Philadelphia, PA, 3Department of Surgery, University of Pennsylvania Hospital, Philadelphia, PA, 4Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA

    *Purpose: The high risk profile of bariatric surgery in obese end-stage-renal disease (ESRD) patients has caused many to suggest that surgery should be reserved for…
  • 2020 American Transplant Congress

    Effects of Mandatory 6-Month Waiting Time Policy on Post-Transplant Outcomes and Explant Pathology in Liver Transplant Patients with Hepatocellular Carcinoma

    S. Nagai, T. Kitajima, S. Yeddula, R. Salgia, M. Abouljoud, D. Moonka

    Henry Ford Hospital, Detroit, MI

    *Purpose: In the United States, current allocation policy mandates a 6-month waiting period before exception scores are granted to liver transplant (LT) candidates with hepatocellular…
  • 2020 American Transplant Congress

    American Muslims & Informed Organ Donation Decisions: Findings from a Randomized, Controlled Trial of Religiously-Tailored Education in Mosques

    A. I. Padela1, R. Duivenbode2, M. Quinn1, M. Craig3, M. Saunders1

    1Department of Medicine, The University of Chicago, Chicago, IL, 2Initiative on Islam and Medicine, The University of Chicago, Chicago, IL, 3The National Kidney Foundation Illinois, Chicago, IL

    *Purpose: American Muslims hold more negative attitudes towards organ donation than other American populations, and these attitudes are associated with gaps in biomedical and religious…
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