ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Implementation of a Pharmacist in an Adult Transplant Outpatient Clinic (Kidney, Liver, Pancreas): A Pilot Study – Implant

    P. Leveille-Dugas1, C. Bernard1, L. Loiselle1, Y. Zhang1, C. Coursol1, K. Mousseau1, N. Sheehan1, M. Cantarovich2

    1Pharmacy, McGill University Health Centre, Montréal, QC, Canada, 2Division of Nephrology, Department of Medicine, McGill University Health Centre, Montréal, QC, Canada

    *Purpose: Solid organ transplant (SOT) patients require a complex medication regimen which increases the risk of many drug-related problems. The purpose of this study was…
  • 2020 American Transplant Congress

    Barriers to Organ Transplantation among Underrepresented Racial and Ethnic Groups

    M. Parra

    Duke Clinical Research Institute, Durham, NC

    *Purpose: To understand how known patient, provider, and system-level barriers to organ transplantation differ by race and ethnicity.*Methods: We searched Pubmed and Scopus for articles…
  • 2020 American Transplant Congress

    Vaccine Safety Concerns and Relationship to Comfort with Provider Communication in a Population of Inner-City Kidney Transplant Recipients

    T. Morancy, I. Nadeem, G. Cordero, D. Lee, M. Markell

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Misperceptions and incorrect beliefs among patients may contribute to patient refusal of vaccines. We examined beliefs and sources of information in a population of…
  • 2020 American Transplant Congress

    Post Heart Transplant Outcomes for Patients with Cardiac Sarcoidosis

    G. S. Liu1, E. C. DePasquale1, A. M. Wolfson2, R. R. Chand3, P. Banankhah1, J. Nattiv1, A. D. Salimbangon4, P. A. Genyk1, P. A. Kingsford1, J. P. Li1, D. Vucicevic5, K. Pandya1, J. Rahman1, M. Fong1, A. S. Vaidya1

    1Keck Medicine of USC, Los Angeles, CA, 2University of Arizona Sarver Heart Center, Tucson, AZ, 3Harbor-UCLA Medical Center, Los Angeles, CA, 4UCLA Medical Center, Los Angeles, CA, 5Newark Beth Israel Medical Center, Newark, NJ

    *Purpose: Cardiac sarcoidosis (CS) is a known etiology of end-stage dilated, hypertrophic, or arrhythmogenic cardiomyopathies requiring heart transplantation (HT). We sought to evaluate the long-term…
  • 2020 American Transplant Congress

    Effects of Alpha-1 Proteinase Replacement Continuation Post-Lung Transplantation in Alpha-1 Antitrypsin Deficiency: A Single Center Case Series

    M. Bremer, A. Feist, M. Mariski, G. Yung, T. Floreth, E. Schonhoft, G. Schooler, E. Golts, K. Afshar

    Lung Transplant, University of California San Diego, La Jolla, CA

    *Purpose: Alpha-1 antitrypsin deficiency (AATD) accounts for approximately 6% of all lung transplants (LTx) performed annually. The benefit of replacement with alpha-1 proteinase inhibitor (A1-PI)…
  • 2020 American Transplant Congress

    Evaluation of the Mitra Microsampling Device for TTV Measurement in Human Whole Blood of Lung Transplant Recipients

    J. Mühlbacher1, B. Lickefett1, K. Doberer2, B. Reiter3, S. Aberle4, G. Bond2, P. Jaksch1

    1Department of Surgery, Medical University of Vienna, Vienna, Austria, 2Department of Medicine III, Medical University of Vienna, Vienna, Austria, 3Clinical Institute of Laboratory Medicine, Medical University of Vienna, Vienna, Austria, 4Department of Virology, Medical University of Vienna, Vienna, Austria

    *Purpose: The apathogenic Torque Teno Virus (TTV) is highly prevalent among solid organ transplant recipients and mirrors the immunocompetence of its host. qPCR based measurement…
  • 2020 American Transplant Congress

    Donor-Derived Cell-Free DNA May Not Discriminate Rejection in Kidney Transplant Recipients with a Prior Allograft in Place

    A. Vo, M. Gillespie, S. C. Jordan, A. Peng, R. Najjar, S. Sethi, K. Lim, N. Ammerman, E. Huang

    Cedars-Sinai, Los Angeles, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is an injury biomarker discriminating rejection in kidney transplant (KTx) patients (pts). However, its performance when stratified by rejection risk…
  • 2020 American Transplant Congress

    Single Cell RNA Sequencing of Murine Kidney Allografts Identifies Macrophage Gene Signature Associated with Acute Rejection

    A. Dangi1, N. Natesh2, M. Monal1, J. Wang3, X. Shen2, X. Luo1

    1Nephrology/Medicine, Duke University, Durham, NC, 2Biomedical Engineering, Duke University, Durham, NC, 3Surgery, Duke University, Durham, NC

    *Purpose: Evaluating kidney allografts using single cell RNA sequencing (scRNAseq) can provide a comprehensive qualitative and quantitative gene expression data on thousands of individual cells.…
  • 2020 American Transplant Congress

    Anti-CD321 Antibody (90G4) Protects Liver against Ischemia Reperfusion Injury in a Murine Model

    E. Yin1, T. Fukuhara2, H. Bashuda1, K. Uchida3

    1Atopy Research Center, Juntendo University School of Medicine, Tokyo, Japan, 2Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan, 3Juntendo Advanced Research Institute for Health Science, Juntendo University School of Medicine, Tokyo, Japan

    *Purpose: Ischemia reperfusion results in increased transmigration of leukocytes into tissue. This eventually leads to post transplant graft damage after organ transplantation. CD321 (also known…
  • 2020 American Transplant Congress

    IL-10 Exposure Enhances IRAK-M Expression to Promote Endotoxin Tolerance and the T Cell Tolerogenic Potential of Liver Conventional DCs

    Y. Zheng, R. Nakano, A. Thomson

    Surgery, Starzl Transplantation Institute, Pittsburgh, PA

    *Purpose: Liver conventional myeloid (m)DC contribute to liver transplant tolerance. When freshly-isolated, they produce low levels of IL-12 but high levels of IL-10 compared with…
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