Am J Transplant, Volume 20, Suppl 3 Archives - Page 18 of 223 - ATC Abstracts

2020 American Transplant Congress
Anticoagulation in Simultaneous Pancreas Kidney (SPK) Transplantation- On What Basis?
J. Gopal, P. Herbert, J. Crane, F. Dor, V. Papalois, A. Muthusamy
Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
*Purpose: Despite technical refinements, early pancreas graft loss due to thrombosis continues to occur. Conventional coagulation tests do not detect hypercoagulability and hence is left…
2020 American Transplant Congress
The Role of Complement-Split Products as Biomarkers for Acute Antibody-Mediated Rejection of Kidney Allografts
B. G. Abu Jawdeh¹, B. Campos-Naciff¹, K. Harrison¹, K. Meganathan¹, A. Kumar², M. Anand¹, A. Govil¹, E. S. Woodle¹, B. P. Dixon³
¹University of Cincinnati, Cincinnati, OH, ²All India Institute of Medical Sciences, New Delhi, India, ³University of Colorado, Aurora, CO
*Purpose: Acute antibody-mediated rejection (AMR) is mediated by the activation of the classical complement system in addition to non-complement dependent inflammatory pathways. Complement fixation by…
2020 American Transplant Congress
The Protective Effect of Hypothermic Oxygenated Machine Perfusion (HOPE) Onresuscitating Steatotic Liver and its Underlying Mechanism
F. Lin¹, F. Zhen¹, X. Yan¹, L. Wenjin¹, Y. Qifa²
¹Zhongnan Hospital of Wuhan University, Wuhan, China, ²Zhongnan Hospital of Wuhan University/The Third Xiangya Hospital of Central South University, Wuhan/Changsha, China
*Purpose: To analyze the impact of steatotic livers with conventional cold storage (CS) and hypothermic oxygenated perfusion (HOPE) approaches, and further to investigate the rescue…
2020 American Transplant Congress
XIAP Enhances Xenoislet Survival: Novel Models to Evaluate Pretransplantation Gene Modifications
G. R. Devi¹, Z. Fitch¹, M. Song¹, M. Ribeiro¹, A. McGowan¹, X. Luo², B. H. Collins¹, A. D. Kirk¹
¹Department of Surgery, Duke Univesity School of Medicine, Durham, NC, ²Division of Nephrology, Duke Univesity School of Medicine, Durham, NC
*Purpose: Porcine islet xenotransplantation offers a reliable and near limitless supply of islets for the treatment of type 1 diabetes. Intraportal infusion of cells exposes…
2020 American Transplant Congress
T Cells from Highly Sensitized Kidney Transplant Patients Display Distinct TCR Repertoires
S. Negi¹, M. Li¹, A. Rutman², S. Paraskevas¹, C. Polychronakos¹, J. Tchervenkov¹
¹RIMUHC, Montreal, QC, Canada, ²McGill University, Montreal, QC, Canada
*Purpose: Sensitization to HLA antigens limits patient’s access to renal transplantation and causes higher risk of acute rejection and graft loss. T-cells, B-cells and donor-specific…
2020 American Transplant Congress
Exploring Psychosocial Factors and Disparity in Liver Transplant
K. Schmidt
Dept. of Psychiatry & Behavioral Sciences, Emory University, Atlanta, GA
*Purpose: Trends in liver transplant (LT) have shifted, and increasingly, individuals with alcohol liver disease (ALD) are receiving LT without 6-months of sobriety (Lee &…
2020 American Transplant Congress
Machine Learning Improves Kidney Discard Predictability
M. Barah¹, S. Mehrotra²
¹IEMS Department, Northwestern University, Evanston, IL, ²IEMS Department, MEAS, Northwestern University, Evanston, IL
*Purpose: Despite the shortage of kidneys supply, 18%-20% of deceased donor kidneys are discarded annually.*Methods: The cohort consisted of adult deceased donor kidneys donated between…
2020 American Transplant Congress
Individualized Impact of Donation after Cardiac Death on Kidney Transplant Outcomes
S. Bae, A. Massie, J. Garonzik Wang, D. Segev
Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Increasing the use of kidneys from donation after cardiac death (DCD) donors is a potential solution to mitigate the current organ shortage. However, DCD…
2020 American Transplant Congress
Pre-Transplant Detection of Anti-at1r Antibodies and Pediatric Kidney Transplantation Outcomes
K. Hitchman¹, C. Usenko², R. Hinojosa¹, D. Ranch¹
¹UT Health San Antonio, San Antonio, TX, ²University Health System, San Antonio, TX
*Purpose: Describe correlations between pre-transplant (PreTXP) presence of anti-angiotensin II receptor type 1 antibodies (AT1R Ab) and post-transplant (PostTXP) outcomes in a pediatric kidney transplant…
2020 American Transplant Congress
Effect of Discordant Kidney Function at Transplant: A Single Center Analysis of Deceased Donor Paired Kidneys
E. Abuhelaiqa¹, M. Alkadi¹, S. Mansour², L. Mathew¹, F. Makableh¹, A. Nauman¹, O. Fituri¹, M. Asim¹, R. Fadhil³, H. A. Al-Malki¹
¹Nephrology, Hamad Medical Corporation, Doha, Qatar, ²Internal Medicine, Hamad Medical Corporation, Doha, Qatar, ³Transplant Surgery, Hamad Medical Corporation, Doha, Qatar
*Purpose: Analysis of paired kidneys from deceased donors has the advantage of eliminating donor and center related biases seen in previous studies that evaluated kidney…