2020 American Transplant Congress
National Trends in Locoregional Therapy among Liver Transplant (LT) Candidates with Hepatocellular Carcinoma (HCC) in the United States
1Stanford University, Redwood City, CA, 2University of California, San Francisco, San Francisco, CA
*Purpose: Advances in locoregional therapy (LRT) have expanded treatment options for patients with HCC. As recent policy changes in the United States (US) have lengthened…2020 American Transplant Congress
Salvaging Discarded Livers with Normothermic Machine Perfusion: Is it Worth the Cost?
Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: Normothermic machine perfusion (NMP) enables transplantation of discarded grafts with excellent outcomes in clinical trials. The cost of deploying NMP is often cited as…2020 American Transplant Congress
Heart Transplant Outcomes in Patients Who Receive Hepatitis B Virus-Positive Donor Hearts: A UNOS Registry Analysis
*Purpose: Hepatitis B infection in post-transplant patients posed a challenge in the setting of immunosuppression. However, the advent of anti-viral therapy for HBV has made…2020 American Transplant Congress
Gasdermin-D Mutation is Protective against Renal Ischemia Reperfusion Injury
*Purpose: Pyroptosis, a pro-inflammatory form of cell death, is dependent on membrane pore formation through the assembly of cleaved Gasdermin-D molecules. We hypothesized that this…2020 American Transplant Congress
Noninvasive Imaging of CD122+ T Cells via Immuno-PET for Detection of Acute Cellular Rejection
*Purpose: Acute cellular rejection (ACR) remains a clinically important problem following organ transplantation. Clinically, suspicion of ACR is dependent upon serum laboratory values, and diagnosis…2020 American Transplant Congress
Low Physiochemical Immunogenicity Scores Improve Long-Term Survival of Deceased Donor Kidney Transplants
*Purpose: A severe shortage of deceased donor kidneys limits access to kidney transplantation. Limited longterm graft function exacerbates this shortage as 12% of the waiting…2020 American Transplant Congress
Impact of Belatacept Conversion on Renal Function, Histology and Gene Expression in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
1Virginia Commonwealth University, Richmond, VA, 2ATAGC, Edmonton, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. Basic and…2020 American Transplant Congress
No Kidney after Liver Left Behind: An Analysis of the Organ Procurement and Transplantation Network “Safety Net” Policy
Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: Liver transplant (LT) recipients who develop persistent renal dysfunction face increased morbidity and mortality. These patients may be eligible for prioritization on the kidney…2020 American Transplant Congress
Change in the Willingness of Transplant Candidates to Accept Hepatitis C Virus Positive Deceased Donor Organs in the Era of Direct-Acting Antivirals
Transplant Center, Massachusetts General Hospital，Harvard Medical School, Boston, MA
*Purpose: Direct-acting antiviral (DAA) medications’ advent in 2014 very effectively changed the hepatitis C virus (HCV) treatment landscape and allowed post-transplant HCV therapy. We aimed…2020 American Transplant Congress
Does the New Heart Transplantation Allocation System Improve Access to Transplantation for Restrictive and Hypertrophic Cardiomyopathy Patients? A UNOS Database Analysis
*Purpose: Historically, patients with end-stage restrictive (RCM) and hypertrophic cardiomyopathy (HCM), experienced longer wait times and increased waitlist mortality while awaiting a heart transplant (HT)…
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