Am J Transplant, Volume 20, Suppl 3 Archives - Page 205 of 223 - ATC Abstracts

2020 American Transplant Congress
Intestinal Retransplantation: Survival Outcomes Similar to Primary Transplantation
C. Beyersdorf, L. Vargas, D. Mercer, W. Grant, A. Langnas, S. Merani
University of Nebraska Medical Center, Omaha, NE
*Purpose: Isolated and multivisceral intestinal transplantation is indicated for patients with life threatening complications of intestinal failure. Intestinal retransplantation has been performed in select intestinal…
2020 American Transplant Congress
Selective Dual Co-Stimulatory Blockade of CD28/CD80-86 and PD1-PL2 with a Novel Recombinant Bi-Specific Fusion Protein (Hybri-2) Promotes Successful Humoral Desensitization in a Stringent Sensitized Rat Model
A. Torija, E. Crespo, M. Jarque, N. Bolaños, M. Meneghini, A. Favà, J. Torras, J. Grinyo, O. Bestard
Kidney Transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain
*Purpose: Humoral Alloimmune memory is a main barrier for successful kidney transplantation and is orchestrated by a compartmentalized cellular immune response driven by bone-marrow LLPCs…
2020 American Transplant Congress
Feasibility and Long Term Safety of T Regulatory Cell Therapy in Kidney Transplantation
P. N. Harden¹, D. Game², J. Van der Net¹, F. Issa³, W. Petchey¹, M. Brook¹, P. Friend¹, R. Hilton⁴, G. Lombardi⁵, K. Wood³
¹Kidney Transplantation, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, ²Kidney Transplantation, Guys and St Thomas's Hospital, London, United Kingdom, ³Transplant Immunology Research Group, Oxford University, Oxford, United Kingdom, ⁴Kidney Transplantation, Guys and St Thomas's Hospital, Oxford, United Kingdom, ⁵Transplant Immunology Group, Kings Healthcare Partners, London, United Kingdom
*Purpose: A sequential clinical trial of autologous polyclonal T regulatory cellular therapy compared with a standardised reference cohort of live donor kidney transplant recipients. The…
2020 American Transplant Congress
Protocolized Exercise Improves Frailty Parameters and Lower Extremity Impairment: A Promising Prehabilitation Strategy for Kidney Transplant Candidates
E. C. Lorenz, L. J. Hickson, R. Weatherly, K. Thompson, H. Walker, J. Rasmussen, T. Stewart, J. Garrett, C. C. Kennedy
Mayo Clinic, Rochester, MN
*Purpose: Frailty and lower extremity (LE) impairment are risk factors for numerous adverse outcomes in kidney transplant (KT) candidates, including decreased rates of transplantation, increased…
2020 American Transplant Congress
Living Kidney Donation is Associated with Accelerated Podocyte Loss Early after Donation
A. S. Naik, D. Le, S. Wang, M. Chowdhury, M. D. Doshi, R. Wiggins
University of Michigan, Ann Arbor, MI
*Purpose: Living kidney donation (LKD) is associated with increased long-term risk of CKD/ESRD. Post donation DM/HTN are associated with this increased risk. However, the remaining…
2020 American Transplant Congress
Liver Retransplantation (reLT) in the Modern Post-MELD, Post-DAA Era
B. Shi, C. Freise, D. Brandman
School of Medicine, UCSF, San Francisco, CA
*Purpose: Liver retransplantation (reLT) is responsible for a small proportion of all liver transplants (LT), but outcomes are much worse than primary LT. Hepatitis C…
2020 American Transplant Congress
A Survey of Lung Transplant Recipient Attitudes and Beliefs on Accepting an Organ That Was Positive for Hepatitis C Virus
S. S. Humar¹, N. Pinzon¹, M. Cypel¹, S. Abbey²
¹University Health Network, Transplant Center, Toronto, ON, Canada, ²University Health Network, Center for Mental Health, Toronto, ON, Canada
*Purpose: Recent data show that organs from donors who are HCV positive (+ve) can be safely transplanted into HCV negative recipients. We conducted a survey…
2020 American Transplant Congress
Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers
J. Kim, C. Lee, W. Chapman
Surgery, Washington University St. Louis, St. Louis, MO
*Purpose: Aged livers are far more susceptible to ischemia/reperfusion (I/R) injury than young livers. No therapeutic strategies are available to reduce I/R injury in elderly…
2020 American Transplant Congress
Role of Innate Allorecognition Pathways in Mouse Kidney and Heart Allograft Rejection
D. Zhao¹, H. Dai¹, K. Abou-Daya¹, R. Tieu¹, A. Williams¹, M. Oberbarnscheidt¹, X. Li², F. Lakkis¹
¹Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²Houston Methodist Hospital Immunobiology & Transplant Science Center, Houston, TX
*Purpose: Paired immunoglobulin-like receptors (PIR) and CD47 are molecules expressed on host myeloid cells. They recognize donor polymorphic MHC and signal regulatory protein alpha (SIRPα),…
2020 American Transplant Congress
An Evaluation of Deceased Donor Eligibility and US Organ Donation Rates
L. DeRoos¹, Y. Zhou², W. Marrero¹, M. Lavieri¹, D. Hutton³, N. Parikh⁴
¹Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, ²Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, ³School of Public Health, University of Michigan, Ann Arbor, MI, ⁴Internal Medicine, University of Michigan, Ann Arbor, MI
*Purpose: Organ Procurement Organization (OPO) performance assessment is essential for identifying best practices and improvement opportunities. We aimed to evaluate OPO performance using the following…