Am J Transplant, Volume 20, Suppl 3 Archives - Page 3 of 223 - ATC Abstracts

2020 American Transplant Congress
Understanding the Molecular Phenotype of Kidney Injury
J. Reeve¹, P. Halloran¹, &. the INTERCOMEX Study Group²
¹University of Alberta, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: The injury status of transplanted organs is a strong predictor of graft loss. We used injury-related gene expression to explore the relationship between function,…
2020 American Transplant Congress
A Single Centre Report of Renal Transplantation Against a Positive Crossmatch Due to HLA-DP Donor Specific Antibodies without Prior Antibody Removal
Y. Marie¹, T. Key², A. Halawa¹
¹Renal Transplantation, Sheffield Kidney Institute, Sheffield, United Kingdom, ²2.Department of Histocompatibility and Immunogenetics, Sheffield, United Kingdom
*Purpose: In renal transplantation, the clinical effects of donor specific antibodies (DSA) against HLA-DP are unclear. We report successful kidney transplants in three highly sensitised…
2020 American Transplant Congress
Survival Benefit of Accepting Kidneys with Acute Kidney Injury
Y. Yu, J. Long, M. Bowring, S. Yu, J. Motter, T. Ishaque, J. Garonzik Wang, A. Massie, D. Segev
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Accepting an acute kidney injury kidney (AKI) or remaining on the waitlist to receive a better offer is under discussed due to the worse…
2020 American Transplant Congress
Pediatric Primary Kidney Transplant Recipients Outcomes by Immunosuppression Induction Received in the United States
S. M. Riad¹, S. Jackson², A. Matas³, S. Chinnakotla³, P. Verghese⁴
¹University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN, ⁴Pediatrics, University of Minnesota, Minneapolis, MN
*Purpose: Induction immunosuppression types for pediatric transplant recipients vary widely by transplant centers. We sought to study the impact of different induction types on recipients…
2020 American Transplant Congress
Risk Factors for Antibody-Mediated Rejection after Adult Liver Transplantation with Preformed Donor-Specific Antibodies: A Single Center Experience
T. Tajima, K. Hata, J. Kusakabe, H. Miyauchi, T. Anazawa, T. Ito, S. Uemoto
Div. of HBP Surgery and Transplantation, Dept. of Surgery, Kyoto University, Kyoto, Japan
*Purpose: In general, preformed donor-specific antibodies (pDSAs) can lead to an increased risk of antibody-mediated rejection (AMR); however, their prevalence, risk factors, and the efficacy…
2020 American Transplant Congress
Effectiveness of Routine Screening for Mycoplasma Hominis and Ureaplasma spp. in Lung Transplant Recipients
P. Vijayvargiya, Z. Esquer Garrigos, C. C. Kennedy, R. C. Daly, M. E. Wylam, E. Beam
Mayo Clinic, Rochester, MN
*Purpose: In lung transplant recipients Mycoplasma hominis and Ureaplasma spp. may cause localized or disseminated infection and fatal hyperammonemia syndrome (HS). Optimal prevention strategies are…
2020 American Transplant Congress
Sirolimus Plus Tacrolimus Immunosuppression, with or without Mycophenolate Mofetil, May Improve Survival after Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
M. Wijesinha, M. Terrin, B. Griffith, A. Iacono
University of Maryland School of Medicine, Baltimore, MD
*Purpose: There are very few ways to improve survival after bronchiolitis obliterans syndrome (BOS), the leading cause of death in lung transplant patients. Two long-term…
2020 American Transplant Congress
HLA-DR/DQ Molecular Mismatch Dictates Early Risk of De Novo Donor-Specific Antibody Development and Offers a Personalized Approach to Immunosuppression Management in Kidney Transplantation
S. Davis¹, C. Wiebe², K. Campbell¹, C. Anobile³, M. Aubrey³, A. Wiseman¹, E. Pomfret¹, P. Nickerson², J. Cooper¹
¹University of Colorado, Aurora, CO, ²University of Manitoba, Winnipeg, MB, Canada, ³Clinimmune, Aurora, CO
*Purpose: Clinicians have few tools to predict the risk of alloimmune injury in a patient undergoing renal transplantation, as traditional demographic or clinical variables lack…
2020 American Transplant Congress
TRANSFORM Study (NCT01950819): Application of the Ibox Clinical Trial Simulation Tool to Project Long-Term Kidney Allograft Outcome
G. Divard¹, O. Aubert¹, M. Raynaud¹, J. Pascual², F. Vincenti³, P. Bernhardt⁴, C. Legendre¹, A. Loupy¹, .. on behalf of TRANSFORM Investigators⁵
¹INSERM U970, Paris Transplant Group, Paris, France, ²Department of Nephrology, Hospital del Mar/Universitat Autònoma de Barcelona, Barcelona, Spain, ³Department of Surgery/Kidney Transplant Service, University of California, San Francisco, CA, ⁴Research and Development, Novartis Pharma AG, Basel, Switzerland, ⁵TRANSFORM Investigators, Basel, Switzerland
*Purpose: The development of pharmaceutical agents in transplantation is currently limited by long waits for hard endpoints. We sought to use a risk stratification system…
2020 American Transplant Congress
Your Path to Transplant Tailored Education Increases Living Donation Transplant Actions and Wait-Listing Rates: Final Randomized Controlled Trial Findings
A. Waterman¹, Y. Cui², J. L. Beaumont², J. D. Peipert³, A. Paiva⁴, M. L. Robbins⁴
¹Transplant Research and Education Center, Los Angeles, CA, ²Terasaki Research Institute, Los Angeles, CA, ³Feinberg School of Medicine, Northwestern University, Chicago, IL, ⁴Department of Psychology, University of Rhode Island, Kingston, RI
*Purpose: Tailoring education and behavior change interventions to address gaps in individual patients’ knowledge, readiness, and socio-economic challenges may help more end-stage kidney disease patients…