ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Vira-ome: A Tool for an Unbiased Plasma Virome Analysis of SOT Recipients from Cell-Free DNA Sequences

    R. Sinha, E. Bixler, J. Grantham, M. Altrich, S. Kleiboeker

    R&D, Viracor-Eurofins, Lee's Summit, MO

    *Purpose: Blood virome of healthy individuals is frequently predominated by member of families such as Herpesvirus, Anellovirus and Polyomaviridae. The viral load of commensal species…
  • 2020 American Transplant Congress

    Real-World Experiences in the Transplantation of Hepatitis C Positive Kidneys

    J. M. Steinbrink, J. Byrns, L. Crona, M. Ellis, S. Sanoff, E. K. Maziarz, C. R. Wolfe

    Duke University, Durham, NC

    *Purpose: With advancements of direct-acting antivirals, transplantation of HCV-NAT+ (HCV+) organs to HCV-negative (HCV-) recipients has been used to decrease wait times without apparent sacrifice…
  • 2020 American Transplant Congress

    Organ and Tissue Donation Education for Transplant Patients Staying at a Transplant Hospitality House Leads to Successful Cornea Donation

    T. Giordano1, L. Suplee2, J. L. Weinstock3, R. D. Hasz4, H. M. Nathan5

    1Family Support Manager, Caregiver Lifeline Program, Gift of Life Family House, Philadelphia, PA, 2Director, Transplant Information Center, Gift of Life Donor Program, Philadelphia, PA, 3Vice President and General Counsel, Gift of Life Donor Program, Philadelphia, PA, 4Vice President of Clinical Services, Gift of Life Donor Program, Philadelphia, PA, 5President and CEO, Gift of Life Donor Program, Philadelphia, PA

    *Purpose: A transplant hospitality house (THH) serving multiple transplant centers is directly connected to its region’s Organ Procurement Organization (OPO) and offers formal education to…
  • 2020 American Transplant Congress

    Assessment of HEALTh LIteracy on MEdication ADheREnce and Graft Outcomes in KIdney Transplant Recipients (Hallmark)

    M. Leung1, A. Dhanda2, S. Kwan3, A. Zienkiewicz3, E. Waters3, N. Wood3, L. Young3, C. Bannon3

    1Pharmacy, St. Paul's Hospital, Vancouver, BC, Canada, 2Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 3Nephrology, St. Paul's Hospital, Vancouver, BC, Canada

    *Purpose: Upon successful kidney transplantation, many patients have difficulty adhering to their new immunosuppression medication regimens. Previous studies have established low health literacy to be…
  • 2020 American Transplant Congress

    Impact of Immunosuppression on Quality of Life among HLA-Identical Living Kidney Recipients at UCLA – A Qualitative Study

    E. L. Wood1, S. George2, N. Kogut1, E. Lum, MD3, J. L. Veale1

    1Urology, UCLA, Los Angeles, CA, 2Fielding School of Public Health, UCLA, Los Angeles, CA, 3Medicine, Nephrology, UCLA, Los Angeles, CA

    *Purpose: Tolerant kidney transplant recipients (off immunosuppression) report higher self-rated quality of life and a lower symptom burden compared to standard living recipients when using…
  • 2020 American Transplant Congress

    The Reperfusion Response in Plasma of Combined Heart/ Lung Transplanted Patients is Guided by Heart-Associated Cytokine Patterns on Contrast to the Ischemic Injury in Perfusion Solutions Following a Lung-Associated Pattern

    C. Falk1, J. Kühne2, L. Radomsky2, F. Wandrer2, B. Wiegmann3, N. Ledwoch2, J. Keil2, K. Beushausen2, F. Ius3, W. Sommer3, S. Rojas-Hernandez3, I. Tudorache3, A. Haverich3, G. Warnecke3

    1MHH, Institute of Transplant Immunology, Hannover, Germany, 2Institute of Transplant Immunology, Hannover Medical School MHH, Hannover, Germany, 3Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School MHH, Hannover, Germany

    *Purpose: Organ-specific differences are discussed for ischemia/reperfusion injury (IRI) in cardiothoracic transplantation but rarely compared directly in a clinical setting. Therefore, we compared a cohort…
  • 2020 American Transplant Congress

    Outpatient Treatment of Paramyxovirus with Oral Ribavirin is Safe and Effective in Lung Transplant Recipients

    A. W. Rogers1, B. J. Pierce1, C. Pham1, J. T. Swan1, H. J. Huang2

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: Respiratory paramyxovirus infections present an increased risk to lung transplant recipients (LTRs), including rapid decline in graft function and immunologic sequelae such as rejection…
  • 2020 American Transplant Congress

    Epidemiology of Invasive Candidiasis in Lung Transplant Recipients at a Large Transplant Center

    F. J. Marco Canosa1, J. A. Morillas1, H. Hassouna2, K. Brizendine1

    1Infectious Disease Department, Cleveland Clinic Foundation, Cleveland, OH, 2Division of Infectious Disease, Spectrum Health Medical Group, Grand Rapids, MI

    *Purpose: Invasive candidiasis (IC) represents the most common fungal infection in lung transplant recipients (LTR) early post-transplant. Universal antifungal prophylaxis is frequently employed, which may…
  • 2020 American Transplant Congress

    Ion AmpliSeq RNA Expression Panel Evaluated by Next-Generation Sequencing (NGS) Can Detect Genes in Human Formalin-Fixed Paraffin-Embedded Kidney Biopsies to Predict T Cell and Antibody Mediated Rejection in Renal Allografts

    P. Ruiz1, E. Margolles-Clark1, G. Guerra2, A. Mattiazzi2, M. Ortigosa-Goggins2, G. Ciancio1, L. Chen1, G. Burke1

    1Surgery, University of Miami, Miami, FL, 2University of Miami, Miami, FL

    *Purpose: Optimization of effective anti-rejection therapies to prevent allograft rejection and to minimize drug toxicity may be aided by utilizing in situ biomarkers for detection…
  • 2020 American Transplant Congress

    The Composite Molecular and Cellular Instability Score Identifies the Sub-Phenotypes of Histologically Stable Kidney Transplants

    D. Rychkov

    Department of Surgery, BCHSI, University of California San Francisco, San Francisco, CA

    *Purpose: Recent molecular studies have highlighted the unrecognized burden of sub-clinical graft rejection of a histologically stable allograft, defined as transplants with absence of clinical…
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