ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    CD11b is a Novel Alternate Receptor for CD154 During Alloimmunity

    M. L. Ford, D. Liu

    Emory University, Atlanta, GA

    *Purpose: For decades, blockade of CD40-CD154 has been shown to be a highly effective means of inhibiting alloreactive T cell responses and inducing long-term graft…
  • 2020 American Transplant Congress

    Eosinophils Maintain Lung Allograft Tolerance by Sequestering CD8+ T Cells in Bronchial Associated Lymphoid Tissue

    Z. Mei1, Y. Guo1, A. Hata1, A. Banerjee1, D. Li1, A. Manafi1, B. Mahgoub1, D. Kreisel2, A. Gelman2, A. S. Krupnick1

    1Department of Surgery, University of Virginia, Charlottesville, VA, 2Department of Surgery, Washington University in St. Louis, St. Louis, MO

    *Purpose: It has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. But the role of eosinophils in long term maintenance…
  • 2020 American Transplant Congress

    Single Dose Rituximab and Anti-Thymocyte Globulin (ATG) Induction in Hypersensitized Kidney Transplant Recipients

    A. X. Wang, U. Wang, S. Busque, C. R. Lenihan

    Stanford University School of Medicine, Stanford, CA

    *Purpose: Hypersensitized kidney transplant recipients (calculated panel reactive antibody (cPRA) ≥98%) may represent a population at high risk of posttransplant immunologic events. While access to…
  • 2020 American Transplant Congress

    Incidence of Antibody Mediated Rejection in Living Kidney Transplant Recipients with Sensitizing History

    Y. Kakuta1, M. Okumi1, T. Kanzawa1, K. Unagami2, H. Ishida2, K. Tanabe1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan, 2Organ Transplant Regulation, Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: A donor-reactive alloimmune memory response can arise from prior exposure to foreign human leukocyte antigen by sensitization history in transplant recipients. Assessing risk levels…
  • 2020 American Transplant Congress

    Deep Learning for Living Donor Surgery: AI Recognition of Surgical Video to Develop Navigation Systems for Laparoscopic Nephrectomy

    M. Nishihara1, K. Iwadoh2, M. Noriyuki1, I. Koyama2, I. Nakajima2, M. Tonsho1

    1Transplant Surgery, International University of Health and Welfare, Mita Hospital, Tokyo, Japan, 2Kidney Surgery, Tokyo Women's Medical University Hospital, Tokyo, Japan

    *Purpose: Laparoscopic surgery for living donors requires high safety, thus establishing of navigation system for surgical operation is urged. The purpose of this study was…
  • 2020 American Transplant Congress

    Transplantation of HCV Positive Kidneys Confers Excellent Outcomes for HCV Infected and Uninfected Recipients

    J. Torabi, N. Muhdi, A. Montal, J. Melvin, Y. Miura, J. P. Rocca, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, O. Alani, E. Akalin, S. Greenstein, M. Kinkhabwala, J. A. Graham

    Montefiore Medical Center, Bronx, NY

    *Purpose: Hepatitis C positive (HCV+) donor kidneys were previously transplanted only into HCV infected recipients (D+/R+). Availability of direct acting anti-virals (DAA) has facilitated the…
  • 2020 American Transplant Congress

    Acute Rejection in the First Year is a Risk Factor for Subsequent Cardiac Events in Kidney Transplant Recipients

    F. Aziz, R. Tao, S. Parajuli, N. Garg, D. Mandelbrot, B. Astor, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: Cardiac events (CE) remain an important cause of morbidity and mortality after the first post-transplant year. We sought to determine whether acute rejection in…
  • 2020 American Transplant Congress

    Outcome of Large Donor-Recipient Age Gap in Live-Donor Renal Transplant in Tacrolimus Era

    K. Soliman1, T. Fulop1, M. Mohamed Ahmed1, A. Osman2, A. Posadas1, M. Casey1, V. Rao1, V. Rohan3, D. Dubay3, S. Nadig3, H. Ali4

    1Medicine, Medical University of South Carolina, Charleston, SC, 2Medicine, Cairo University, Cairo, Egypt, 3Surgery, Medical University of South Carolina, Charleston, SC, 4Medicine, Royal Stoke University, Royal Stoke, United Kingdom

    *Purpose: A large donor-to-recipient age gap among deceased-donor renal transplant (RT) patients leads to worse outcomes. However, the impact of this age gap among live-donor…
  • 2020 American Transplant Congress

    Kidney Transplant Results Comparing Two Formulations of Prolonged-Release Tacrolimus: Paired Study of Kidney Donors

    V. Lopez Jimenez, J. Alonso Titos, J. Gamez España, M. Cabello Díaz, D. Hernández Marrero

    Nephrology Department, Regional University Hospital, University of Malaga, IBIMA, REDinREN (RD16/0009/0006), Málaga, Spain

    *Purpose: Although the formulations of prolonged-release tacrolimus (Advagraf® and Envarsus®) are effective after kidney transplantation in terms of efficacy and safety, no paired analysis has…
  • 2020 American Transplant Congress

    Characterization of Gut Microbiome in Liver Transplant Recipients with Non-Alcoholic Steatohepatitis

    S. Sataphaty1, P. Banerjee2, J. Pierre3, R. Heda3, S. Dutta3, D. D. Higgins4, V. Mas5, S. Khan6, V. Mupparaju3, S. R. Nair7, J. D. Eason8, D. Kleiner9, D. Maluf10

    1Department of Surgery, Division of Hepatology and Sandra Atlas Bass Center for Liver Diseases, Northwell Health, NYC, NY, 2School of Public Health, University of Memphis, Memphis, TN, 3University of Tennessee Health Science Center, Memphis, TN, 4University of Memphis, Memphis, TN, 5James D Eason Transplant Institute, Memphis, TN, 6Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, NYC, NY, 7Department of Surgery, James D Eason Transplant Institute, Memphis, TN, 8Department of Surgery, James D Eason Transplant Institute, NYC, TN, 9Laboratory of Pathology/National Cancer Institute, Bethesda, WA, 10Department of Surgery_ University of Tennessee, James D Eason Transplant Institute, NYC, TN

    *Purpose: Non-alcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH) is a growing problem globally and recurs even after liver transplant (LT).…
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