Am J Transplant, Volume 20, Suppl 3 Archives - Page 4 of 223 - ATC Abstracts

2020 American Transplant Congress
Comparative Analysis of Risks Factors for Kidney Allograft Loss Due to Bk Nephropathy and Graft Loss Due to Other Causes: UNOS Data Set
H. Patel¹, L. Kruger¹, K. Agarwal¹, A. Pawar¹, N. Leeaphorn², F. Cardarelli¹, N. Agrawal¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO
*Purpose: 1-10% of the kidney transplant recipients develop BK virus nephropathy (BKVN). The risk factors associated with BKVN are not clearly understood. Here, we evaluate…
2020 American Transplant Congress
CCL18 Plays a Crucial Role in T Cell Recruitment in Upper Extremity Transplant Rejection
T. J. Borges¹, P. Abarzua², B. Kollar², M. Lima-Filho¹, B. T. Aoyama¹, G. F. Murphy², B. Pomahac², C. G. Lian², S. G. Talbot², L. V. Riella¹
¹Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA
*Purpose: Upper extremity transplantation (UET) is a life-changing procedure for amputee patients. However, 90% of patients experience acute skin rejection in the first post-transplant year,…
2020 American Transplant Congress
Pilot Study: Effect of Dual Ex Vivo Lung Perfusion on Human Lung Preservation
K. Noda¹, J. Sembrat², B. J. Philips¹, T. Harano¹, M. Rojas², P. G. Sanchez¹, N. Shigemura³
¹Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, ²Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, ³Division of Cardiovascular Surgery, Temple University, Philadelphia, PA
*Purpose: We have developed a novel lung preservation technique, dual ex vivo lung perfusion (dual EVLP) where both pulmonary artery (PA) and bronchial artery (BA)…
2020 American Transplant Congress
Prolonged In Vivo Perfusion of a Re-Endothelialized Human-Scale Tissue Engineered Kidney Graft
J. S. Uzarski¹, E. E. Russell¹, E. C. Beck¹, M. Holzner², V. Wadhera², D. Adamson², T. Gilbert¹, S. Florman², D. S. Davidow¹, R. Shapiro², J. Ross¹
¹Research & Development, Miromatrix Medical Inc., Eden Prairie, MN, ²Recanati/Miller Institute, Mount Sinai, New York, NY
*Purpose: Advances are desperately needed to increase the supply of transplantable kidneys for the 100,000 patients on the waiting list. Whole organ engineering is one…
2020 American Transplant Congress
Simultaneous Robotic Kidney Transplantation and Sleeve Gastrectomy versus Transplant Alone for Morbidly Obese Patients with End-Stage Renal Failure: A Prospective Randomized Trial
K. A. Tulla, P. West-Thielke, P. DiCocco, O. Okoye, K. Bruno, J. Almario Alvarez, M. Spaggiari, I. G. Tzvetanov, E. Benedetti
University of Illinois at Chicago, Chicago, IL
*Purpose: The purpose of this study is to demonstrate that simultaneous robotic assisted kidney transplant and robotic assisted sleeve gastrectomy results in fewer surgical complications…
2020 American Transplant Congress
Carfilzomib-Based Desensitization: Effects on HLA, Non-HLA, Auto, and Antiviral Antibodies
S. Tremblay¹, E. Portwood¹, A. R. Shields², R. R. Alloway¹, P. A. Brailey¹, E. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²U Cincinnati, Christ Hospital, Cincinnati, OH
*Purpose: An important question in plasma cell (PC) therapies is the specificity of therapy for PC populations. It is known that plasmablast populations are exquisitely…
2020 American Transplant Congress
Long-Term Metabolic Control and Health Outcomes in Maple Syrup Urine Disease Following Liver Transplantation in Children and Young Adults
C. Ewing¹, K. Soltys², K. Strauss³, G. Mazariegos², R. Sindhi², J. Vockley², P. McKiernan², R. Squires², G. Bond², A. Khanna², J. Squires²
¹School of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA, ³Clinic for Special Children, Strausburg, PA
*Purpose: Determine outcomes and branch-chain amino acid (BCAA - leucine [LEU], isoleucine [ISO], and valine [VAL]) levels at 1-3, 4-7, and 8-10 years for patient’s…
2020 American Transplant Congress
Combining Pharmacy and Genome-Wide Genotyping Data to Examine Medication Regimen Complexity Indices (MRCI), Drug-Drug and Gene-Drug Interactions in Transplant Patients
L. Callans, J. Obayemi, H. Gao, A. Shaked, B. Chang, B. Keating
Penn Transplant Institute, Hospital of the University of Pennsylvania, Philadelphia, USA, Philadelphia, PA
*Purpose: Polypharmacy, typically defined as the use of five or more medications, is a barrier to adherence, and the resulting complex medication regimens result in…
2020 American Transplant Congress
The Impact of DSA Screening in Stable Kidney Transplant Recipients in the 1st Year Post-Transplant
A. Sharma¹, D. Jorgensen², R. Mehta¹, P. Sood¹, C. Wu¹, C. M. Puttarajappa¹, A. Tevar¹, S. Hariharan¹
¹Thomas E. Starzl Transplant Institute, Renal Electrolyte Division, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Thomas E. Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The importance of Donor Specific Antibody (DSA) as a screening tool within the 1st year post kidney transplant in stable patients remains unclear. We…
2020 American Transplant Congress
Allograft Parenchymal Cell Expression of Tlr9 is Required for Endogenous Donor-Reactive Memory Cd8 T Cell Activation within High-Risk Cardiac Allografts to Mediate Ctla-4 Ig Resistant Graft Rejection
D. Ueda, H. Tsuda, S. Miyairi, R. L. Fairchild
Lerner Reserch Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Increased ischemia-reperfusion graft inflammation provokes activation of endogenous donor-reactive memory CD8 T cells within complete MHC-mismatched cardiac allografts at 24 hrs after graft reperfusion…