Am J Transplant, Volume 20, Suppl 3 Archives - Page 209 of 223 - ATC Abstracts

2020 American Transplant Congress
Medical and Psychosocial Reasons for Deferral and Denial Following Kidney Transplant Evaluation at a VA Transplant Center
D. Katz¹, E. Siniff², M. L. Sanders³, P. Manay¹, P. Ten Eyck⁴
¹Surgery, University of Iowa, Iowa City, IA, ²Transplant, Iowa City Veterans Affairs Hospital, Iowa City, IA, ³Internal Medicine, University of Iowa, Iowa City, IA, ⁴ICTS, University of Iowa, Iowa City, IA
*Purpose: VA kidney transplant patients present challenges that may limit their listing opportunities in the private sector. We sought to study the medical and psychosocial…
2020 American Transplant Congress
Two-Year Post-Transplant eGFR as a Surrogate Outcome of Allograft Survival in Kidney Transplant Recipients
S. Yu, E. Lee, W. Zhang, D. Segev, J. Garonzik-Wang, A. Massie
Johns Hopkins, Baltimore, MD
*Purpose: Graft failure is a major cause of morbidity and mortality in kidney transplant recipients. However, trials aimed to assess the effect of interventions on…
2020 American Transplant Congress
Treg Protection of the Allograft Depends on Lymphotoxin Beta Receptor Expression in Lymphatic Endothelial Cells
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, C. Palusckievicz¹, T. Simon¹, M. Shirkey¹, R. Abdi², J. S. Bromberg¹
¹University of Maryland, Baltimore, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Regulatory T cell (Treg) migration to afferent lymphatics and lymph nodes (LN), and suppressive function, require Treg lymphotoxin alpha (LTα) to stimulate LT beta-receptor…
2020 American Transplant Congress
Belatacept-Based Regimens: Induction and Recipient Gender Influence Outcomes
N. Wilson¹, A. R. Shields², A. Wiseman³, A. L. Christianson¹, S. Tremblay¹, D. Kaufman⁴, J. P. Leone⁵, A. J. Matas⁶, P. West-Thielke⁷, R. R. Alloway¹, E. S. Woodle¹
¹U Cincinnati, Cincinnati, OH, ²The Christ Hospital, Cincinnati, OH, ³U Colorado, Denver, CO, ⁴U Wisconsin, Madison, WI, ⁵Tampa General, Tampa, FL, ⁶U Minnesota, Minneapolis, MN, ⁷U Illinois Chicago, Chicago, IL
*Purpose: Renal function and adverse event profiles in kidney transplant (KTx) patients under belatacept (BELA) based immunosuppression are significantly improved over calcineurin inhibitors, however BELA…
2020 American Transplant Congress
CD56^DimCD16^Bright NK Cells from Kidney Transplant Recipients with Antibody-Mediated Rejection Display Increased Proliferation, Self-Renewal, Pro-Inflammatory and Cytotoxic Profile
E. A. Bailly¹, K. Louis¹, C. Macedo¹, B. Ramaswami¹, M. Lucas¹, A. Zeevi¹, C. Lefaucheur², D. Metes¹
¹Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²INSERM UMR-S976. Endothelium, Inflammation & Alloreactivity, Université de Paris, France
*Purpose: Contribution of NK cells to antibody-mediated rejection (ABMR) injuries have recently been highlighted through transcriptomic analysis and immunohistochemistry of kidney and heart allograft biopsies.…
2020 American Transplant Congress
Trends in Liver Transplantation in Patients with Renal Failure Since Implementation of Simultaneous Liver-Kidney Allocation Policy
P. J. Altshuler, O. Shaheen, A. P. Shah, J. Glorioso, A. Frank, C. Ramirez, W. Maley, A. S. Bodzin
Department of Surgery, Thomas Jefferson University, Philadelphia, PA
*Purpose: To reduce potentially unnecessary kidney utilization, as of August 10, 2017 a new allocation policy was implemented restricting Simultaneous Liver Kidney (SLK) transplant to…
2020 American Transplant Congress
Prophylactic Biliary Intra-Operative Stents at Orthotopic Liver Transplantation (OLTx)
M. Aldamry
Mcgill University, Montreal, QC, Canada
*Purpose: Biliary complications can affect up to 40% of patients after orthotopic liver transplantation (OLTx). Endoscopic management has a high success rate but involves multiple…
2020 American Transplant Congress
The Case Against Race: Proportion of Minorities Does Not Explain Low DSA Donation Performance
R. Lynch, K. Ross, D. Goldberg
Emory University Hospital, Atlanta, GA
*Purpose: Chronic organ shortages result in unnecessary waitlist deaths, making improvements in donation an urgent problem in transplantation. Historically, barriers to donation have been noted…
2020 American Transplant Congress
An Optimized Integrative Model Using Urinary Chemokines for Noninvasive Diagnosis of Acute Allograft Rejection
C. Tinel¹, A. Devresse¹, A. Vermorel¹, D. Marx², S. Caillard², C. Legendre¹, M. Rabant³, D. Anglicheau¹
¹Nephrology and Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Nephrology and Kidney Transplantation, Strasbourg University Hospital, Strasbourg, France, ³Pathology, Necker Hospital, Paris, France
*Purpose: The aim of this study was to optimize the performance of urinary chemokines C-X-C motif ligand (CXCL) 9 and CXCL10 as noninvasive diagnostic markers…
2020 American Transplant Congress
Low HLA Class I Epitope Mismatch Associated with Improved Pancreas Graft Survival in Simultaneous Pancreas-Kidney Transplantation
J. M. Ladowski, M. Romine, D. Kloda, C. Young, J. Locke, V. Hauptfeld-Dolejsek, J. Houp
University of Alabama-Birmingham, Birmingham, AL
*Purpose: Antibody-mediated rejection remains the principal cause of allotransplant graft failure. Human leukocyte antigen (HLA) matching between donor and recipients significantly reduces the risk of…