Am J Transplant, Volume 20, Suppl 3 Archives - Page 42 of 223 - ATC Abstracts

2020 American Transplant Congress
A Large Animal Model of Ex-Vivo Lung Perfusion as a Platform to Deliver Therapeutic Agents to Lungs Before Lung Transplant
T. M. Egan¹, B. Haithcock¹, M. H. Ali¹, J. W. Blackwell¹, B. Masuodi¹, S. Shipley², T. Long³, A. Akerman¹, S. Montgomery⁴, H. Yuan⁵, P. Stewart⁶, J. Potenziano⁷, C. Sekaran⁷, R. Fitch⁷
¹Surgery, UNC at Chapel Hill, Chapel Hill, NC, ²Department of Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ³Pathology and Laboratory Medicine,, UNC at Chapel Hill, Chapel Hill, NC, ⁴Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ⁵Radiology, UNC at Chapel Hill, Chapel Hill, NC, ⁶Gillings Global School of Public Health, UNC at Chapel Hill, Chapel Hill, NC, ⁷Mallinckrodt Pharmaceuticals, Hazelwood, MO
*Purpose: Ex-vivo lung perfusion (EVLP) has been used to evaluate lung function before lung transplant (LT). We used EVLP to expose lungs recovered 6 hours…
2020 American Transplant Congress
Clinical and Demographic Factors Affecting Patient and Graft Survival in Pancreas Transplant Recipients: The Efispan Study
P. Ventura-Aguiar¹, M. Cabello², I. Beneyto³, D. Navarro Cabello⁴, G. Tabernero⁵, A. Alonso⁶, J. Ruiz⁷, S. Llorente⁸
¹Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain, ²Department of Nephrology, Hospital Carlos Haya, Malaga, Spain, ³Department of Nephrology, Hospital La Fe, Valencia, Spain, ⁴Department of Nephrology, Hospital Reina Sofía, Cordoba, Spain, ⁵Department of Nephrology, Hospital Universitario de Salamanca, Salamanca, Spain, ⁶Department of Nephrology, Hospital Universitario de A Coruña, A Coruña, Spain, ⁷Department of Nephrology, Hospital Marqués de Valdecilla, Santander, Spain, ⁸Department of Nephrology, Hospital Virgen de la Arrixaca, Murcia, Spain
*Purpose: Pancreas transplantation is an established treatment for diabetic patients with end-stage renal disease. Graft outcomes have improved in the last decades, but data regarding…
2020 American Transplant Congress
Long Term Liver Transplant Survivors
M. Haberal¹, E. Ayvazoglu Soy¹, G. Moray¹, F. Ozcay², A. Torgay³
¹Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey, ²Pediatric Nephrology, Baskent University, Ankara, Turkey, ³Anaesthesia, Baskent University, Ankara, Turkey
*Purpose: Few reports mentioned about long term survey. In this study, we aimed to report the outcomes of our long term LT survivors (LTS).*Methods: Our…
2020 American Transplant Congress
Cyclophilin-D Inhibition Mitigates Cardiac Allograft Ischemia-Reperfusion Injury and Rejection
A. Qamar¹, P. McLeod², J. Jiang², X. Huang², A. M. Jevnikar², Z. Zhang²
¹Pathology & Laboratory Medicine, University of Western Ontario, London, ON, Canada, ²London Health Sciences Center, London, ON, Canada
*Purpose: The clinical relevance of ischemia-reperfusion injury (IRI) in the context of organ transplantation is well-established. IRI is associated with various forms of programmed cell…
2020 American Transplant Congress
Contamination of Acinar Cells Impairs Therapeutic Effect of Islet Transplantation Due to Induction of Inflammatory Reaction in Not Only Graft Islets but Also Hepatic Parenchyma
K. Chinen, G. Yoshimatsu, N. Sakata, S. Kodama
Regenerative Medicine and Transplantation, Fukuoka University, Fukuoka City, Japan
*Purpose: Islet transplantation is a promising treatment option for type 1 diabetes. Edmonton protocol recommended that over 30 % purity of islets is essential for…
2020 American Transplant Congress
Intra-Lymph Node Injection of Microparticles Reprograms the Laminin Stromal Network to Prolong Allograft Survival
C. M. Paluskievicz¹, Y. Xiong¹, W. Piao¹, M. Willson-Shirkey¹, H. Eppler², C. M. Jewell², J. S. Bromberg¹
¹U Maryland, Baltimore, MD, Baltimore, MD, ²U Maryland, College Park, MD, College Park, MD
*Purpose: Microparticles (MPs) carrying peptide antigen with immune signals can be directly delivered to lymph nodes (LNs) to induce pro-inflammatory or anti-inflammatory responses. We hypothesized…
2020 American Transplant Congress
Safety and Efficacy of Low Dose Rabbit Antithymocyte Globulin in Pediatric Renal Transplant Recipients
V. K. Sigurjonsdottir¹, L. Maestretti¹, A. McGrath¹, A. Gallo², W. Concepcion², P. Grimm¹, A. Chaudhuri¹
¹Pediatric Nephrology, Stanford University, Stanford, CA, ²Surgery - Multi-Organ Transplantation, Stanford University, Stanford, CA
*Purpose: Currently there is no consensus among pediatric kidney transplant centers regarding the use and regimen for immunosuppressive induction therapy.The safety and effectiveness of reduced…
2020 American Transplant Congress
Does Donor Terminal, Admission or Best Estimate Glomerular Filtration Rate Predicts Kidney Transplantation Outcomes
G. Irish¹, T. Coates², P. Clayton²
¹Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, ²Central and Northern Adelaide Renal and Transplantation Services, Royal Adelaide Hospital, Adelaide, Australia
*Purpose: When assessing deceased kidney donors, a key factor is donor kidney function. It is unclear whether terminal, admission, or the best of terminal and…
2020 American Transplant Congress
The Impact of Increased Visceral Fat in Kidney Transplant Recipients
Y. Miyauchi, T. Noda, N. Miura, T. Kikugawa, T. Saika
Ehime University, Toon, Japan
*Purpose: An increased amount of visceral fat (VF) has been reported as a precursor to metabolic syndrome and is a risk factor for renal dysfunction.…
2020 American Transplant Congress
Antimicrobial Prophylaxis Post Antibody Mediated Rejection Treatment in Pediatric Kidney Transplant Recipients: Interim Report from the Paramour “PediAtric Renal AMr Outcomes” Study
S. Solomon¹, R. Garro², N. Hayde³, A. Jain⁴, M. Kallash⁵, K. Twombley⁶, I. Ashoor⁷
¹Maria Fareri Children's Hospital, Valhalla, NY, ²Emory University, Atlanta, GA, ³The Children's Hospital at Montefiore, Bronx, NY, ⁴Children's Hospital of Michigan, Detroit, MI, ⁵Nationwide Children's Hospital, Columbus, OH, ⁶Medical University of South Carolina, Charleston, SC, ⁷LSU Health New Orleans, New Orleans, LA
*Purpose: Universal guidelines do not exist for post antibody mediated rejection (AMR) treatment antimicrobial prophylaxis (ppx) in pediatric kidney transplant (KT) recipients. We sought to…