ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Metformin Improves Biomarkers of Calcineurin Inhibitor Related Nephrotoxicity

    M. R. Fernando, K. Taylor, S. Herath, A. Au, J. Erlich, Z. Endre

    Department of Nephrology, Prince of Wales Hospital, Randwick, Australia

    *Purpose: Calcineurin Inhibitors (CNIs) prevent transplant rejection but cause significant nephrotoxicity. Biomarkers of CNI nephrotoxicity could help drug dosing and improve long-term graft outcomes. As…
  • 2020 American Transplant Congress

    Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication During Cardiac Allograft Rejection in the Mouse Heart Transplantation

    Y. Tang, X. Shi, X. He

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    *Purpose: Allograft rejection is still the leading causes of the graft loss, especially long-term outcome. Single-cell genomics techniques are revolutionizing our ability to comprehensively characterize…
  • 2020 American Transplant Congress

    Changes in Gut Microbiota and Acute Rejection after Kidney Transplantation

    H. Cho1, J. Kim2, H. Kim2, J. Park3, M. Kwak4, B. Kim4, D. Kim2, J. Lee5, B. Kim6, H. Lee2

    1Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea, Republic of, 2Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 3Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea, Republic of, 4ChunLab Inc. Seoul National University, Seoul, Korea, Republic of, 5Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of, 6Department of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Korea, Republic of

    *Purpose: Kidney transplantation (KT) is the best treatment for end-stage renal disease. Although rejection is a normal immune response of the body to a foreign…
  • 2020 American Transplant Congress

    Mitochondrial Metabolism is Enriched Following Normothermic Ex-Vivo Kidney Perfusion of Grafts Procured Following Cardiac Death

    P. Urbanellis1, C. McEvoy1, L. Mazilescu1, S. Ganesh1, R. John1, I. Mucsi1, A. Ghanekar1, D. Bagli2, A. Konvalinka1, L. Robinson2, M. Selzner1

    1University Health Network, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) preservation has demonstrated superior graft outcomes for kidneys procured following donation-after-cardiac death (DCD) over static cold storage (SCS). To…
  • 2020 American Transplant Congress

    Outcomes of Kidney Donors with Impaired Fasting Glucose and Diabetes

    S. Hebert, D. T. Nguyen, E. A. Graviss, H. E. Adrogue, A. Gaber, A. Matas, H. Ibrahim

    Houston Methodist Hospital, Houston, TX

    *Purpose: Many kidney donor candidates with impaired fasting glucose (IFG) and all candidates with diabetes (DM) are excluded from donation. The diagnostic thresholds for IFG…
  • 2020 American Transplant Congress

    Geographic Variation in Listing for Kidney Transplantation: A State-Level Assessment of Access among Patients with End-Stage Renal Disease in the United States

    M. N. Mustian, H. Qu, D. Anderson, P. A. MacLennan, R. D. Reed, C. Kale, B. Orandi, B. A. Shelton, V. Kumar, M. Hanaway, J. E. Locke

    University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Barriers to deceased donor kidney transplantation (DDKT) exist, including referral for transplant and waitlist addition, which may vary regionally. The objective of this study…
  • 2020 American Transplant Congress

    Higher Body Mass Index Before Living Kidney Donation Can Increase Wound Infection after Hand-Assisted Laparoscopic Living Donor Nephrectomies

    X. Benavides, M. Merzkani, R. T. Rogers, E. K. Tan, S. Thirunavukkarasu, B. H. Smith, A. D. Rule, M. Prieto, J. K. Heimbach, T. Taner, G. K. Chow, P. G. Dean, M. D. Stegall

    Kidney Transplant, Mayo Clinic, Rochester, MN

    *Purpose: According to the CDC (2015-2016), 71.6% of the adult population in the United States has a BMI equal or higher than 25kg/m2, and the…
  • 2020 American Transplant Congress

    Calcium Level-Dependence of the Adverse Effect of Tertiary Hyperparathyroidism on Graft Survival in Renal Transplant Recipients

    M. Okada, T. Tomosugi, T. Hiramitsu, K. Futamura, A. Kanda, N. Goto, S. Narumi, T. Ichimori, Y. Watarai

    Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan

    *Purpose: Tertiary hyperparathyroidism (THPT) is a condition in which hyperparathyroidism persists after renal transplantation (RTx), and is a frequent complication. The aim of this retrospective…
  • 2020 American Transplant Congress

    Risk Factors of Focal Segmental Glomerulosclerosis Recurrence in Pediatric Kidney Transplant Recipients : Single Center Experience

    C. T. Chung, H. Ko, H. Mo, H. Kim, A. Han, S. Min, J. Ha

    Seoul National University, College of Medicine, Seoul, Korea, Republic of

    *Purpose: Focal segmental glomerulosclerosis (FSGS) is one of the most common causes of end stage renal diseases (ESRD) in children. Many pediatric patients diagnosed with…
  • 2020 American Transplant Congress

    Reduced Dose of Mycophenolate Mofetil as Well as Preformed DSA Are Risk Factors Associated with the Development of Chronic Active Antibody Mediated Rejection after Kidney Transplantation: A Retrospective Case Control Study

    K. Shinoda1, H. Oguchi1, K. Nishikawa1, T. Yonekura1, M. Muramatsu1, T. Kawamura1, Y. Hamasaki1, T. Mikami2, K. Sakai1, S. Shishido1

    1Toho University Faculty of Medicine, Tokyo, Japan, 2Pathology, Toho University Faculty of Medicine, Tokyo, Japan

    *Purpose: The purpose of this study is to explore the risk factors associated with the development of chronic active antibody mediated rejection (CAAMR) after the…
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