Am J Transplant, Volume 20, Suppl 3 Archives - Page 24 of 223 - ATC Abstracts

2020 American Transplant Congress
Improvements in Organ Donation: Riding the Coattails of a National Tragedy
D. Goldberg¹, R. Lynch²
¹Medicine, University of Miami, Miami, FL, ²Emory University, Atlanta, GA
*Purpose: The US organ donation system has received attention from the highest levels of government. It has been debated whether increased donation is attributable solely…
2020 American Transplant Congress
Investigating the 6-Month Effects of the UNOS Allocation System Changes on the Post Transplant Outcomes in Patients with Amyloidosis
P. Banankhah¹, G. Liu¹, J. Nattiv¹, C. Lum², A. Salimbangon³, A. Wolfson⁴, E. DePasquale¹, R. Chand⁵, P. Genyk¹, P. Kingsford¹, J. Li¹, D. Vucicevic⁶, A. Vaidya¹, K. Pandya¹, J. Rahman¹, M. Fong¹, L. Grazette¹, A. Kiankhooy¹, S. Hashmi¹, S. Nuno¹, J. Pizula¹, D. Miklin¹, A. E. Lee¹, K. Yang¹, S. Shah¹
¹Cardiology, University of Southern California, Los Angeles, CA, ²Cardiology, The Queen's Medical Center, Honolulu, HI, ³Cardiology, UCLA Medical Center, Los Angeles, CA, ⁴Cardiology, University of Arizona Sarver Heart Center, Tucson, AZ, ⁵Cardiology, Harbor-UCLA Medical Center, Los Angeles, CA, ⁶Cardiology, Newark Beth-Israel Medical Center, Newark, NJ
*Purpose: Cardiac amyloidosis is an infiltrative cardiomyopathy with poor outcomes. Cardiac transplantation and increased utilization of mechanical support have led to improved outcomes in patients…
2020 American Transplant Congress
Combined Heart-Liver Transplantation: A Systematic Review of the Literature
I. A. Ziogas¹, D. Giannis², P. Kapsampelis², A. Giannopoulou², A. Evangeliou², K. S. Mylonas², G. Tsoulfas³, L. K. Matsuoka¹, M. I. Montenovo¹, M. Izzy¹, S. P. Alexopoulos¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Society of Junior Doctors, Athens, Greece, ³Aristotle University of Thessaloniki, Thessaloniki, Greece
*Purpose: Combined heart-liver transplant (CHLT) has been increasingly utilized as the treatment of choice for candidates with dual end-stage organ disease. We aimed to assess…
2020 American Transplant Congress
Lung Transplantation for Patients with Pneumoconiosis in China: A Multicenter Experience from 2015-2019
J. Zhang¹, D. Liu¹, W. Han², J. Chen¹
¹Lung Transplant Center, Wuxi People's Hospital, Wuxi, China, ²Lung Transplant Center, 1st Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
*Purpose: The pneumoconiosis are parenchymal lung diseases that arise from inhalation of dusts. And lung transplantation is an effective method for the treatment of end-stage…
2020 American Transplant Congress
Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center
A. Modi¹, B. Gonzalez², K. Brizendine¹
¹Infectious Disease, Cleveland Clinic, Cleveland, OH, ²Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH
*Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
2020 American Transplant Congress
T Cell Hyporesponsiveness in Kidney Transplant Recipients is Associated with Urinary Tract Infections and Age of Kidney Transplant: Implications for Allograft Nephropathy
A. Assounga, S. Omarjee
Dept of Nephrology, University of KwaZulu-Natal, Durban, South Africa
*Purpose: Chronic allograft nephropathy is the main cause of kidney graft loss. With the use of potent immunosuppressive treatments, acute rejections are less and less…
2020 American Transplant Congress
ANG-3777, A Hepatic Growth Factor Mimetic, Attenuates Post-Transplant Renal Dysfunction in Rats
P. Narayan, I. D. Goldberg
Angion Biomedica, Uniondale, NY
*Purpose: ANG-3777, a small-molecule mimetic of hepatocyte growth factor (HGF), has the potential to exert antifibrotic and nephroprotective effects. A rat model of renal transplantation…
2020 American Transplant Congress
Targeting CD4⁺ T Cell Metabolism Prolongs Graft Survival Age-Specifically
Y. Nian, J. Iske, K. Minami, R. Maenosono, T. Heinbokel, A. Elkhal, S. G. Tullius
Division of Transplant Surgery and Transplant Surgery Research Laboratory, Harvard Medical School, Boston, MA
*Purpose: If and how aging affects T-cell metabolism and alloimmune response is unclear. Here, we show that T-cell metabolism changes drastically in aging. Most notably,…
2020 American Transplant Congress
Identification of Cell Types That Harbor Cytomegalovirus DNA in Acutely and Latently Infected Mice Spleen
A. S. Maganti¹, X. Liu², M. Abecassis²
¹Illinois Math and Science Academy, Aurora, IL, ²Comprehensive Transplant Center, Northwestern University, Chicago, IL
*Purpose: Cytomegalovirus (CMV) is a ubiquitous β‐herpesvirus that infects majority of humans. Primary CMV infection may be asymptomatic or manifests as a self‐limited febrile illness…
2020 American Transplant Congress
Adaptive Induction Therapy in Renal Transplant Recipients (RTR) with Donor-Specific Antibody (DSA)
K. Linhares¹, M. Cristelli², R. De Marco³, L. Viana², C. Felipe², M. Tavares², C. Peixoto², G. Marcello², J. Toniato², K. Ficher², L. Villanueva², L. Villanueva², M. De Lima³, J. Pestana², H. Tedesco Jr.²
¹Nephrology Division, Hospital do Rim, Sao Paulo, Brazil, ²Nephrology Division, Hospital Do Rim, Sao Paulo, Brazil, ³Histocompatibility Laboratory, Instituto De Imunogenética IGEN, Sao Paulo, Brazil
*Purpose: Patients with preformed DSA are at higher risk of developing acute antibody-mediated rejection (ABMR) after kidney transplantation.*Methods: We analyzed consecutive kidney transplant recipients (RTR)…