Am J Transplant, Volume 20, Suppl 3 Archives - Page 213 of 223 - ATC Abstracts

2020 American Transplant Congress
New and Unknown: VCA Acceptability to the General Public
L. A. Siminoff, D. B. Sarwer, G. P. Alolod, E. Davis, H. McGregor, H. M. Gardiner
Social and Behavioral Sciences, Temple University, Philadelphia, PA
*Purpose: Despite the promise of vascularized composite allotransplantation (VCA) as a viable alternative to available reconstructive procedures or prosthetics, its future relies heavily on families’…
2020 American Transplant Congress
Renal Allograft Surveillance with Allospecific T-cytotoxic Memory Cells Which Express CD154
V. Rohan, A. Alqassieh, N. Patel, K. Soliman, V. Rao
Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Allo-antigen-specific T-cytotoxic memory cells (TcM) which express CD40 ligand (CD154) in overnight lymphocyte co-culture are strongly associated with acute cellular rejection (ACR) seen in…
2020 American Transplant Congress
Anti-Thymocyte Globulin Promotes Tfh Cells Differentiation and Alloantibody Production
R. Benedetti Gassen, B. Aoyama, M. Lima, T. Borges, M. Pérez-Sáez, N. Murakami, P. Sage, J. Pascual, L. V. Riella
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
*Purpose: Antibody-mediated rejection is a major cause of long-term graft loss. T follicular helper (Tfh) cell is CD4+ T cell subset that is specialized in…
2020 American Transplant Congress
Pilot Donor App Users Maintain Higher Transplant Rates Than Matched Controls
L. R. Herbst, A. D. Love, P. Chiang, K. Kumar, B. King, A. Massie, J. Garonzik Wang, D. L. Segev, A. M. Cameron
Johns Hopkins University, Baltimore, MD
*Purpose: We previously conducted a pilot study demonstrating that patients who used the Donor App (DA) were 6.6 times more likely to generate a live…
2020 American Transplant Congress
Peak DSA Levels Pre-Transplant but Not at Transplant Predict Graft Survival
A. Y. Choi¹, D. Olaso¹, T. Risoli Jr², M. Kuchibhatla², Z. Fitch³, R. Schmitz³, P. M. Schroder³, A. Jackson³, M. Manook³, J. Yoon³, A. B. Farris⁴, J. Kwun³, S. J. Knechtle³
¹Duke University School of Medicine, Durham, NC, ²Duke Biostatistics, Epidemiology, and Research Design Core, Duke University, Durham, NC, ³Department of Surgery, Duke University Medical Center, Durham, NC, ⁴Department of Pathology, Emory University Hospital, Atlanta, GA
*Purpose: Immunization to major histocompatibility complex (MHC) antigens is a barrier in kidney transplantation (KTx) due to higher risk of antibody-mediated rejection (AMR) and graft…
2020 American Transplant Congress
The Changes of Transaminases, Lactate Dehydrogenase and pH Levels During Normothermic Liver Preservation Correlate with Early Allograft Dysfunction
C. Bogensperger
Department of Visceral, Transplant and Thoracic Surgery, Medical University Innsbruck, Innsbruck, Austria
*Purpose: Normothermic liver preservation (NMP) has become a clinically established tool to preserve livers in a near-physiological environment. Currently, decreasing lactate and physiological pH-levels are…
2020 American Transplant Congress
Belatacept Removal by Plasmapheresis: Kinetics, Dose Adjustments and Clinical Recommendations
S. Tremblay¹, N. Wilson¹, B. Miyagawa², H. Kuzaro¹, A. R. Shields³, R. R. Alloway¹, A. Govil¹, J. Kremer⁴, E. Woodle¹, T. Mizuno², A. A. Vinks²
¹U Cincinnati, Cincinnati, OH, ²Cincinnati Children's, Cincinnati, OH, ³U Cincinnati / Christ Hospital, Cincinnati, OH, ⁴Christ Hospital, Cincinnati, OH
*Purpose: Belatacept (BELA), a protein immunosuppressant, has limited available pharmacokinetic (PK) data. Available PK data, limited to product development analyses, shows moderate intrapatient variability with…
2020 American Transplant Congress
Role of Genetic Studies in Reclassifying Cause of End Stage Kidney Disease among Kidney Transplant Candidates
M. El Ters¹, F. Pinto e Vairo², F. C. Fervenza¹, M. Alexander³, F. G. Cosio¹, H. Amer¹, M. Hogan¹
¹Division of Nephrology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, ²Department of Clinical Genomics, Mayo Clinic, Rochester, MN, ³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: Recent studies evaluating genetic causes of kidney disease have reclassified a subgroup of focal segmental glomerulosclerosis (FSGS) into collagenopathies. This knowledge has implication in…
2020 American Transplant Congress
Outcome of Induction Therapies in Low Sensitized Renal Transplant Recipients with Two HLA DR Mismatch in Tacrolimus Era
K. Soliman¹, T. Fulop¹, A. Osman², H. Ali³
¹Medicine, Medical University of South Carolina, Charleston, SC, ²Medicine, Cairo University, Cairo, Egypt, ³Medicine, Royal Stoke, Royal Stoke, United Kingdom
*Purpose: A mismatch for two HLA DR antigens portends high immunological risk in renal transplant recipients (RTRs). Induction therapies with both rabbit Anti-thymocyte Globulin (r-ATG)…
2020 American Transplant Congress
Comparison of Clinical Characteristics and Outcomes of Early Antibody-Mediated Rejection and Late Antibody-Mediated Rejection after Kidney Transplantation
G. Chen, Z. Wu, C. Wang, X. Liu, Q. Li, L. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Antibody-mediated rejection(AMR) is a major risk factor for graft loss after kidney transplantation. Some AMR appeared within 6 months after kidney transplant, that we…