Am J Transplant, Volume 20, Suppl 3 Archives - Page 34 of 223 - ATC Abstracts

2020 American Transplant Congress
Adenovirus Infection in Kidney Transplant Recipients: A Case Series
S. Anjan, Y. Natori, M. Raja, J. Camargo, J. Simkins, M. Morris, A. Fernandez, G. Ciancio, L. Chen, G. Burke, M. Ortigosa-Goggins, J. Pagan, A. Mattiazzi, G. Guerra, L. Abbo
University of Miami/Jackson Memorial Hospital, Miami, FL
*Purpose: Adenovirus (AdV) is associated with poor outcomes in immunosuppressed patients and data on incidence and management in kidney transplant (KT) recipients is limited. *Methods:…
2020 American Transplant Congress
Reactivation of Murine Polyomavirus Replication by Renal Ischemia-Reperfusion Injury and Immunosuppression
G. Huang¹, Y. Huang¹, X. Chen¹, J. Qiu¹, J. Li¹, G. Li², C. Wang¹, L. Chen¹
¹The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Guangdong Key Laboratory of Laboratory Animal, Guangdong Laboratory Animals Monitoring Institute, Guangzhou, China
*Purpose: Polyomavirus (PyV) nephropathy is an important cause of graft failure after renal transplantation. Its pathogenesis is associated with immunosuppression (IM) and renal ischemia-reperfusion injury…
2020 American Transplant Congress
Optimal Transition for Transplant Recipients: A Model of Care in an Integrated Health Care System
S. Zheng¹, L. Pravoverov¹, A. Nazarova¹, D. Adey², N. B. Goes¹
¹The Permanente Medical Group, San Francisco, CA, ²Kidney and Transplantation Program, University of California San Francisco, San Francisco, CA
*Purpose: Transplantation is the treatment of choice for ESRD. While short-term outcomes have improved, long-term outcomes lag. Many factors may explain the long-term lag including…
2020 American Transplant Congress
Peripheral Blood T- and B-Cells as Predictors of Acute Rejection in Pancreas Transplant Recipients
P. Ventura Aguiar¹, J. Rovira², M. Ramirez-Bajo², E. Bañón-Maneus², N. Hierro², M. Garcia Criado³, M. Cuatrecasas⁴, J. Ferrer⁵, E. Esmatjes⁶, J. Campistol¹, F. Diekmann¹
¹Nephrology and Kidney Transplantation, Hospital Clinic Barcelona, Barcelona, Spain, ²Laboratori Experimental de Nefrologia i Trasplantament, Fundacio Clinic - IDIBAPS, Barcelona, Spain, ³Radiology Department, Hospital Clinic Barcelona, Barcelona, Spain, ⁴Pathology Department, Hospital Clinic Barcelona, Barcelona, Spain, ⁵HepatoBilioPancreatic Surgery Department, Hospital Clinic Barcelona, Barcelona, Spain, ⁶Endocrinology Department, Hospital Clinic Barcelona, Barcelona, Spain
*Purpose: Pancreas transplantation is associated with a high risk of acute rejection. The effect of peripheral blood mononuclear cells (PBMC) on acute rejection (AR) outcomes…
2020 American Transplant Congress
Expression of Multiple Human Complement Regulatory Proteins Results in Prolonged Heterotopic Xenoheart Survival in an NHP Model
K. Ahrens¹, J. M. O¹, W. Sommer², D. Becerra¹, P. M. Patel¹, A. Dehnadi¹, Y. Kan³, J. Layer³, J. Morrissette¹, T. Costa¹, I. M. Hanekamp¹, J. S. Allan⁴, M. Youd³, R. N. Pierson⁵, W. Qin³, L. Burdorf⁵, A. M. Azimzadeh¹, W. Westlin³, L. Yang³, J. C. Madsen⁵
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ³eGenesis Inc., Cambridge, MA, ⁴Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, ⁵Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Advances in genome engineering technology allow for multiplex genetic modifications in pigs designed to address immunologic and coagulation incompatibilities in order to facilitate xenotransplantation.…
2020 American Transplant Congress
Rare HLA DRB1*10-DQB1*06 Linkage Disequilibrium: A Case Study That Emphasizes the Need of Having an HLA Toolbox
S. Dionne, L. Santiago, S. Shetty
VRL-Eurofins, Centennial, CO
*Purpose: This case study highlights the need to use different tools to derive and validate HLA typing results especially in instances of rare typing.*Methods: Low/intermediate…
2020 American Transplant Congress
The Development of an Innovative Training Pathway for Robotic Assisted Renal Transplant Program
H. Pournik¹, J. Castillo², V. Brown², J. Collins², C. Haisch², D. Leeser²
¹ECU, Greenville, NC, ²Surgery, East Carolina University, Greenville, NC
*Purpose: To develop and implement a surgeon and team training program for robotic renal transplants utilizing innovative technology and techniques.*Methods: A graduated robotic educational program…
2020 American Transplant Congress
Age- and Sex-Mediated Differences in T Lymphocyte Populations of Kidney Transplant Recipients
R. Dziarmaga¹, D. Ke¹, V. Phan², H. Cardinal³, R. Sapir-Pichhadze¹, C. A. Piccirillo¹, B. Mazer¹, B. Foster¹
¹Research Institute - McGill University Health Centre, Montreal, QC, Canada, ²Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada, ³Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada
*Purpose: Kidney allograft failure rates peak between 17 to 24 years of age and are higher in young female than male kidney transplant recipients (KTR).…
2020 American Transplant Congress
Unique Genomic & Proteomic Profile of Liver Mesenchymal Stromal Cells is Associated with Their Superior Immunomodulatory Properties
F. Yigitbilek, W. D. Park, N. Abrol, M. D. Stegall, T. Taner
Transplant Center, Mayo Clinic, Rochester, MN
*Purpose: Investigating mechanisms of liver allografts’ relative tolerance, we recently reported that liver mesenchymal stromal cells (L-MSC) are superior in their capacity to inhibit alloimmune…
2020 American Transplant Congress
Characterization of Laminin Alpha 4 Conditional Knockout Mice: Model for Immune Stimulation
M. W. Shirkey, L. Li, W. Piao, Y. Xiong, V. Saxena, T. Zhang, C. Paluskievicz, J. Bromberg
U. Maryland, Baltimore, MD
*Purpose: Lymph node (LN) stromal laminin α4 (Lama4) and α5 (Lama5) are associated with tolerance and immunity, respectively. We created a Lama4 conditional knockout (KO)…