Am J Transplant, Volume 20, Suppl 3 Archives - Page 162 of 223 - ATC Abstracts

2020 American Transplant Congress
Less is More: A Single Brain Death Exam Improves Organ Donation Outcomes
A. J. Matar¹, H. Wichmann², L. Kenney², A. Subramanian³, J. Ratcliff⁴, V. Patel⁴, B. M. Tracy², R. B. Gelbard²
¹Surgery and Transplantation, Emory University, Atlanta, GA, ²Surgery, Emory University, Atlanta, GA, ³Surgery, Lawnwood Regional Medical Center, Fort Pierce, FL, ⁴Neurosurgery, Emory University, Atlanta, GA
*Purpose: The diagnosis of brain death in adults has historically required two brain death examinations (TBD) before considering organ donation. Despite American Academy of Neurology…
2020 American Transplant Congress
An Optimized Integrative Model Using Urinary Chemokines for Noninvasive Diagnosis of Acute Allograft Rejection
C. Tinel¹, A. Devresse¹, A. Vermorel¹, D. Marx², S. Caillard², C. Legendre¹, M. Rabant³, D. Anglicheau¹
¹Nephrology and Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Nephrology and Kidney Transplantation, Strasbourg University Hospital, Strasbourg, France, ³Pathology, Necker Hospital, Paris, France
*Purpose: The aim of this study was to optimize the performance of urinary chemokines C-X-C motif ligand (CXCL) 9 and CXCL10 as noninvasive diagnostic markers…
2020 American Transplant Congress
Low HLA Class I Epitope Mismatch Associated with Improved Pancreas Graft Survival in Simultaneous Pancreas-Kidney Transplantation
J. M. Ladowski, M. Romine, D. Kloda, C. Young, J. Locke, V. Hauptfeld-Dolejsek, J. Houp
University of Alabama-Birmingham, Birmingham, AL
*Purpose: Antibody-mediated rejection remains the principal cause of allotransplant graft failure. Human leukocyte antigen (HLA) matching between donor and recipients significantly reduces the risk of…
2020 American Transplant Congress
Getting to Yes Faster: Multifactorial Filters to Reduce Unwanted Offers
A. Toll, H. McGehee, J. Rosendale, D. Stewart, R. McTier
United Network for Organ Sharing, Richmond, VA
*Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: Using recursive…
2020 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies are Associated with Younger Age and Renal Dysfunction in Pediatric Kidney Transplantation
M. Pearl¹, E. T. Chambers², A. Kirk², R. Garro³, B. L. Warshaw³, P. Grimm⁴, R. Ettenger¹, E. Reed¹
¹UCLA, Los Angeles, CA, ²Duke, Durham, NC, ³Emory, Atlanta, GA, ⁴Stanford, Stanford, CA
*Purpose: The significance of non-HLA antibodies in renal transplantation remains unclear. In small single center retrospective studies, angiotensin II type 1 receptor antibody (AT1R-Ab) has…
2020 American Transplant Congress
Liver Transplant Recipients with High DSA at Time of Transplant Do Not Have Increased Rejection or Mortality
A. Demirag¹, B. Rawashdeh¹, S. L. Lennon¹, S. Pelletier¹, J. Iezzoni², K. Khutsisvhili³, S. Shumilina¹, K. Chittum¹, J. Oberholzer¹, P. Lobo⁴
¹Department of Surgery, University of Virginia Medical Cener, Charlottesville, VA, ²Department of Pathology, University of Virginia Medical Cener, Charlottesville, VA, ³Histocompatibility Laboratory, University of Virginia Medical Cener, Charlottesville, VA, ⁴Department of Medicine, University of Virginia Medical Cener, Charlottesville, VA
*Purpose: Currently, there is controversy regarding transplanting livers in setting of high HLA-class ll DSA especially since prior studies demonstrated enhanced acute rejections in this…
2020 American Transplant Congress
Association between Mycoplasma and Ureaplasma Airway Colonization, Ammonia Levels and Outcomes Post Lung Transplantation
B. Buzo¹, J. Preiksaitis¹, K. Halloran², J. Nagendran³, D. Townsend⁴, N. Zelyas⁵, W. Sligl⁴
¹Infectious Diseases, Univ. of Alberta, Edmonton, AB, Canada, ²Pulmonary Medicine, Univ. of Alberta, Edmonton, AB, Canada, ³Cardiac Surgery, Univ. of Alberta, Edmonton, AB, Canada, ⁴Critical Care Medicine, Univ. of Alberta, Edmonton, AB, Canada, ⁵Lab Med & Pathology, Univ. of Alberta, Edmonton, AB, Canada
*Purpose: Hyperammonemia syndrome (HS) is a rare complication that can occur after lung transplantation. This syndrome is characterized by increased ammonia levels with altered sensorium,…
2020 American Transplant Congress
Survival after Lung Transplantation by Discharge Immunosuppressive Regimen: An Analysis of Organ Procurement and Transplantation Network Data
W. S. Cherikh¹, B. J. Plucinski¹, S. Palmer², W. E. Fitzsimmons³
¹United Network for Organ Sharing, Richmond, VA, ²Duke University Hospital, Durham, NC, ³Fitzsimmons LLC, Vernon Hills, IL
*Purpose: As the optimal immunosuppressive (IS) regimen after lung (LU) transplant (TX) is unknown, we conducted an analysis to compare the effect of four different…
2020 American Transplant Congress
TRANSBIO Study: Clinical Evaluation of Immunobiogram, a Novel In Vitro Diagnostic Immunoassay to Guide Adjustment of Immunosuppressive Therapy in Kidney Transplantation
J. Pascual¹, C. Jiménez², M. Krajewska³, C. Kotton⁴, D. Seron⁵, J. Portolés⁶, O. Witzke⁷, S. S. Sorensen⁸, A. Andrés⁹, T. Díez¹⁰, A. Ortega¹⁰, I. Portero¹⁰
¹Consorci Mar Parc de Salut, Barcelona, Spain, ²La Paz Hospital, Madrid, Spain, ³Wroclaw Medical University, Wroclaw, Poland, ⁴Massachusetts General Hospital, Boston, MA, ⁵Vall d’Hebron Hospital, Barcelona, Spain, ⁶Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, ⁷University Hospital Essen, University Duisburg-Essen, Essen, Germany, ⁸Rigshospitalet, Copenhagen, Denmark, ⁹12 de Octubre Hospital, Madrid, Spain, ¹⁰Biohope Scientific Solutions for Human Health SL, Madrid, Spain
*Purpose: Immunobiogram (IMBG) is a first-in-class blood-based pharmacodynamic immunoassay that provides the sensitivity/resistance profile of each patient’s lymphocytes to a panel of immunosuppressive drugs (IS).…
2020 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis (NASH) by Single-Nucleus RNA Sequencing
C. Kuscu¹, A. Mouhammed², C. Kuscu³, A. R. Wolen³, J. D. Eason³, D. Maluf³, V. Mas³
¹Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ²Bioinformatics, University of Tennessee Health Science Center, Memphis, TN, ³Department of Surgery, University of Tennessee Health Science Center, Memphis, TN
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is a progressive disease and it constitutes a significant portion of the chronic liver diseases that affected more than…