Am J Transplant, Volume 20, Suppl 3 Archives - Page 43 of 223 - ATC Abstracts

2020 American Transplant Congress
Artificial Intelligence May Detect Donor Liver Steatosis and Predict Early Post-Transplantation Graft Failure
R. R. Narayan, L. Yang, N. Abadilla, S. B. Chen, J. P. Higgins, M. L. Melcher
Stanford University, Stanford, CA
*Purpose: To compare the accuracy of donor liver biopsy slides scored by manual histopathologic review versus a computer vision artificial intelligence (CVAI) platform to predict…
2020 American Transplant Congress
Pre-Transplant Monocyte HDAC6 Expression and Risk of Primary Graft Dysfunction in Clinical Lung Transplant Recipients
T. Akimova¹, T. Zhang¹, L. Wang¹, J. D. Christie², W. W. Hancock¹
¹Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA
*Purpose: Lung transplantation (Tx) in ~30% of cases is subject to primary graft dysfunction (PGD), the severe acute lung injury that occurs within 72 hours…
2020 American Transplant Congress
In-Vivo Application of Ides (Imlifidase) in Nonhuman Primates Results in Xenoreactive Desensitization: A Novel Anti-Humoral Therapy
B. P. Lovasik¹, A. J. Matar¹, D. A. Faber¹, D. V. Mathews¹, C. Breeden¹, S. C. Kim¹, A. J. Tector², A. Robertson³, C. Kjellman³, A. B. Adams¹
¹Emory University School of Medicine, Atlanta, GA, ²University of Miami, Miami, FL, ³HANSA Biopharma, Lund, Sweden
*Purpose: Antibody-mediated rejection is a formidable barrier to xenograft survival. A novel anti-humoral IdeS therapy, which cleaves serum IgG, represents a promising therapy to reduce…
2020 American Transplant Congress
Predicting Kidney Allograft Discard: The Kidney Discard Risk Index
M. B. Price, M. Joshi, T. Zhang, J. Vierling, T. Galvan, R. Cotton, C. O'Mahony, J. Goss, A. Rana
Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: The disparity between the supply and demand for kidney allografts is exacerbated by an 18.9% discard rate. It is our aim to determine predictors…
2020 American Transplant Congress
HIV+ Living Kidney Donors in the United States: Cases and a Clinical Paradigm
D. Segev¹, C. Wolfe², D. Brown³, D. Fine³, K. Neumann⁴, N. Martinez⁵, D. Ostrander³, F. Al Ammary³, A. Tobian³, A. W. Baker⁶, C. Durand³
¹Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD, ²Duke University Medical Center, Durham, NC, ³Johns Hopkins University, School of Medicine, Baltimore, MD, ⁴Unaffiliated, N/A, VA, ⁵Unaffiliated, N/A, GA, ⁶Duke University, School of Medicine, Durham, NC
*Purpose: To report clinical characteristics and outcomes of two people living with HIV who underwent laparoscopic donor nephrectomy*Methods: To facilitate donor selection, we first conducted…
2020 American Transplant Congress
Younger Age is Associated with Improved Survival in Patients Undergoing Liver Transplantation Alone for Metastatic Neuroendocrine Tumors
R. Gedaly, D. Valvi, X. Mei, M. Gupta, M. Shah, A. Ancheta, F. Marti
University of Kentucky, Lexington, KY
*Purpose: Neuroendocrine tumor (NET) metastases are a major cause of morbidity and mortality. The role of liver transplantation to treat unresectable metastases from NET is…
2020 American Transplant Congress
Donor-Derived Gram-Negative Infections in Solid Organ Transplant Recipients: OPTN DTAC Experience, 2012-2018
S. Pouch¹, B. Plucinski², R. La Hoz¹, A. Agarwal¹, S. Aslam¹, L. Danziger-Isakov¹, S. Ho¹, D. Levine¹, M. Malinis¹, M. Rana¹, R. Razonable¹, L. Strasfeld¹, M. Michaels¹
¹OPTN DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: Rates of Gram-negative (GN) organ donor disease transmission are unknown. Potential donor-derived transmission events (PDDTE) reported to the OPTN Ad hoc Disease Transmission Advisory…
2020 American Transplant Congress
Impact of Pretransplant Malignancy on Heart and Lung Transplant Recipients
W. Kang¹, C. T. Sparrow², M. Kim¹, M. Rachid³, S. M. Soriano³
¹Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, ²Department of Cardiology, University of Illinois College of Medicine at Peoria, Peoria, IL, ³Department of Pulmonology, University of Illinois College of Medicine at Peoria, Peoria, IL
*Purpose: The purpose of this study is to investigate pre-transplant malignancy (PTM) as a risk factor for worsened post-transplant prognosis in heart or lung transplant…
2020 American Transplant Congress
Factors Associated with Renal Graft Loss in Simultaneous Kidney-Heart Transplant Recipients in the UNOS Cohort
K. A. Agarwal¹, H. Patel¹, K. Almonte², F. Cardarelli¹, N. Agrawal¹
¹Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Medicine, Mount Auburn Hospital, Cambridge, MA
*Purpose: Simultaneous kidney and heart transplants (SKHT) are employed for patients with both end-stage heart failure and severely impaired kidney function. Renal outcomes in such…
2020 American Transplant Congress
High Frequencies of Donor-Derived Memory T and NK Cells in the Blood of Lung Transplant Recipients May Contribute to Protection from Chronic Lung Allograft Dysfunction
R. Bellmàs Sanz¹, A. Hitz¹, B. Wiegmann², K. Bläsing¹, F. Ius², W. Sommer², J. Kühne¹, L. Horn¹, A. Knöfel², I. Tudorache², A. Haverich², D. Jonigk³, G. Warnecke², C. Falk¹
¹Institute of Transplant Immunology, Hannover Medical School MHH, Hannover, Germany, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School MHH, Hannover, Germany, ³Institute of Pathology, Hannover Medical School MHH, Hannover, Germany
*Purpose: After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the…