Am J Transplant, Volume 20, Suppl 3 Archives - Page 2 of 223 - ATC Abstracts

2020 American Transplant Congress
Testing Deceased Organ Donors for Infections: An Organ Procurement Organization (OPO) Survey
N. M. Theodoropoulos¹, P. Chin-Hong², M. Greenwald³, M. G. Ison⁴
¹University of Massachusetts Medical School, Worcester, MA, ²UCSF, San Francisco, CA, ³Uniformed Services University School of Medicine, Bethesda, MD, ⁴Northwestern University, Chicago, IL
*Purpose: We surveyed the 58 U.S. OPOs to update our knowledge about the current methods of infectious disease testing in deceased organ donors.*Methods: An IRB…
2020 American Transplant Congress
Evaluation of the Discrimination of 13 Mortality Risk Scores after Heart Transplantation in a Contemporary UNOS Cohort
G. Coutance, J. Patel, E. Kransdorf, R. Levine, E. Passano, J. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Multiple pre-transplant scores aimed at stratifying the risk of death or allograft loss after heart transplantation have been developed over time but their use…
2020 American Transplant Congress
Survival of ESRD Patients with an EPTS > 90% Listed for Kidney Transplant
M. S. Sampaio¹, E. Lum¹, P. Homkrailas¹, G. Danovitch¹, H. Gritsch², S. Bunnapradist¹
¹UCLA - Division of Nephrology, Los Angeles, CA, ²UCLA - Division of Urology, Los Angeles, CA
*Purpose: Mortality on the kidney transplant waitlist is high especially in candidates with a high Estimated Post Transplant Survival (EPTS) score. We examined outcomes of…
2020 American Transplant Congress
Imaging OX40+Alloreactive T Cells Provides Early Warning of Organ Transplant Rejection
T. Hirai¹, A. Mayer², T. W. Nobashi², Z. Xiao², T. Udagawa³, K. Seo⁴, F. Simonetta⁵, J. Baker⁵, A. Cheng³, S. S. Gambhir², R. S. Negrin⁵
¹Department of Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Department of Radiology, Stanford University, Stanford, CA, ³Department of Otolaryngology-Head and Neck Surgery, Stanford University, Stanford, CA, ⁴Division of Cardiovascular Medicine, Stanford University, Stanford, CA, ⁵Division of Blood and Marrow Transplantation, Stanford University, Stanford, CA
*Purpose: Diagnosis of organ transplant rejection relies upon biopsy approaches to confirm alloreactive T cell infiltration in the graft. Immuno positron emission tomography (immunoPET) utilizing…
2020 American Transplant Congress
Virtual XM Adversely Affects Access for Highly Sensitized African Americans Awaiting Renal Transplantation
P. T. Jindra¹, B. V. Murthy¹, C. Van Buren²
¹Surgery, Baylor College of Medicine, Houston, TX, ²Surgery, UT Medical School, Houston, TX
*Purpose: Recent UNOS policy proposals have changed kidney allocation from local Designated Service Areas (DSA) to geographic distribution areas of varying widths. Since crossmatch of…
2020 American Transplant Congress
Adjuvant Immunotherapy for Liver Transplant Recipients with Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells
M. Ohira¹, R. Hotta¹, Y. Imaoka¹, K. Sato¹, N. Tanimine¹, H. Tahara¹, K. Ide¹, T. Kobayashi¹, Y. Tanaka¹, A. Tzakis², S. Nishida², H. Ohdan¹
¹Hiroshima University, Hiroshima, Japan, ²University of Miami, Miami, FL
*Purpose: Development of an effective adjuvant therapy to prevent HCC recurrence after liver transplantation (LT) is an important medical requirement. Immunosuppressive regimens currently used after…
2020 American Transplant Congress
Re-Examining Sex-Based Differences in Liver Transplant Outcomes for HCV Cirrhosis
D. Yoeli¹, R. Choudhury¹, H. Moore¹, A. Sauaia¹, M. Simpson², E. Pomfret¹, T. Nydam¹
¹Transplant Surgery, University of Colorado, Aurora, CO, ²Transplant Surgery, Lahey Hospital and Medical Center, Burlington, MA
*Purpose: Previous studies have demonstrated that female liver transplant recipients with hepatitis C (HCV) are at increased risk for graft failure due to disease recurrence…
2020 American Transplant Congress
Pharmacy Led Initiatives for Treatment of Transplant Recipients of Hepatitis C Viremic Donors in a High Volume Transplant Center
H. Berry, J. Byrns, L. Crona, T. Capes, J. M. Steinbrink, E. K. Maziarz, C. R. Wolfe
Duke University Medical Center, Durham, NC
*Purpose: We describe a multidisciplinary workflow for initiation of hepatitis C virus (HCV) direct-acting antiviral (DAA) therapies post-transplant in the outpatient setting of a high…
2020 American Transplant Congress
Effects of Donor Specific Antibodies in Intestinal/Multivisceral Transplant Recipients
K. Klein¹, M. Keck², E. Langewisch², S. Merani², M. Leick²
¹University Health System, San Antonio, TX, ²Nebraska Medicine, Omaha, NE
*Purpose: Evaluate the effects of donor specific antibodies (DSAs) on outcomes in post-intestinal/multivisceral (MV) transplant patients and describe the presentation of DSAs post-transplant.*Methods: This single-center…
2020 American Transplant Congress
Donor-Derived DCREG Infusion Prolongs Kidney Allograft Survival in Rhesus Monkeys Treated with Co-Stimulation Blockade and Calcineurin Inhibition
Y. Wang, S. Kazuki, L. Lu, A. Zahorchak, H. Dai, A. Ganoza, M. Wijkstrom, A. Humar, M. Ezzelarab, A. Thomson
Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: We have shown previously that pre-transplantation (Tx) infusion of donor-derived regulatory dendritic cells (DCreg) safely prolongs MHC-mismatched renal allograft survival and regulates donor-reactive T…