ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Frequency and Main Diagnoses of Hospitalizations in Patients after Kidney Transplantation

    W. Duettmann-Rehnolt, P. Glander, P. Bach, F. Halleck, V. Graf, L. Lehner, M. Duerr, M. Mayrdorfer, K. Budde, M. Naik

    Nephrology, Charité-Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Kidney transplant recipients (KTR) suffer many complications and are hospitalized frequently. Specific reasons for hospital admission with detailed information are scarce.*Methods: We retrieved data…
  • 2020 American Transplant Congress

    Access to and Survival Benefit of Kidney Transplantation in Patients with Sickle Cell Disease-Associated End-Stage Renal Disease in the United States

    S. Bae, M. Johnson, A. Massie, X. Luo, C. Haywood Jr., S. Lanzkron, M. Grams, D. Segev, T. Purnell

    Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Patients with end-stage renal disease due to sickle cell disease (SCD-ESRD) have high mortality, which might be reduced by kidney transplantation (KT). However, whether…
  • 2020 American Transplant Congress

    Challenges in Examining Transplant Outcomes in Patients with Fontan-Associated Liver Disease

    R. T. Fischer1, M. H. Kim2, A. Nguyen3, S. R. Kumar3, J. Bucuvalas4, E. F. Glynn1, M. A. Hoffman1, J. Emamaullee3

    1Children's Mercy Hospital, Kansas City, MO, 2Children's Hospital-Los Angeles, Los Angeles, CA, 3University of Southern California, Los Angeles, CA, 4Mount Sinai Kravis Children's Hospital, New York, NY

    *Purpose: The Fontan procedure has allowed patients born with single ventricle physiology to survive into adulthood. It is projected that the mean age of Fontan…
  • 2020 American Transplant Congress

    Association between Homograft Tissue Exposure and Pre-Sensitization Prior to Heart Transplant in Patients with Congenital Heart Disease

    D. J. Donovan1, M. E. Richmond2, E. A. Bacha3, L. J. Addonizio2, W. A. Zuckerman2

    1Pediatrics, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, 2Pediatric Cardiology, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, 3Pediatric Cardiac Surgery, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY

    *Purpose: Surgical repair for patients with congenital heart disease (CHD) often incorporates homograft tissue or other biologic material, which can lead to pre-sensitization. We sought…
  • 2020 American Transplant Congress

    Peri-Operative Extracorporeal Photopheresis in High Risk Patients after Heart Transplantation

    A. Zuckermann1, J. Gökler1, N. Worel2, P. Angleitner1, E. Ceran1, E. Ceran1, N. Neuber1, P. Kaiser1, G. Laufer1, A. Aliabadi-Zuckermann1

    1Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria, 2Department of Transfusion Medicine, Medical University of Vienna, Vienna, Austria

    *Purpose: Extracorporeal photopheresis (ECP) is an established therapy for treatment of heart transplant rejection and is also applied for rejection prevention in the perioperative setting…
  • 2020 American Transplant Congress

    Outcomes of a Pre-Transplant Desensitization Protocol with Carfilzomib, Plasmapheresis, and IVIG for Broadly Sensitized Lung Transplant Candidates: A Case Series

    S. Fredrick1, C. Iasella2, C. Moore1, M. Mangiola3, Q. Xu3, C. Ensor4, D. Riciutti2, C. LaFratte2, P. Sanchez3, M. Morrell3, J. McDyer3, A. Zeevi3

    1Department of Pharmacy, UPMC Presbyterian, Pittsburgh, PA, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA, 3University of Pittsburgh School of Medicine, Pittsburgh, PA, 4Department of Pharmacy, AdventHealth, Orlando, FL

    *Purpose: The presence of anti-human leukocyte antigen (HLA) antibodies in lung transplant candidates leads to increased wait list times and antibody-mediated rejection (AMR) post-transplant. We…
  • 2020 American Transplant Congress

    Teduglutide Therapy in Real World Setting is Efficacious in Reducing Complications in Short Bowel Syndrome

    T. Ashraf1, V. Mendiratta2, M. Abu Ghanimeh2, H. Abdulla1, S. Nagai3, N. Beltran3, S. Jafri2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 3Transplant Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: Teduglutide, a GLP-2 analogue, increases portal and intestinal blood flow thereby increasing absorption of fluid and nutrients. We evaluated outcomes of Teduglutide therapy for…
  • 2020 American Transplant Congress

    Combining New Biomarkers: Donor Derived Cell Free DNA (dd-cfDNA) and Transcriptomics Impacts Rejection Diagnosis, Treatment and Follow Up

    S. Anand, L. Dong, D. Miller, I. Lloyd, D. Morris, T. Srinivas

    Intermountain Medical Center, Murray, UT

    *Purpose: Transcriptomics (Tr) is an emerging adjunct to traditional histological diagnosis (HDx) for kidney allograft rejection (KAR). We describe our experience of using Tr and…
  • 2020 American Transplant Congress

    Evolution of Molecular MMDx Scores after Kidney Transplantationin Different Donor Categories

    P. Hruba1, K. S. Madill-Thomsen2, M. Mackova2, J. Maluskova3, E. Honsova3, J. Slatinska4, P. F. Halloran2, O. Viklicky4

    1Transplant Laboratory, IKEM, Prague, Czech Republic, 2ATAGC, University of Alberta, Edmonton, AB, Canada, 3Department of Pathology, IKEM, Prague, Czech Republic, 4Department of Nephrology, IKEM, Prague, Czech Republic

    *Purpose: The outcome of kidney transplantation is highly affected by donor category. Little is known about molecular processes which may underline this phenomenon.*Methods: Using Molecular…
  • 2020 American Transplant Congress

    Graft Perfusion with an Hsp90 Inhibitor Prolongs Graft Survival in Murine Heart Transplantation by Modulating Expression of Cyclin-Dependent Kinases and the Senolytic Effect

    T. Tanaka, T. Maehana, N. Masumori

    Department of Urology, Sapporo Medical University, Sapporo, Japan

    *Purpose: We have previously demonstrated that administration of alvespimycin, a heat shock protein 90 (HSP90) inhibitor, prolongs the allograft survival in murine skin and heart…
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