Am J Transplant, Volume 20, Suppl 3 Archives - Page 179 of 223 - ATC Abstracts

2020 American Transplant Congress
The Role of Th17 Polarized T Regulatory Cells in Intestinal Transplant Rejection
L. Belyayev¹, M. Sadat², J. Kang², K. Loh², A. Duttargi², S. Moturi², K. Khan², J. Hawksworth², C. Matsumoto², T. Fishbein², A. Kroemer²
¹Walter Reed National Military Medical Center, Bethesda, MD, ²MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Despite profound advances in immunosuppression, intestinal transplantation (ITx) is plagued by frequent cellular rejection. T regulatory cells (Tregs) are key in mitigating immune cell…
2020 American Transplant Congress
Galectin-3 as a Biomarker of Disease Severity in Acute-on-Chronic Liver Failure
E. Cervantes-Alvarez¹, F. Tejeda-Dominguez², M. Lizardo-Thiebaud², E. Alatorre-Arenas³, O. Méndez-Guerrero¹, S. Yarza-Regalado¹, D. Kershenobich¹, A. Torre¹, M. Vilatobá⁴, C. A. Huang⁵, N. Navarro-Alvarez¹
¹Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ²Molecular Biology, Panamerican University, School of Medicine, Mexico City, Mexico, ³University of the Americas Puebla, School of Medicine, Puebla, Mexico, ⁴Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Surgery, University of Colorado Anschutz Medical Campus, Denver, CO
*Purpose: A matter of great importance is the discovery of alternative diagnostic measures that can detect liver disease at an early stage, especially when at…
2020 American Transplant Congress
Prolonged Cold Ischemia Increases Reactive Oxygen Species Activates Autophagy by Enhancing Glycolysis in the Graft Through the mTOR Signaling Pathway in Orthotopic Lung Transplantation of Rats
H. Lin¹, S. Dai², W. Liu³, X. Lin², B. Yu², S. Chen³, S. Liu², J. Tang²
¹Thoracic Surgery, Wuhan University, Renmin Hospital, Wuhan, China, ²Thoracic Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China, ³Department of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, China
*Purpose: The aim of the present study is to investigate the mechanisms by which prolonged CI influences the autophagy in the graft lung, in which…
2020 American Transplant Congress
Bortezomib Exhibits Therapeutic Implication in Renal Interstitial Fibrosis after Kidney Transplantation by Inhibiting Akt-mTOR-P70S6K-Smurf2 Pathway and Stabilizing IκBα Protein
C. Suo, Z. Gui, Z. Wang, J. Zhou, M. Zheng, H. Chen, S. Fei, L. Sun, X. Zhang, M. Gu, R. Tan
Jiangsu Province Hospital, Nanjing, China
*Purpose: Allograft interstitial fibrosis and fibrogenesis significantly exacerbate the progression of chronic allograft disease (CAD) and are essential therapeutic targets. Epithelial‐mesenchymal transition (EMT) is recognized…
2020 American Transplant Congress
Evaluating Postoperative Opioid Requirements of Kidney Transplant Recipients
M. A. Muir¹, K. R. Szempruch², R. E. Dupuis¹, A. H. Toledo³, P. Serrano Rodriguez³
¹Pharmacotherapy and Experimental Therapeutics, UNC Eshleman School of Pharmacy, Chapel Hill, NC, ²Pharmacy, UNC Medical Center, Chapel Hill, NC, ³Surgery - Transplant, UNC Medical Center, Chapel Hill, NC
*Purpose: Multimodal analgesia with non-opioid analgesics in the setting of enhanced recovery after surgery (ERAS) pathway has proven beneficial in managing pain and decreasing adverse…
2020 American Transplant Congress
Decision-Making, Motivations and the Donation Experience among HLA-Identical Living Kidney Donors at UCLA – A Qualitative Study
E. L. Wood¹, S. George², N. Kogut¹, E. Lum³, J. Veale¹
¹Urology, UCLA, Los Angeles, CA, ²Fielding School of Public Health, UCLA, Los Angeles, CA, ³Medicine, Nephrology, UCLA, Los Angeles, CA
*Purpose: Studies on motivations and decision-making processes of living donors have previously identified recipient relationship, fear of loss and altruism as important modifying factors of…
2020 American Transplant Congress
New Onset Diabetes after Transplant (NODAT) in Hispanic Kidney Transplant Recipients: A Multi-Center Retrospective Study
R. Alsheikh¹, L. Kodali², O. Alfayez³, M. Alshibani¹, A. Basilim¹, M. Fazel⁴
¹King Abdulaziz University, Jeddah, Saudi Arabia, ²Mayo Clinic, Scottsdale, AZ, ³Qassim University, Buraydah, Saudi Arabia, ⁴University of Arizona, Tucson, AZ
*Purpose: Hispanic ethnicity is one of the reported risk factors for NODAT in kidney transplant recipients (KTR). The purpose of our study is to determine…
2020 American Transplant Congress
Pre-Donation CKD-EPI GFR is Superior to Iothalamate Split Scan Results in Predicting 6-Month Post-Nephrectomy Donor Kidney Function
J. R. Montgomery, A. Zondlak, C. S. Brown, A. Pinsky, K. Walsh, J. Kozlowski, E. A. Herriman, Y. Lu, R. S. Sung, K. J. Woodside
General Surgery, University of Michigan, Ann Arbor, MI
*Purpose: Predicting post-donation GFR remains a challenge during living kidney donor (LKD) evaluation. Iothalamate split scans have been employed during LKD evaluation to document measured…
2020 American Transplant Congress
Deleterious Effect of Intravenous Steroids on Bone Mineral Density in Patients Treated for Borderline Rejection of the Renal Allograft
S. T. Suliman, D. O. Hodge, M. B. Prendergast
Transplant Nephrology, Mayo Clinic, Jacksonville, FL
*Purpose: Subclinical rejection of the renal allograft is known to increase the risk of developing interstitial fibrosis and tubular atrophy which ultimately translates into shortening…
2020 American Transplant Congress
Peritoneal Dialysis in Delayed Graft Function, a Safe and Effective Option
A. Gardezi, B. Muth, F. Aziz, N. Garg, M. Mohamed, A. Djamali, D. Mandelbrot, S. Parajuli
University of Wisconsin, Madison, WI
*Purpose: Peritoneal dialysis (PD) has been utilized increasingly in the past decade. Many of these patients undergo transplantation and may require dialysis for delayed graft…