Am J Transplant, Volume 20, Suppl 3 Archives - Page 42 of 223 - ATC Abstracts

2020 American Transplant Congress
An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion/Injury in a Murine Model
A. Kobayashi¹, A. Wanchoo², J. Simonovich², S. Duarte¹, V. Boominathan¹, S. Shrestha¹, G. Hudalla², B. Keselowsky²
¹Surgery, University of Florida, Gainesville, FL, ²Biomedical Engineering, University of Florida, Gainesville, FL
*Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor organs. However, despite its obvious…
2020 American Transplant Congress
The Pleural Cavity, A Novel and Clinically Relevant Site for Pancreatic Islet Transplantation
Q. Yuan¹, K. Lee¹, C. Rickert¹, S. Hong¹, E. Acheampong¹, E. Szuter¹, Y. Xu², K. Deng¹, N. Feeney¹, Q. Fu¹, G. Huai¹, J. Lei¹, I. Rosales¹, P. Russell¹, J. Madsen¹, R. Colvin¹, A. Alessandrini¹, J. Markmann¹, -. Q.Y. and K.L.³, -. A.A. and J.F.M.⁴
¹Massachusetts General Hospital, Boston, MA, ²Chinese PLA General Hospital & Medical School, Beijing, China, ³Co-First Authors, Boston, MA, ⁴Co-Senior Authors, Boston, MA
*Purpose: Islet transplantation currently provides a cure for type 1 diabetes. Hepatic infusion of islets via the portal vein is clinically accepted in human, although…
2020 American Transplant Congress
Unique Podocyte and Multiplex Single-Cell RNASeq Analysis of Paired Sera and Bone Marrow Samples Suggest a Role for Perturbed Hematopoeitic Progenitors in FSGS Recurrence
P. Rashmi, T. Sigdel, A. Alica Da Silva, R. Paul, D. Galligan, J. Wolfe, F. Vincenti, M. Sarwal
University of California San Francisco, San Francisco, CA
*Purpose: Focal Segmental Glomerulosclerosis (FSGS) is the most common cause of nephrotic syndrome, can lead to ESRD, and carries a high burden of recurrence risk…
2020 American Transplant Congress
Prevalence of Risk Factors for NAFLD among Living Liver Donors
D. A. Axelrod¹, M. Simpson², E. Pomfret³, A. Ehrlich⁴, S. Rwema⁴, R. Chung⁴, F. Gordon⁵
¹Surgery, University of Iowa, Iowa CIty, IA, ²Surgery, Lahey Clinic, Burlington, MA, ³University of Colorado, Denver, CA, ⁴Mass General Hospital, Boston, MA, ⁵Lahey, Burlington, MA
*Purpose: The development of non-alcoholic fatty liver (NAFLD) disease has been strongly associated with the presence of polymorphisms in PNPLA3 rs738409. When compared with wild…
2020 American Transplant Congress
Renal Transplant Induction Therapy Safety Outcomes Comparison
R. M. Hofmann¹, J. Combs², K. J. Schmidt³, T. Dyckman⁴
¹Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, ²Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, ³Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, ⁴Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI
*Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
2020 American Transplant Congress
Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients
A. Brar¹, A. Gruessner², D. Adey¹, M. Salifu²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…
2020 American Transplant Congress
Safety and Efficacy of Direct-Acting Oral Anticoagulants versus Warfarin in Kidney Transplant Recipients
A. L. Bixby¹, S. A. Shaikh², A. S. Naik³, L. Cotiguala³, K. McMurry³, M. D. Samaniego-Picota⁴, V. D. Marshall⁵, J. M. Park³
¹University Hospitals Cleveland Medical Center, Cleveland, OH, ²Keck Medical Center of USC, University of Southern California, Los Angeles, CA, ³Michigan Medicine, Ann Arbor, MI, ⁴Henry Ford Transplant Institute, Detroit, MI, ⁵University of Michigan College of Pharmacy, Ann Arbor, MI
*Purpose: Safety and efficacy of direct-acting oral anticoagulants (DOACs) have not been well studied in solid organ transplant. The purpose of our study was to…
2020 American Transplant Congress
Living Kidney Donor Assessment: Kidney Length versus Differential Function
K. J. Schumacher, J. A. Akoh
General and Transplant Surgery, Plymouth University Hospitals NHS Trust, Plymouth, United Kingdom
*Purpose: The key question in living kidney donor assessment is how best to determine the contribution of each kidney to overall renal function as a…
2020 American Transplant Congress
The Long Term Impact of Metabolic Syndrome on Post-Donation in Living Kidney Donors
C. Chen, T. Yu, Y. Chuang, S. Tsai, M. Wu
Division of Nephrology, Taichung Veterans General Hospital, Taichung, Taiwan
*Purpose: The long waiting list for kidney transplant (KTx) in Taiwan, the willingness of transplant centers increase to accept complex donors, eg. metabolic syndrome (MS).…
2020 American Transplant Congress
Validation of Patient Reported Outcomes Measurement Information System (PROMIS) Computer Adaptive Testing Depression Item Bank in Kidney Transplant Recipients
V. Shah¹, A. Rezaeishahreza¹, E. Lui¹, R. Aser¹, S. Bartlett², M. Li¹, D. Howell¹, J. Peipert³, M. Novak¹, I. Mucsi¹
¹University Health Network, Toronto, ON, Canada, ²McGill University, Montreal, QC, Canada, ³Northwestern University, Chicago, IL
*Purpose: To evaluate the reliability and validity of the PROMIS Depression computerized adaptive test (PROMIS-D CAT) in relation to a legacy measure in adult Kidney…