Am J Transplant, Volume 20, Suppl 3 Archives - Page 207 of 223 - ATC Abstracts

2020 American Transplant Congress
Unique Genomic & Proteomic Profile of Liver Mesenchymal Stromal Cells is Associated with Their Superior Immunomodulatory Properties
F. Yigitbilek, W. D. Park, N. Abrol, M. D. Stegall, T. Taner
Transplant Center, Mayo Clinic, Rochester, MN
*Purpose: Investigating mechanisms of liver allografts’ relative tolerance, we recently reported that liver mesenchymal stromal cells (L-MSC) are superior in their capacity to inhibit alloimmune…
2020 American Transplant Congress
Characterization of Laminin Alpha 4 Conditional Knockout Mice: Model for Immune Stimulation
M. W. Shirkey, L. Li, W. Piao, Y. Xiong, V. Saxena, T. Zhang, C. Paluskievicz, J. Bromberg
U. Maryland, Baltimore, MD
*Purpose: Lymph node (LN) stromal laminin α4 (Lama4) and α5 (Lama5) are associated with tolerance and immunity, respectively. We created a Lama4 conditional knockout (KO)…
2020 American Transplant Congress
Donor and Recipient Sex Affect Transplant Outcomes in an Age-Specific Fashion
R. Maenosono¹, Y. Nian¹, J. Iske¹, Y. Liu¹, H. Azuma², E. Milford³, S. G. Tullius¹
¹Division of Transplant Surgery, Brigham and Women's Hospital, Boston, MA, ²Urology, Osaka Medical College, Osaka, Japan, ³Renal Division, Brigham and Women's Hospital, Boston, MA
*Purpose: Donor and recipient sex impact transplant outcomes. The biology of sex-specific alloimmune responses has not been studied in detail.*Methods: Using clinical data from more…
2020 American Transplant Congress
Exosomes Derived from MSC Ameliorate Renal Ischemic-Reperfusion Injury Through Inhibiting Inflammation and Cell Apoptosis
Y. Jia, M. Xu, T. Zhu
Shanghai Key Laboratory of Organ Transplantation, Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: Investigate the underlying mechanism of mesenchymal stem cells (MSCs) on protection of renal ischemia reperfusion injury (IRI) .*Methods: Exosomes originated from MSCs (MSC-ex) were…
2020 American Transplant Congress
The Financial Concerns of Non-Directed (Altruistic) Living Kidney Donors – How Can We Improve the Donation Process?
A. Maghen¹, G. Mendoza¹, G. B. Vargas¹, S. E. Connor¹, S. Nassiri¹, L. Kwan¹, E. L. Wood¹, J. Lalezari¹, S. Friedman¹, A. D. Waterman², S. George³, S. L. Maliski⁴, J. L. Veale¹
¹Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ²Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, ³Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, CA, ⁴Office of the Dean, University of Kansas Medical Center School of Nursing, Kansas City, KS
*Purpose: The recent increase in non-directed (altruistic) kidney donors (NDDs) in the United States (U.S.) suggests their potential to help reduce the overburdened kidney transplant…
2020 American Transplant Congress
Thymoglobulin Induction in Kidney Transplant Recipients: A Single Center Experience Comparing 3 Mg/kg vs 5 Mg/kg Cumulative Dosing
K. Progar¹, S. January¹, N. Nesselhauf¹, J. Hagopian¹, A. Malone²
¹Transplant, Barnes-Jewish Hospital, St. Louis, MO, ²Transplant Nephrology, Washington University, St. Louis, MO
*Purpose: Beginning in 2016, our center implemented a protocol change to thymoglobulin (r-ATG) induction dosing in kidney transplant recipients at low rejection risk from 5…
2020 American Transplant Congress
The Effect of African American Race on Morbidity for Donors Undergoing Living Kidney Donation: A Single Center Study
D. R. White, F. Desrosiers, S. Sultan, R. Craig-Schapiro, J. del Pizzo, S. Kapur, A. Watkins
Kidney and Pancreas Transplantation, Weill Cornell Medicine, New York, NY
*Purpose: To assess perioperative complication rates in African-Americans (AA) undergoing living donor nephrectomy in a large, single center program in the northeast.*Methods: We performed a…
2020 American Transplant Congress
Patient and Kidney Allograft Outcomes in Septuagenarians – A Single Center Experience
G. Katz-Greenberg, A. Yadav, M. P. Martinez-Cantarin, P. Singh
Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: Based on Scientific Registry of Transplant Recipients reporting, the proportion of patients 65 years or older on the kidney transplant (KT) waiting list has…
2020 American Transplant Congress
Medication Knowledge Improves in Adolescent Kidney Transplant Patients with in Clinic Pharmacy Education
C. G. Peterson¹, E. Benefield², C. Heyrend²
¹Pediatric Nephrology, University of Utah, Salt Lake City, UT, ²Transplant Pharmacy, Primary Children's Hospital, Salt Lake City, UT
*Purpose: Successful transition of adolescent and young adult transplant recipients to adult-centered care remains challenging for transplant centers. This transition is associated with graft loss…
2020 American Transplant Congress
Validation of Prognostic Index for Allograft Outcome in Kidney Transplant Recipients with Transplant Glomerulopathy
M. Talwar¹, V. Balaraman¹, A. Bhalla¹, O. Cseprekal², M. Yazawa¹, P. S. Podila³, A. Azhar¹, L. N. Cossey⁴, J. D. Eason¹, M. Z. Molnar¹
¹James D. Eason Transplant Institute, Methodist University Hospital, Memphis, TN, ²Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary, ³Faith & Health Division, Methodist Le Bonheur Healthcare, Memphis, TN, ⁴Arkanalabs, Little Rock, AR
*Purpose: Kidney transplant recipients with Transplant Glomerulopathy (TG) have very poor allograft survival compared to those without TG. The objective of this research was to…