Am J Transplant, Volume 20, Suppl 3 Archives - Page 175 of 223 - ATC Abstracts

2020 American Transplant Congress
Noninvasive Imaging of CD122+ T Cells via Immuno-PET for Detection of Acute Cellular Rejection
A. J. Matar¹, B. P. Lovasik¹, D. Vanover², L. Rotolo², Y. Dong¹, D. A. Faber¹, D. V. Mathews¹, W. H. Kitchens¹, P. Santangelo², A. B. Adams¹
¹Surgery and Transplantation, Emory University, Atlanta, GA, ²Biomedical Engineering, Georgia Tech, Atlanta, GA
*Purpose: Acute cellular rejection (ACR) remains a clinically important problem following organ transplantation. Clinically, suspicion of ACR is dependent upon serum laboratory values, and diagnosis…
2020 American Transplant Congress
Low Physiochemical Immunogenicity Scores Improve Long-Term Survival of Deceased Donor Kidney Transplants
D. Bekbolsynov¹, B. Mierzejewska¹, J. Borucka², S. A. Khuder¹, M. Rees¹, R. Green³, S. Stanislaw¹
¹University of Toledo, Toledo, OH, ²Parexel Corp., Warsaw, Poland, ³Bowling Green State University, Bowling Green, OH
*Purpose: A severe shortage of deceased donor kidneys limits access to kidney transplantation. Limited longterm graft function exacerbates this shortage as 12% of the waiting…
2020 American Transplant Congress
Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, I. Yakubu¹, S. Paluri¹, A. Chachar¹, J. Chang², I. Moinuddin¹, L. Kamal¹, M. Levy¹, C. Bhati¹, A. King¹, P. Kimball¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²ATAGC, Edmonton, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. Basic and…
2020 American Transplant Congress
No Kidney after Liver Left Behind: An Analysis of the Organ Procurement and Transplantation Network “Safety Net” Policy
T. C. Lee, K. Wima, M. C. Morris, A. Kassam, S. A. Shah, R. Quillin
Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: Liver transplant (LT) recipients who develop persistent renal dysfunction face increased morbidity and mortality. These patients may be eligible for prioritization on the kidney…
2020 American Transplant Congress
Change in the Willingness of Transplant Candidates to Accept Hepatitis C Virus Positive Deceased Donor Organs in the Era of Direct-Acting Antivirals
Q. Yuan, S. Hong, E. Roth, M. Sise, E. Bethea, W. Williams, H. Yeh, N. Elias
Transplant Center, Massachusetts General Hospital，Harvard Medical School, Boston, MA
*Purpose: Direct-acting antiviral (DAA) medications’ advent in 2014 very effectively changed the hepatitis C virus (HCV) treatment landscape and allowed post-transplant HCV therapy. We aimed…
2020 American Transplant Congress
Does the New Heart Transplantation Allocation System Improve Access to Transplantation for Restrictive and Hypertrophic Cardiomyopathy Patients? A UNOS Database Analysis
R. Y. Loyaga-Rendon¹, D. R. Fermin¹, M. Jani¹, R. L. Grayburn¹, S. Lee¹, M. G. Dickinson¹, M. Gonzalez¹, N. K. Shrestha², T. Boeve³, S. Jovinge², M. Leacche³
¹Cardiology, Spectrum Health, Grand Rapids, MI, ²DeVos Cardiovascular Research Program, Spectrum Health, Grand Rapids, MI, ³Cardiothoracic Surgery, Spectrum Health, Grand Rapids, MI
*Purpose: Historically, patients with end-stage restrictive (RCM) and hypertrophic cardiomyopathy (HCM), experienced longer wait times and increased waitlist mortality while awaiting a heart transplant (HT)…
2020 American Transplant Congress
Transplant Monitoring and PTLD Detection with B Cell Receptor Repertoire Analysis in a Large Prospective Pediatric Cohort
K. Jackson¹, O. Martinez², S. Krams², M. Robien³, M. Lapasaran², B. Armstrong⁴, C. Twist⁵, K. Weinberg⁶, D. Gratzinger¹, B. Tam¹, M. Sever⁴, M. Brown³, D. Bernstein⁶, C. Esquivel², S. D. Boyd¹
¹Department of Pathology, Stanford Univ School of Med, Stanford, CA, ²Department of Surgery/Division of Abdominal Transplantation, Stanford Univ School of Med, Stanford, CA, ³NIAID, NIH, Bethesda, MD, ⁴Rho, Chapel Hill, NC, ⁵Roswell Park, Buffalo, NY, ⁶Department of Pediatrics, Stanford Univ School of Med, Stanford, CA
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is a…
2020 American Transplant Congress
The Centers for Medicare and Medicaid Services’ Proposed Metrics for Recertification of Organ Procurement Organizations: Evaluation by the Scientific Registry of Transplant Recipients
J. Snyder¹, D. Musgrove¹, D. Zaun¹, A. Wey¹, N. Salkowski¹, J. Rosendale², A. Israni¹, R. Hirose³, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²UNOS, Richmond, VA, ³Department of Surgery, Univ of California, San Francisco, San Francisco, CA
*Purpose: On December 23, 2019, the US Centers for Medicare and Medicaid Services proposed two new standards that organ procurement organizations (OPOs) must meet for…
2020 American Transplant Congress
Kidney Procurement Biopsy Technique Does Not Determine Histologic Accuracy
V. Shah, K. King, S. Coley, G. Dube, D. Cohen, S. Mohan, S. Husain
Medicine-Nephrology, Columbia University, New York, NY
*Purpose:Procurement biopsies (PBx) are commonly used to evaluate the quality of deceased donor kidneys (DDK). However, the validity of PBx biopsy interpretation has been questioned,…
2020 American Transplant Congress
The Effects of DGF after Deceased Donor Renal Transplantation Differ by KDPI
M. Molinari¹, W. Chang¹, D. Jorgensen², C. Wu³, S. Hariharan³
¹Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, ²Biostatistics, University of Pittsburgh Medical Centre, Pittsburgh, PA, ³Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA
*Purpose: We analyzed the effects of DGF on: (1) graft survival, (2) patient survival and (3) eGFR of adult recipients of deceased donor kidney transplants…