Am J Transplant, Volume 20, Suppl 3 Archives - Page 170 of 223 - ATC Abstracts

2020 American Transplant Congress
Crispr-Based Diagnostics for Rejection and Opportunistic Infection Detection in Kidney Transplantation
I. T. Lape¹, M. M. Kaminski², E. Akalin³, J. Collins², L. W. Riella¹
¹Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA, ²Institute for Medical Engineering and Science and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, ³Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY
*Purpose: There is an unmet need in transplantation to identify allograft injury non-invasively. More than 50% of patients with kidney transplants lose their grafts within…
2020 American Transplant Congress
Mitochondrion-Endothelial Interaction Generates Danger Signal in Promoting Costimulation-Resistant T Cell-Mediated Allograft Rejection
S. Li¹, M. Song¹, Q. Li², A. Kirk¹, H. Xu¹
¹Surgery, Duke University, Durham, NC, ²Immunology, Duke University, Durham, NC
*Purpose: Endothelial cells (ECs) play a critical role in allorecognition, presentation, and costimulation for initiation of alloimmune rejection. The objective of this study was to…
2020 American Transplant Congress
Belatacept Every Two Month Maintenance Dosing in Kidney Transplantation: A Randomized, Non-Inferiority Trial
I. R. Badell, R. Parsons, S. Mead, S. Thomas, G. Karadkhele, S. Pastan, C. Larsen
Emory University School of Medicine, Atlanta, GA
*Purpose: Maintenance immunosuppression with belatacept following kidney transplantation results in a reduced risk of patient death and graft loss as compared to calcineurin inhibitors. However,…
2020 American Transplant Congress
Recurrent Lupus Post Kidney Transplantation- The Histological and Clinical Characteristics
A. Bentall¹, W. Jiqiu², A. Kattah¹, M. L. Gonzalez Suarez³, F. G. Cosio¹, M. Mai⁴, H. Khamash⁵, M. D. Stegall⁶, H. Amer¹, L. D. Cornell⁷, F. Fervenza¹, M. P. Alexander⁷
¹Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²National Clinical Research Center of Kidney Diseases, Nanjing University, Nanjing, China, ³Department of Nephrology, University of Mississippi Medical Center, Jackson, MS, ⁴Division of Nephrology and Hypertension, Mayo Clinic, Jackonville, FL, ⁵Division of Nephrology and Hypertension, Mayo Clinic, Scottdale, AZ, ⁶Department of Transplant Surgery, Mayo Clinic, Rochester, MN, ⁷Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: Lupus nephritis (LN) progresses to ESRD in
2020 American Transplant Congress
Offspring to Parent Living Donor Liver Transplantation: An Analysis of the A2ALL Database
R. A. Choudhury¹, H. J. Braun², J. D. Grab², J. L. Dodge², H. B. Moore¹, D. Yoeli¹, J. J. Pomposelli¹, T. Nydam¹, N. L. Ascher², E. A. Pomfret¹, J. P. Roberts²
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Department of Surgery- Division of Transplantation Surgery, University of California, San Francisco, San Francisco, CA
*Purpose: Recently, there have been concerns regarding inferior graft survival following offspring to parent kidney transplantation due to issues related to alloimmunity during pregnancy. It…
2020 American Transplant Congress
Reduced Dose Valganciclovir is Effective for CMV Prevention without Excess Breakthrough or Resistance in Kidney Transplantation
M. Luu¹, P. Klem¹, B. Crowther¹, M. Abidi², M. Miller¹, K. Schoeppler¹, S. Davis²
¹Pharmacy, University of Colorado Hospital, Aurora, CO, ²Medicine, University of Colorado, Aurora, CO
*Purpose: Reduced dose valganciclovir (VGC) (450 mg daily) may be a useful alternative to full dose VGC for cytomegalovirus (CMV) prophylaxis due to drug cost…
2020 American Transplant Congress
Calculating the Lung Allocation Score Error for ECMO Patients
N. Dussault¹, J. Katsis², E. Garrity¹, M. M. Churpek³, W. F. Parker¹
¹University of Chicago, Chicago, IL, ²Vanderbilt University, Nashville, TN, ³University of Wisconsin, Madision, WI
*Purpose: The use of extracorporeal membranous oxygenation (ECMO) as a bridge to lung transplantation has increased dramatically. However, the Lung Allocation Score (LAS) does not…
2020 American Transplant Congress
Preformed Donor Specific Antibody and Mfi-Dependent Effects in Simultaneous Liver-Kidney Transplantation
V. Fleetwood, C. Papageorge, D. Aufhauser, G. Leverson, B. Welch, L. Hidalgo, D. Foley, Y. Yankol, A. D'Alessandro, D. Al-Adra, R. Redfield, J. Mezrich
Department of Transplantation, University of Wisconsin, Madison, WI
*Purpose: Preformed donor specific antibody to HLA Class II (pDSA) is suggested to be an independent risk factor for mortality in simultaneous liver and kidney…
2020 American Transplant Congress
Generation of Insulin-Producing Cells via Multiplex Epigenetic Engineering of Human Somatic Cells in 2 Weeks
R. A. Naqvi¹, W. Zhang¹, A. Isidan¹, C. Evans-Molina², J. A. Fridell¹, P. Li¹, B. Ekser¹
¹Division of Transplant Surgery, Indiana University, Indianapolis, IN, ²Diabetes Research Center, Indiana University, Indianapolis, IN
*Purpose: Stem cell-derived β-cells not only promise a renewable supply of insulin-producing cells with negligible immunosuppression but may also provide a substrate for the identification…
2020 American Transplant Congress
Initial North American Experience in Renal Transplantation from Medical Assistance in Dying Donors
M. A. Levine, S. Sami, A. Sener, P. Luke
Surgery, London Health Sciences Centre, London, ON, Canada
*Purpose: In 2016, Canadian federal legislation was passed creating a regulatory framework for medical assistance in dying (MAiD) for individuals who are suffering from a…