Am J Transplant, Volume 20, Suppl 3 Archives - Page 214 of 223 - ATC Abstracts

2020 American Transplant Congress
IL-6 Receptor Blockade But Not IL-2 Treatment Contributes to Long-Term NHP Cardiac Allograft Survival in Transient Mixed Chimeras
K. Ahrens¹, J. M. O¹, W. Sommer², J. Morrissette¹, D. Becerra¹, P. M. Patel¹, T. Costa¹, A. Dehnadi¹, I. M. Hanekamp¹, J. S. Allan³, G. Benichou¹, J. C. Madsen⁴
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, ³Center for Transplantation Sciences, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, ⁴Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: Long-term tolerance of cardiac allografts has been achieved in non-human primates (NHPs) using a mixed chimerism protocol and by co-transplanting a kidney from the…
2020 American Transplant Congress
Safety Outcomes in Lower-Weight vs Higher-Weight Recipients of Fixed Dose Alemtuzumab for Kidney Transplant Induction
A. Freeman, S. Anders, B. Wise, M. Janusek, L. Hutchinson, U. Kaszubski, D. Marroquin, D. Martin, H. Bohorquez
Ochsner Medical Center, New Orleans, LA
*Purpose: Alemtuzumab is a lymphocyte-depleting monoclonal antibody used for renal transplant induction, and is associated with significant leukopenia, increased infections and malignancy. Multiple dosing strategies…
2020 American Transplant Congress
Antibody-Mediated Rejection with and without Donor-Specific Anti-HLA Antibodies: Performance of the Peripheral Blood 8-Gene Expression Assay
E. Van Loon¹, E. Lerut², D. Anglicheau³, W. Gwinner⁴, M. Essig⁵, P. Marquet⁵, M. Naesens¹
¹Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ²KU Leuven, Leuven, Belgium, ³Department of Nephrology and Kidney Transplantation, Necker Hospital, Paris, France, ⁴Hannover Medical School, Hannover, Germany, ⁵CHU Limoges, Limoges, France
*Purpose: Therapeutic implications of the recently discovered 8-gene expression assay are most clear for detection of antibody-mediated rejection in presence of donor-specific anti-HLA antibodies (HLA-DSA).…
2020 American Transplant Congress
The Effect of Intravenous Acetaminophen on Opioid Use in Laparoscopic Donor Nephrectomy Patients
C. Makosiej, A. Eisenhart
Saint Barnabas Medical Center, Livingston, NJ
*Purpose: The purpose of this study was to determine if intravenous acetaminophen (IV APAP) use affects the daily and cumulative opioid requirements of patients undergoing…
2020 American Transplant Congress
Geographic Variation in Characteristics of High-KDPI Donors
G. R. Vece¹, A. Wilk¹, N. Turgeon²
¹United Network for Organ Sharing, Richmond, VA, ²Dell Seton Medical Center, Austin, TX
*Purpose: The kidney donor profile index (KDPI) was incorporated into kidney allocation in the United States in 2014, and discard rates for high-KDPI donors (86-100%)…
2020 American Transplant Congress
Association of Congenital Anomalies of the Kidney and Urinary Tract with Urinary Tract Infection and Graft Rejection in Pediatric Kidney Transplant Recipients
M. Bock, D. Han, A. Sikora, K. Mckinnon, S. Hecht, M. Chandran, V. Vemulakonda
Children's Hospital Colorado, Denver, CO
*Purpose: Congenital anomalies of the kidney and urinary tract (CAKUT) are a leading cause of pediatric end-stage renal disease (ESRD). Prior studies have shown an…
2020 American Transplant Congress
Kidney Transplant Recipient Outcomes from Older (60+) Hypertensive Living Donors
A. Sharfuddin, T. Taber, O. Adebiyi, M. Panezai, D. Mishler, M. Yaqub
Indiana University School of Medicine, Indianapolis, IN
*Purpose: Although the data supporting long-term safety of nephrectomy in hypertensive donors has been reported, there is scarcity of long term data on the recipient…
2020 American Transplant Congress
Lymphoceles in Kidney Transplant Recipients: Incidence, Risk Factors, Outcomes, and Clinical Management
J. Kim, E. Nguyen, M. Minkovich, O. Famure, Y. Li, J. Lee
Toronto General Hospital, Toronto, ON, Canada
*Purpose: Post kidney transplantation, lymphocele development can result in morbidity for the patient and graft. Lacking prior studies in a representative cohort, we aimed to…
2020 American Transplant Congress
The Association between Infection and Important Clinical Outcomes in Acute-On-Chronic Liver Patients Admitted to ICU: A Single Center Cohort Analysis
M. Kim¹, A. Pawlowski², R. G. Wunderink³, D. P. Ladner⁴, C. J. Karvellas⁵
¹Neurology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Medicine, Northwestern University, Chicago, IL, ⁴Surgery, Northwestern University, Chicago, IL, ⁵Medicine, University of Alberta, Edmonton, AB, Canada
*Purpose: One of the most common precipitants of acute on chronic liver failure (ACLF) in cirrhotic patients is sepsis. We aimed to evaluate the relationship…
2020 American Transplant Congress
Evaluation of Rejection, Infection, and Malignancy Outcomes in Elderly Liver Transplant Recipients Compared to a Younger Cohort
B. Almalki¹, K. Cunningham¹, C. D'Agostino¹, M. Kapugi¹, C. Kane¹, A. Novak¹, D. Ladner², J. Schulte¹
¹Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ²Division of Transplant Surgery, Northwestern Memorial Hospital, Chicago, IL
*Purpose: Previous data has shown elderly liver transplant recipients (LTx) to be at a lower risk of acute rejection than younger recipients. As such, elderly…