ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease after Kidney Transplantation

    M. Raynaud1, O. Aubert1, P. Reese2, M. Naesens3, D. Glotz1, C. Legendre1, S. Jordan4, M. Stegall5, D. Segev6, C. Lefaucheur1, A. Loupy, On behalf of the study NCT034740031

    1Paris Transplant Group, Paris, France, 2University of Pennsylvania, Philadelphia, PA, 3Department of Transplantation, Leuven, Belgium, 4Cedars Sinai, Los Angeles, CA, 5Mayo Clinic, Rochester, MN, 6Johns Hopkins, Baltimore, MD

    *Purpose: Although the current gold standard of monitoring kidney transplant function relies on glomerular filtration rate (GFR) assessment, little is known about GFR trajectories after…
  • 2020 American Transplant Congress

    A Simple HLA Class II Matching Strategy for the Prediction of De Novo Donor-Specific HLA Antibodies

    L. G. Hidalgo1, I. A. Martinez Juarez2, L. Morales-Buenrostro3, S. Shojai4, P. Campbell4

    1Surgery, University of Wisconsin - Madison, Madison, WI, 2Nephrology, Hospital Angeles Pedregal, Mexico City, Mexico, 3Nephrology, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico, 4Medicine, University of Alberta, Edmonton, AB, Canada

    *Purpose: In kidney transplantation, degree of HLA Class II mismatch (MM) between donor and recipient drives the risk to develop de novo DSA (dnDSA). New…
  • 2020 American Transplant Congress

    Safety and Effectiveness of Early Initiation of SGLT2 Inhibitors in Diabetic Kidney Transplant Recipients

    C. Song1, R. Winstead1, A. Brown1, M. Demehin1, I. Yakubu1, I. Moinuddin2, G. Gupta2

    1Pharmacy, Virginia Commonwealth University Health, Richmond, VA, 2Virginia Commonwealth University Health, Richmond, VA

    *Purpose: Metabolic complications such as post-transplant diabetes (PTDM) are quickly becoming the leading causes of death in kidney transplant (KT) recipients. The use of Sodium…
  • 2020 American Transplant Congress

    Pumping in Pediatric Kidney Transplantation—Does it Matter?

    M. MacConmara, J. Gattineni, D. Desai, P. Vagefi, C. S. Hwang

    UT Southwestern, Dallas, TX

    *Purpose: Pulsatile perfusion of deceased donor kidneys is commonly practiced in adult kidney transplantation. We examined the practice of pulsatile perfusion in pediatric patients undergoing…
  • 2020 American Transplant Congress

    De Novo NAFLD Post-Liver Transplant is Defined by Altered Lipid Metabolism and Mitochondrial Dysfunction

    M. Bhat1, E. Pasini1, M. Angeli1, J. Allard2, A. Humar1

    1Multi-Organ Transplant, UHN, Toronto, ON, Canada, 2Division of Gastroenterology and Hepatology, UHN, Toronto, ON, Canada

    *Purpose: De Novo Non-alcoholic Fatty Liver Disease (NAFLD) affects up to 35% of liver transplant (LT) recipients transplanted for non-NAFLD indications. Non-alcoholic steatohepatitis (NASH), the…
  • 2020 American Transplant Congress

    Outcomes of Kidney Transplant Patients Evaluated, Listed and Managed Using A Distant Transplant Outreach Care Model (DTrOM)

    M. Mujtaba, M. Kueht, S. Hussain, A. Rizvi, S. Shah, R. Kulkarni, S. N. Merwat, A. Gamilla-Crudo, K. Gugliuzza, J. Fair

    UTMB, Galveston, TX

    *Purpose: All advanced kidney disease and post-transplant patients are not always fortunate enough to be living close to a transplant care center. To this end,…
  • 2020 American Transplant Congress

    Outcome Implications of Prescription Opioid and Benzodiazepine in Lung Transplant Patients: Analysis of Linked Registry and Pharmacy Claims Data

    K. Lentine1, L. Myaskovsky2, H. Bruschwein3, M. Dew4, Z. Zhang1, M. McAdams Demarco5, D. Segev5, D. Axelrod6, G. Hess7, B. Kasiske8, J. Snyder8, M. Schnitzler9

    1Department of Medicine, Saint Louis University, Saint Louis, MO, 2Univ of New Mexico, Albuquerque, NM, 3Univ of Virginia, Charlottesville, VA, 4Univ of Pittsburgh, Pittsburgh, PA, 5Johns Hopkins, Baltimore, MD, 6Univ of Iowa, Iowa City, IA, 7Drexel University, Philadelphia, PA, 8SRTR, Minneapolis, MN, 9Saint Louis University, Saint Louis, MO

    *Purpose: To investigate the frequency, correlates, and outcomes associated with prescription opioid and benzodiazepine use before and after lung transplant (LuTx).*Methods: We examined a linkage…
  • 2020 American Transplant Congress

    Identification of the dnDSA Inducing HLA Mismatches Across Multiple Renal Transplant Centers: A 3-Year Longitudinal Analysis of >11,000 HLA Mismatches in 2271 Patients

    J. M. Brennan1, M. D. Stegall2, C. A. Schinstock2, R. L. Heilman3, L. M. Rebellato4, M. D. Samaniego-Picota5, D. Lesser4, M. J. Ghandi2, J. L. Beaumont1, M. J. Everly1

    1Terasaki Research Institute, Los Angeles, CA, 2Mayo Clinic, Rochester, MN, 3Mayo Clinic, Phoenix, AZ, 4East Carolina University, Greenville, NC, 5Henry Ford Transplant Institute, Detroit, MI

    *Purpose: The presence of a mismatch (MM) between donor and recipient HLA does not always lead to the patient developing a de novo donor-specific anti-HLA…
  • 2020 American Transplant Congress

    Prospective Donor-Specific CellUlar Alloresponse Assessment for Immunosuppression MinImization in De Novo Renal Transplantation: Results of a Randomized Controlled Biomarker-Guided Trial

    O. Bestard1, P. Reinke2, F. Bemelman3, O. Viklicky4, M. Koch5, M. Giral6, J. Ruiz7, B. Banas8, E. Crespo1, M. Meneghini1, H. Volk9, J. Grinyo1

    1Kidney transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, 2Kidney transplantation Unit, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Kidney transplantation Unit, Amsterdam Medical Centre, Amsterdam, Netherlands, 4Nephrology department, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 5Department of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 6Nephrology, Kidney transplantation Unit, Université de Nantes, Nantes, France, 7Nephrology, Hospital Marques de Valdecilla, Santander, Spain, 8Kidney transplantation Unit, University Hospital Regensburg, Regensburg, Germany, 9Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Early immunosuppression minimization is associated with higher rates of BPAR. Preformed donor-specific T-cell alloreactivity (DST) assessed with an IFN-γ ELISPOT assay has shown to…
  • 2020 American Transplant Congress

    Characteristics of Anonymous Living Donors and Their Recipients. Appropriate Use of a Rare and Valuable Gift

    A. Sharfuddin, M. Panezai, M. Yaqub, D. Mishler, O. Adebiyi, T. Taber

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Anonymous Living Donors are a special select set of donors. As there continues to be advances in Paired Donation, we review the trends and…
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