ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Alternate Triazole Therapy for Breakthrough Invasive Fungal Disease in Lung Transplant Recipients on Triazole Prophylaxis

    A. Abbas, H. Hassouna, F. Marco Canosa, K. D. Brizendine

    Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Invasive fungal diseases (IFD) are a leading cause of infection related morbidity and mortality in lung transplant (LT) recipients. Data regarding outcomes of breakthrough…
  • 2020 American Transplant Congress

    Impact of Donor Lung Pathogenic Bacteria Detected by Next-Generation Sequencing on Early Post-Transplant Outcomes in Lung Transplant Recipients

    D. Liu, J. Zhang, J. Chen

    Lung Transplant Center, Wuxi People's Hospital, Wuxi, China

    *Purpose: The effect of donor lung pathogenic bacteria on the prognosis of lung transplantation is not clear. We used the technique of next-generation sequencing (NGS)…
  • 2020 American Transplant Congress

    The Use of dd-cfDNA as a Predictive Tool for Future Proteinuria

    S. Jordan1, P. Sood2, J. Bromberg3, D. Brennan4

    1Cedars-Sinai, Los Angeles, CA, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3University of Maryland, Baltimore, MD, 4The Johns Hopkins Hospital, Baltimore, MD

    *Purpose: Most allografts with proteinuria >1500 mg/dL have new glomerular pathology. In contrast, lower levels of proteinuria are generally associated with non-glomerular, nonspecific histologic changes.…
  • 2020 American Transplant Congress

    A Mouse Model of Paratopic Intestinal Transplantation to Delineate GVHD-Free Alloimmune Rejection Responses

    A. Dangi1, J. Wang2, A. Joseph3, J. Roper3, N. Surana4, X. Luo1

    1Nephrology/Medicine, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC, 3Gastroenterology/Medicine, Duke University, Durham, NC, 4Molecular Genetics and Microbiology, Duke University, Durham, NC

    *Purpose: Current clinical practice of intestinal transplantation is limited due to a high rate of graft failure and patient mortality. In the present study, we…
  • 2020 American Transplant Congress

    Rat Hind Limb Transplant Model to Assess Vascularized Composite Allograft (VCA) Inflammation and Ischemia Reperfusion Injury

    Z. Wang1, A. B. Harrant1, Y. Wang1, K. Washington1, E. Farkash2, C. A. Huang1

    1Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, 2Pathology, University of Michigan, Ann Arbor, MI

    *Purpose: Vascularized composite allografts are potential surgical solutions for patients with traumatic or disfiguring injuries but are highly immunogenic and require elevated levels of immunosuppression.…
  • 2020 American Transplant Congress

    Human Live Donor Liver Transplantation is Associated with Pd-l1 Expression on Donor-Exosome-Acquiring Host Dendritic Cells

    D. Lema, E. Jankowska-Gan, D. Al-Adra, W. Burlingham

    Surgery- Transplantation, University of Wisconsin-Madison, Madison, WI

    *Purpose: Liver transplantation (LTx) has been associated with the phenomenon of “cross-dressing” of recipient dendritic cells (DCs) by donor exosome-derived MHC antigens, and acquisition of…
  • 2020 American Transplant Congress

    Impact of UNOS Acceptance Sequence Number on Liver Graft Survival

    C. Thornley, O. Kezirian, S. Mehta, J. Cashman, J. Brink, T. Chaly Jr, W. Van der Werf

    University of Arizona/Banner University Medical Center Phoenix, Phoenix, AZ

    *Purpose: Many initially declined liver grafts will go on to be successfully transplanted into other candidates. Limited information exists regarding outcomes of liver grafts that…
  • 2020 American Transplant Congress

    Enough Initial Tacrolimus Blood Concentration is Crucial Even with Additional Everolimus in Corticosteroid Early Withdrawal Regimen for Kidney Transplant Recipients

    H. Sasaki1, T. Tanabe1, H. Higuchi1, T. Tsujimoto2, H. Harada1

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, 2Pharmacy, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: Everolimus (EVR) in combination with low-dose calcineurin inhibitor has been demonstrated in clinical trials to have comparable efficacy in low immunological risk kidney transplant…
  • 2020 American Transplant Congress

    Safely Increasing the Number of Renal Transplants Performed in a Small Center Through the Use of Acute Kidney Injury Donors

    S. Batie1, K. Eid2, K. Gabrys3, F. Barrantes3, B. Trujillo2, H. Kerr2

    1Presbyterian Healthcare Services, University of New Mexico Health Sciences Center, Albuquerque, NM, 2Presbyterian Healthcare Services, Albuquerque, NM, 3Renal Medicine Associates, Presbyterian Healthcare Services, Albuquerque, NM

    *Purpose: New Mexico is medically underserved state with a significant end-stage renal disease population. This study aims to further demonstrate the safety of utilizing AKI…
  • 2020 American Transplant Congress

    Active Vitamin D Prior to Transplant Affects Post-Transplant Outcomes

    L. Al Dahabreh1, C. Abou-Mitri1, L. Negrea1, K. Chavin2, T. Srinivas1, A. Padiyar1

    1Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Little is known regarding optimizing waitlist management of end stage renal disease to improve post-transplant outcomes. Active vitamin D is associated with improved outcomes…
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