ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Genome-Wide Analysis of Epstein Barr Virus Identifies Variations in the Latency Gene EBNA3C That Are Associated with Post Transplant Lymphoproliferative Disorder

    E. Maloney, J. Toh, S. M. Krams, C. O. Esquivel, O. M. Martinez

    Stanford University Sch of Med, Stanford, CA

    *Purpose: Epstein Barr virus (EBV) is a gamma herpes virus that is associated with a variety of human malignancies including EBV+ B cell lymphomas in…
  • 2020 American Transplant Congress

    Tissue Specificity and the Role of Lymphocytes in Estrogen-Mediated Protection from Renal Ischemia Reperfusion Injury

    P. T. Hernandez, C. S. O'Brien, S. J. Concors, L. N. Krumeich, Z. Wang, G. Ge, W. Hancock, M. H. Levine

    Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to delayed graft function (DGF) in kidney transplantation. We previously demonstrated lower rates of DGF…
  • 2020 American Transplant Congress

    Tonic-Signaling Chimeric Antigen Receptors Drive Exhaustion in Regulatory T Cells

    C. Lamarche1, C. Mackall2, E. Weber3, M. Levings4

    1University of British Columbia, Vancouver, BC, Canada, 2Stanford University School of Medicine, Standford, CA, 3Stanford University School of Medicine, Stanford, CA, 4Surgery, University of British Columbia and BC Children's Hospital Research Institute, Vancouver, BC, Canada

    *Purpose: Regulatory T cells (Tregs) and chimeric antigen receptor (CAR) Tregs are a promising cell therapy to prevent or treat autoimmune diseases or allograft rejection.…
  • 2020 American Transplant Congress

    Evaluation of an Opioid Restrictive Pain Management Initiative in Adult Kidney Transplant Recipients

    S. Tischer1, S. Maryan2, L. Pacurar1, S. Kumar1, S. Waits1, M. Englesbe1, R. Sung1, K. McMurry1

    1Michigan Medicine - University of Michigan, Ann Arbor, MI, 2ProHealth Care, Milwaukee, WI

    *Purpose: Recent national policy changes make it imperative to implement practices to reduce opioid prescribing. Despite the importance, evidence to guide opioid utilization following kidney…
  • 2020 American Transplant Congress

    First Case of Simultaneous Living Related Parathyroid- and Kidney Transplantation Into a Child

    N. Vallant1, M. Sinha2, P. Gogalniceanu1, M. Cheung2, C. Boffa3, M. Irving2, P. Carroll2, J. Hubbard1, R. Gokmen1, N. Ware2, N. Mamode1, N. Kessaris1

    1Renal Transplant and Vascular Access, Guy's Hospital London, London, United Kingdom, 2Renal Transplant and Vascular Access, Evelina London Children's Hospital, London, United Kingdom, 3Renal Transplant and Vascular Access, Portsmouth Hospitals NHS Trust, London, United Kingdom

    *Purpose: Inherited hypoparathyroidism can lead to life threatening episodes of hypocalcaemia as well as to end stage renal failure at a young age. We are…
  • 2020 American Transplant Congress

    Waitlist Mortality in Children with Biliary Atresia: A Competing Risks Analysis

    I. A. Ziogas, F. Ye, Z. Zhao, L. K. Matsuoka, M. I. Montenovo, S. P. Alexopoulos

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Biliary atresia (BA) is the most common indication for liver transplant (LT) in children. The current PELD allocation algorithm does not accurately reflect the…
  • 2020 American Transplant Congress

    Characterizing the Landscape and Impact of Infections Following Kidney Transplantation

    K. R. Jackson, J. Motter, R. Avery, W. Werbel, A. Massie, J. Garonzik-Wang, D. Segev

    Johns Hopkins University, Baltimore, MD

    *Purpose: Infections remain a major threat to successful kidney transplantation (KT), although there is limited data on the spectrum and clinical consequences of a post-KT…
  • 2020 American Transplant Congress

    Thymic B Cells: A Means to Control Regulatory Tolerance

    C. LeGuern1, S. Germana1, N. Feeney1, Z. Wang2, N. Tanimine1, C. Huang3, C. Rickert1, J. Markmann1

    1Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, 2University of Colorado Denver, Aurora, CO, 3Surgery, University of Colorado Denver, Aurora, CO

    *Purpose: Therapies involving CD4 regulatory T cells (Tregs) are promising approaches to mitigate graft rejection and autoimmunity. Understanding of the activation mechanisms that initiate Treg…
  • 2020 American Transplant Congress

    Dual Donor-Recipient Intervention with Recombinant Human C1 Inhibitor Prevents Delayed Graft Function and Reduces Antibody-Mediated Rejection after Kidney Transplantation in Non-Human Primates

    C. Blanton1, J. Reyes1, M. Eerhart1, P. Chlebeck1, M. Springer1, Y. Ponstein2, E. vanAmersfoort2, J. Torrealba3, Y. Yankol1, A. D’Alessandro1, L. Fernandez1

    1University of Wisconsin, Madison, WI, 2Pharming Technologies BV, Leiden, Netherlands, 3Pathology, UTSouthwestern, Dallas, TX

    *Purpose: Patients with delayed graft function (DGF) are at increased risk for rejection and inferior graft survival. Complement activation during brain death and ischemia reperfusion…
  • 2020 American Transplant Congress

    Comparative Study between ATG and Grafalon as Induction Agent in Renal Transplant Recipient

    L. K. Das, P. Paudyal, S. Shrestha, B. Shahi, A. Pandey, R. Verma, P. Chandra Shrestha

    Kidney and Liver Transplant, Shahid Dharmabhakta National Transplant Center, Kathmandu, Nepal

    *Purpose: Renal transplantation (Rtx) remains the most effective treatment for of end-stage renal disease (ESRD). The development of induction therapy has significantly reduced the incidence…
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