Am J Transplant, Volume 20, Suppl 3 Archives - Page 21 of 223 - ATC Abstracts

2020 American Transplant Congress
Immune Checkpoint Inhibitor Use in Kidney Transplant Recipients: Rejection Risk, Prevention and Transcriptional Signature in Allograft
N. Murakami¹, G. Reid², A. Weins¹, B. Adam², M. Mengel², L. Riella¹
¹Brigham and Women's Hospital, Boston, MA, ²University of Alberta, Edmonton, AB, Canada
*Purpose: Immune checkpoint inhibitor (ICI) use has changed the landscape of cancer treatment. Several cases of acute rejection in use of ICI have been reported,…
2020 American Transplant Congress
Using Personal Contact with Donors and Recipients to Bridge Disparities in Native American Organ Donation and Transplantation
Y. Kelly¹, J. Trompeta¹, J. Rawlings², T. Bongiovanni¹
¹UCSF, San Francisco, CA, ²Yale, New Haven, CT
*Purpose: Native Americans (NAs) are 3.5 times more likely to suffer from end-stage renal disease than White Americans, yet are 34% less likely to receive…
2020 American Transplant Congress
Affect in Patients Awaiting Heart Transplant
A. Ahmed¹, D. S. Yip², B. W. Hardaway³, B. A. Boilson⁴, T. D. Schneekloth⁵, R. Benzo¹, R. Daly⁶, M. A. Hathcock⁷, B. K. Johnson⁷, K. Thompson⁸, C. C. Kennedy⁹
¹Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, ²Department of Transplantation, Mayo Clinic, Jacksonville, FL, ³Division of Cardiovascular Diseases, Mayo Clinic, Scottsdale, AZ, ⁴Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ⁵Department of Psychiatry, Mayo Clinic, Rochester, MN, ⁶Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, ⁷Department of Health Services Research -Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, ⁸Pulm onary Clinical Research Unit, Mayo Clinic, Rochester, MN, ⁹William J. von Liebig Center for Transplantation and Regenerative Medicine, Mayo Clinic, Rochester, MN
*Purpose: Affect refers to an individual’s emotional response .It may be categorized as positive or negative. Affect in heart transplant candidates is under-explored. We aimed…
2020 American Transplant Congress
Comparison of Six-Month Outcomes in Patients Bridged to Heart Transplantation with Percutaneous Temporary Circulatory Support Before and after the UNOS Allocation System Change
J. Nattiv¹, G. S. Liu¹, P. Banankhah¹, J. Sussex¹, P. Genyk¹, J. Li¹, D. Vucicevic², R. S. Chand³, K. Pandya¹, J. Rahman¹, A. M. Wolfson⁴, A. S. Vaidya¹, E. DePasquale¹
¹Keck Hospital of USC, Los Angeles, CA, ²Newark Beth Israel Medical Center, Newark, NJ, ³Harbor UCLA Medical Center, Los Angeles, CA, ⁴University of Arizona Sarver Heart Center, Tucson, AZ
*Purpose: We report the trends in utilization and outcomes of percutaneous temporary circulatory support (TCS) in the forms of Impella or TandemHeart as a bridge…
2020 American Transplant Congress
Alterations in Left Ventricular Wall Thickness after Cardiac Transplantation
C. K. Alvarez, O. Saeed, S. R. Patel, E. Borukhov, U. Jorde
Advanced Heart Failure, Transplant and Mechanical Circulatory Support, Montefiore Medical Center, Albert Einstein, Bronx, NY
*Purpose: We investigated changes in cardiac wall thickness of donor hearts over time, including the peri-operative OHT period (within 4 days after transplantation) and up…
2020 American Transplant Congress
Monitoring the Removal of Donation Service Area from Lung Allocation
R. R. Goff¹, R. Daly², E. D. Lease³
¹Research, United Network for Organ Sharing, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³University of Washington, Seattle, WA
*Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…
2020 American Transplant Congress
Anticoagulation in Simultaneous Pancreas Kidney (SPK) Transplantation- On What Basis?
J. Gopal, P. Herbert, J. Crane, F. Dor, V. Papalois, A. Muthusamy
Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
*Purpose: Despite technical refinements, early pancreas graft loss due to thrombosis continues to occur. Conventional coagulation tests do not detect hypercoagulability and hence is left…
2020 American Transplant Congress
The Role of Complement-Split Products as Biomarkers for Acute Antibody-Mediated Rejection of Kidney Allografts
B. G. Abu Jawdeh¹, B. Campos-Naciff¹, K. Harrison¹, K. Meganathan¹, A. Kumar², M. Anand¹, A. Govil¹, E. S. Woodle¹, B. P. Dixon³
¹University of Cincinnati, Cincinnati, OH, ²All India Institute of Medical Sciences, New Delhi, India, ³University of Colorado, Aurora, CO
*Purpose: Acute antibody-mediated rejection (AMR) is mediated by the activation of the classical complement system in addition to non-complement dependent inflammatory pathways. Complement fixation by…
2020 American Transplant Congress
The Protective Effect of Hypothermic Oxygenated Machine Perfusion (HOPE) Onresuscitating Steatotic Liver and its Underlying Mechanism
F. Lin¹, F. Zhen¹, X. Yan¹, L. Wenjin¹, Y. Qifa²
¹Zhongnan Hospital of Wuhan University, Wuhan, China, ²Zhongnan Hospital of Wuhan University/The Third Xiangya Hospital of Central South University, Wuhan/Changsha, China
*Purpose: To analyze the impact of steatotic livers with conventional cold storage (CS) and hypothermic oxygenated perfusion (HOPE) approaches, and further to investigate the rescue…
2020 American Transplant Congress
XIAP Enhances Xenoislet Survival: Novel Models to Evaluate Pretransplantation Gene Modifications
G. R. Devi¹, Z. Fitch¹, M. Song¹, M. Ribeiro¹, A. McGowan¹, X. Luo², B. H. Collins¹, A. D. Kirk¹
¹Department of Surgery, Duke Univesity School of Medicine, Durham, NC, ²Division of Nephrology, Duke Univesity School of Medicine, Durham, NC
*Purpose: Porcine islet xenotransplantation offers a reliable and near limitless supply of islets for the treatment of type 1 diabetes. Intraportal infusion of cells exposes…