ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Kidney Procurement Biopsy Technique Does Not Determine Histologic Accuracy

    V. Shah, K. King, S. Coley, G. Dube, D. Cohen, S. Mohan, S. Husain

    Medicine-Nephrology, Columbia University, New York, NY

    *Purpose:Procurement biopsies (PBx) are commonly used to evaluate the quality of deceased donor kidneys (DDK). However, the validity of PBx biopsy interpretation has been questioned,…
  • 2020 American Transplant Congress

    The Effects of DGF after Deceased Donor Renal Transplantation Differ by KDPI

    M. Molinari1, W. Chang1, D. Jorgensen2, C. Wu3, S. Hariharan3

    1Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, 2Biostatistics, University of Pittsburgh Medical Centre, Pittsburgh, PA, 3Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA

    *Purpose: We analyzed the effects of DGF on: (1) graft survival, (2) patient survival and (3) eGFR of adult recipients of deceased donor kidney transplants…
  • 2020 American Transplant Congress

    Adult Living Donor Liver Transplantation Results in Superior Patient and Graft Survival When Compared to Deceased Donor Liver Transplantation: A Systematic Review and Meta-Analysis

    A. Barbetta1, M. Aljehani2, M. KIM1, C. Tien3, A. Ahearn1, H. Schilperoort2, L. Sher1, J. Emamaullee1

    1Surgery, abdominal transplat, University of Southern California, Los Angeles, CA, 2University of Southern California, Los Angeles, CA, 3Surgery, abdominal transplat, Keck Medical School, University of Southern California, Los Angeles, CA

    *Purpose: Center-specific or national registry studies have shown that living donor liver transplantation (LDLT) decreases waitlist mortality, reduces waiting time, and may offer superior patient…
  • 2020 American Transplant Congress

    Using Artificial Intelligence Tools for Identification of High Risk Transplant Recipients for Focused Management

    M. A. Schnitzler1, C. Dagli2, C. Canfield2, N. Dzebisashvili3, C. Varma1, D. Axelrod4, K. Lentine1, R. Ouseph1, H. Randall1

    1Saint Louis University, St. Louis, MO, 2Missouri S&T, Rolla, MO, 3CareDx, Brisbane, CA, 4University of Iowa, Iowa City, IA

    *Purpose: Resources for post-transplant patient monitoring are limited. Statistical stratification can facilitate focused attention on highest risk patients. We developed a monitoring tool for graft…
  • 2020 American Transplant Congress

    Simultaneous Pancreas-Kidney Transplantation in Caucasian versus African American Patients: Does Recipient Ethnicity Influence Outcomes?

    J. Rogers1, A. Farney1, G. Orlando1, C. Jay1, V. Gurram1, K. Gurung1, A. Reeves-Daniel2, A. Mena-Gutierrez2, N. Sakhovskaya2, M. Gautreaux1, R. Stratta1

    1Department of Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, 2Department of Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC

    *Purpose: The influence of African American (AA) recipient ethnicity on outcomes following simultaneous pancreas-kidney transplantation (SPKT) in the modern era is uncertain.*Methods: From 11/01 to…
  • 2020 American Transplant Congress

    Multiplexed Imaging Mass Cytometry Analysis Reveals a New Role for CD68+ Macrophages in Chronic Liver Transplant Rejection

    J. Emamaullee, C. Man, J. Hoeflich, N. Ung, R. Sun, N. Matasci, J. Katz, J. Lee, S. Chopra, L. Sher, S. Asgharzadeh, O. Akbari, Y. Genyk

    University of Southern California, Los Angeles, CA

    *Purpose: Rejection continues to be an important cause of graft loss and failure post-liver transplant (LT). Recently, a novel high-resolution mass spectrometry-based technique has been…
  • 2020 American Transplant Congress

    Characterizing the Impact of Medicaid Expansion on Pediatric Liver Transplantation

    J. D. Motter, A. Kernodle, D. L. Segev, A. B. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: Under the Patient Protection and Affordable Care Act (ACA), states have the option to expand Medicaid eligibility (ME) which has allowed for increased access…
  • 2020 American Transplant Congress

    Trends in Time to Graft Loss by Dialysis Vintage

    P. Ahearn, C. Lenihan, J. Scandling

    Stanford University, Palo Alto, CA

    *Purpose: Preemptive transplantation has been shown to be beneficial regarding all-cause graft failure compared to transplantation after dialysis initiation, and transplantation after a shorter time…
  • 2020 American Transplant Congress

    Costimulatory Signal Impacts Car Treg Fate and Function in Transplantation

    B. Lamarthée1, A. Marchal1, S. Charbonnier1, T. Blein1, K. Vogt2, M. Titeux1, N. Pallet3, M. Delville1, E. Six1, D. Anglicheau4, C. Legendre4, B. Sawitzki2, J. Taupin5, M. Cavazzana1, I. André1, J. Zuber1

    1Inserm U1163, Institut Imagine, Paris, France, 2Department of Immunology, Charité University Hospital, Berlin, Germany, 3Inserm U1147, Centre Universitaire des Saints Pères, Paris, France, 4Service de Transplantation Rénale Adulte, Assistance Publique–Hôpitaux de Paris, Hôpital Necker, Paris, France, 5Inserm U1160, Centre Hayem, Paris, France

    *Purpose: Donor-specific regulatory T-cell (Treg) therapy has emerged as a potent strategy to promote immune tolerance in experimental transplantation. However, a major stumbling block in…
  • 2020 American Transplant Congress

    Re-Establishing Abstinence after Alcohol Relapse after Early Transplant (LT) for Alcoholic Hepatitis (AH) Provides Survival Advantage

    J. Rice1, B. Lee2, G. Therapondos3, G. Im4, A. Lazar2, M. Lucey1, E. Weinberg5, H. Han6, H. Maddur7, M. Ghobrial8, C. Hsu9, O. Fix10, S. Eswaran11, K. Shetty12, N. Jakhete12, D. Victor8, D. Foley1, N. Mehta2, M. Rinella7, T. Schiano4, C. Mobley8, N. Terrault6

    1U of WI SMPH, Madison, WI, 2UCSF, San Francisco, CA, 3Oschner, New Orleans, LA, 4Mt Sinai, New York, NY, 5U Penn, Philadelphia, PA, 6USC, Los Angeles, CA, 7NW Univ, Chicago, IL, 8Houston Mdt, Houston, TX, 9GTown U, Washington, DC, 10Swed Med, Seattle, WA, 11Rush Med C, Chicago, IL, 12U of MD, Baltimore, MD

    *Purpose: Among the ACCELERATE-AH cohort: (i) Identify factors associated with re-established abstinence in patients with alcohol relapse after LT for alcoholic hepatitis (AH); (ii) Determine…
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