Am J Transplant, Volume 20, Suppl 3 Archives - Page 18 of 223 - ATC Abstracts

2020 American Transplant Congress
Survey on Solid Organ Pancreas Transplantation in the United States: Plenty of Insulin, Short on Procedures!
R. F. Parsons¹, T. Alhamad², K. L. Lentine³, A. Basu¹, K. J. Woodside⁴, G. Romeo⁵, C. Klein⁶, M. Pavlakis⁷, J. Friedewald⁸, D. Dadhania⁹, M. Cooper¹⁰
¹Emory Univ, Atlanta, GA, ²Washington Univ, St. Louis, MO, ³St. Louis Univ, St. Louis, MO, ⁴Univ Michigan, Ann Arbor, MI, ⁵Harvard, Boston, MA, ⁶Piedmont, Atlanta, GA, ⁷BIDMC, Boston, MA, ⁸Northwestern, Chicago, IL, ⁹Weill Cornell Medical College – NYP, New York, NY, ¹⁰Georgetown Univ, Washington, DC
*Purpose: For 15 years pancreas transplantation (PT) numbers have paradoxically declined. We sought to understand the drop in all types of PT and to find…
2020 American Transplant Congress
Belatacept Suppresses the B-Cell Alloresponse in the Lower Range of Therapeutic Trough Concentrations
C. Ashokkumar¹, R. Townsend², M. Roberts², T. Lehman², B. Gavin², B. Spishock¹, R. Sindhi¹
¹Plexision, Pittsburgh, PA, ²Bristol-Myers-Squibb, Princeton, NJ
*Purpose: Background: Kidney recipients treated with the T-cell costimulation blocker, belatacept, experience a higher incidence of acute cellular rejection (ACR) and lower incidence of donor-specific…
2020 American Transplant Congress
Transcriptome-Based Study of Tim-1- B Cells and Tim-1+ Regulatory B Cells
Q. Fu, K. Lee, C. G. Rickert, G. Huai, K. Deng, N. Feeney, N. Tanimine, A. G. Cuenca, S. Deng, J. F. Markmann
Center for Transplant Science, MGH, Boston, MA
*Purpose: Tim-1 signaling has an important role in maintaining the function of Regulatory B cells. Our previous study suggested Tim-1+ Bregs can prolong the survival…
2020 American Transplant Congress
Optimal Recipient Selection and Surgical Complications in Dual Kidney Transplantation
S. Patel¹, S. Chang², R. Sussman³, R. Plews¹, R. Lopez-Soler⁴, D. Conti¹
¹Kidney and Pancreas Transplantation, Albany Medical Center, Albany, NY, ²Nephrology and Transplantation, University at Buffalo, Buffalo, NY, ³Center for Donation and Transplantation, Albany Medical Center, Albany, NY, ⁴Renal Transplant Program, Hines VA Medical Center, Chicago, IL
*Purpose: Kidney allocation has recently been modified to allow enhanced utilization of dual kidney transplants (DKT) to reduce organ discards. This study evaluates surgical complications…
2020 American Transplant Congress
Liver Transplant with Donation after Cardiac Death versus Donation after Brain Death Donors: Survival and Outcomes at 10 Years
O. Haque¹, E. Roth², A. Fleishman¹, K. Khwaja¹
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA, ²Harvard Medical School, Boston, MA
*Purpose: This observational study utilizes the SRTR database to assess liver transplant outcomes after Donation after Cardiac Death (DCD) versus Donation after Brain Death (DBD)…
2020 American Transplant Congress
Comparison of Specificity and Sensitivity of Clinical Viability Criteria to Assess Transplantability of High-Risk Donor Livers
H. Mergental¹, J. Hodson², R. W. Laing¹, Y. L. Boteon¹, J. Attard¹, L. Wallis³, A. Schlegel¹, P. Muiesan¹, M. Abradelo¹, M. P. Perera¹, D. Mirza⁴, S. C. Afford³
¹Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom, ²Department of Statistics, Queen Elizabeth Hospital, Birmingham, United Kingdom, ³Centre for Liver and Gastroenterology Research, University of Birmingham, Birmingham, United Kingdom, ⁴Liver Unit, Darius Mirza, Birmingham, United Kingdom
*Purpose: Normothermic machine perfusion (NMP) of the liver allows objective assessment before transplantation. To date, Birmingham (BC), Cambridge (CC) and Groningen Criteria (GC; Table 1A)…
2020 American Transplant Congress
Comparing Weight-Based Dosing of Envarsus XR in Obese and Non-Obese Renal Transplant Recipients
N. Breslin, N. Jandovitz, V. Nair, M. Abate, L. Teperman
North Shore University Hospital, Manhasset, NY
*Purpose: Tacrolimus has a narrow therapeutic window and significant inter- and intra-patient variability leading to variations in drug concentration. The recommended initial weight-based dose of…
2020 American Transplant Congress
Infectious Tolerance Depends Upon the ‘Exokine’ IL35
W. J. Burlingham¹, J. A. Sullivan¹, Y. Tomita², E. Jankowska-Gan¹, D. Lema¹, S. Hong³, D. A. Vignali⁴
¹Surgery, University of Wisconsin, Madison, WI, ²Surgery, Tokai University, Tokyo, Japan, ³Pharmacy, University of Wisconsin, Madison, WI, ⁴Immunology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Interleukin-35 (IL35) is an immunosuppressive cytokine composed of Ebi3 and p35 subunits. Yet the form(s) that IL35 assumes and its role in infectious tolerance,…
2020 American Transplant Congress
Comparison of Outcome Between Low-Dose Rabbit Anti-Thymocyte Globulin and Basiliximab in Low-Risk Living Donor Kidney Transplantation
S. Kim, M. Lim, J. Kwon, E. Jeong, J. Yang, K. Kim, K. Lee, O. Lee, J. Joh
Transplantation, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: For preventing immunological rejection after kidney transplantation, induction immunosuppressant agents such as basiliximab or rabbit anti-thymocyte globulin (r-ATG) are mostly used nowadays. We compared…
2020 American Transplant Congress
Clinical Significance of C4d and HLA-DSA on Post-Transplant Clinical Outcomes in Kidney Transplant Recipients with Antibody-Mediated Rejection
W. Park, O. Kwon, Y. Kim, J. Paek, K. Jin, S. Park, S. Han
Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institute, Daegu, Korea, Republic of
*Purpose: The clinicopathological diagnosis of rejection after kidney transplantation (KT) was well defined by Banff classification. In the diagnosis of antibody-mediated rejection (AMR), the presence…