ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    IL-21, a Potential Target of Active Rejection in Renal Transplantation

    J. Shen, R. Wang, L. Guo, J. Lv, J. Wu, J. Chen

    Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China

    *Purpose: Rejection remains an obstacle to overcome after transplantation. IL-21 is the most potent stimulators of driving GC B cells into plasma cells. Basic researches…
  • 2020 American Transplant Congress

    Impact of Liver Graft Preservation Methods on the Gut Microbiome and Metabolome

    G. A. Cresci1, N. Sangwan2, A. Simioni3, Q. Liu3, C. Quintini3

    1Pediatric Gastroenterology and Inflammation & Immunity, Cleveland Clinic, Cleveland, OH, 2Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 3Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH

    *Purpose: Normothermic ex-vivo liver perfusion (NEVLP) is a powerful platform for organ preservation and assessment. It induces metabolic reactivation that potentially helps clear accumulated toxic…
  • 2020 American Transplant Congress

    Routine Human Renal Allograft Biopsies Analyzed for mRNA Content with a Novel Nanostring mRNA Human Organ Transplant (HOT) Panel

    I. Rosales1, R. Smith1, E. Acheampong1, T. Kawai1, T. Tsuji2, K. Hotta3, R. Colvin1

    1Massachusetts General Hospital, Boston, MA, 2Sapporo City General Hospital, Sapporo, Japan, 3Hokkaido University Hospital, Sapporo, Japan

    *Purpose: In 2019 a Banff Working Group and Nanostring Technologies developed a panel of 770 mRNA probes for assessment of human organ allografts, based on…
  • 2020 American Transplant Congress

    Rabbit Anti-Thymocyte Globulin versus Anti-T Lymphocyte Globulin Rescue Therapies in Delayed Graft Function after Kidney Transplantation from Donors after Cardiac Death

    H. Yang1, Y. Shi2, X. Li1, C. Long1, H. Li3, Z. Wang3

    1Department of Organ Transplantation, Jiangxi Provincial People’s Hospital Affiliated to Nanchang University, Nanchang, China, 2Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 3Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    *Purpose: Delayed graft function (DGF) is common in recipients of kidney transplants from donation after cardiac death (DCD) donors, induction therapy with monoclonal or polyclonal…
  • 2020 American Transplant Congress

    Increased Graft Survival Following Implementation of the Kidney Allocation Score

    M. L. Samoylova1, B. I. Shaw1, W. Irish2, S. J. Kesseli1, A. Connor1, A. S. Barbas1, L. McElroy1, K. V. Ravindra1

    1Surgery, Duke University Hospital, Durham, NC, 2Surgery, East Carolina University, Greenville, NC

    *Purpose: The Kidney Allocation Score (KAS) was developed to improve matching of donor and recipients; we examine the effect of this change on transplantation practice…
  • 2020 American Transplant Congress

    Impact of Chronic Changes on Preimplantation Biopsy (PBx) on Outcomes after Deceased Donor Kidney Transplantation (DDKTx)

    J. Ninan, R. Heilman, M. Smith, J. Harbell, S. S. Nair, C. Jadloweic, H. Khamash, A. Moss, K. S. Reddy

    Mayo Clinic, Phoenix, AZ

    *Purpose: The value of PBx is unclear. The aim of this study was to determine the prognostic value of chronic changes on PBx on graft…
  • 2020 American Transplant Congress

    Improving Vaccination Rates for Influenza and Pneumococcal Disease in Pediatric Kidney Transplant Recipients

    A. M. McGrath1, J. Baquir1, L. Maestretti1, G. James1, K. DiNello1, M. Patton1, A. Fong1, A. Gallo2, V. Sigurjonsdottir2, P. Grimm2, A. Chaudhuri2

    1Pediatric Kidney Transplant, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 2Pediatric Kidney Transplant, Stanford University, Palo Alto, CA

    *Purpose: Pediatric renal transplant recipients are highly vulnerable to infections caused by influenza and pneumococcus and vaccines are recommended in this population. At our center,…
  • 2020 American Transplant Congress

    Mid-Term Outcomes after Treatment for Antibody-Mediated Rejection by De Novo Donor-Specific HLA Antibody in Renal Transplant Recipients: Does Early Treatment Lead to Better Outcomes?

    M. Okada1, T. Tomosugi1, T. Hiramitsu1, S. Narumi1, Y. Watarai1, A. Kanda1, K. Futamura1, N. Goto1, A. Takeda2

    1Nagoya Daini Red Cross Hospital, Nagoya, Japan, 2Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Japan

    *Purpose: De novo donor-specific HLA antibody (DSA) and antibody-mediated rejection (ABMR) are strongly associated with late allograft loss in renal transplant recipients. However, the impact…
  • 2020 American Transplant Congress

    Multi- National Survey among Nephrologists and Transplant Surgeons about the Suitability and Acceptance of the Marginal Live Kidney Donors with Family History of Kidney Disease

    Z. Arabi1, S. Kaysi2, A. Altheaby1, E. Elhassan1, M. Bukhari3, A. Mateen1, A. Hamad4

    1KAMC, Riyadh, Saudi Arabia, 2CHR Orleans, Orleans, France, 3Taif University, Taif, Saudi Arabia, 4The Regional Medical Center, Orangeburg, SC

    *Purpose: Kidney transplantation from a living donor is the best treatment option for End Stage Kidney Disease. Considering the shortage of available organs, transplant centers…
  • 2020 American Transplant Congress

    Predictors of Kidney Transplant Evaluation Attendance

    C. G. Ford1, Y. Leyva1, Y. Zhu2, E. J. Croswell3, C. Puttarajappa4, M. A. Dew3, M. L. Unruh2, Y. Ng2, L. Myaskovsky1

    1Center for Healthcare Equity in Kidney Disease, University of New Mexico Health Sciences Center, Albuquerque, NM, 2University of New Mexico School of Medicine, Albuquerque, NM, 3University of Pittsburgh, Pittsburgh, PA, 4University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: Given that clinic non-attendance is associated with worse health outcomes for patients and increased burden for providers, we examined whether patient worry about harm…
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