Am J Transplant, Volume 20, Suppl 3 Archives - Page 156 of 223 - ATC Abstracts

2020 American Transplant Congress
Multi-Organ Procurement Organization Review of the Impact of Reactive Anti-HCV and HCV NAT Results
C. C. Muse, C. A. Hostetler, R. A. Squires, J. P. Orlowski
LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: Previously a single organ procurement organization (OPO) reviewed data from a 15 month cohort (1/1/2016 to 3/31/17) and concluded that donors who tested positive…
2020 American Transplant Congress
Hematopoietic Cell Transplantation and Solid Organ Transplantation: Outcomes of Sequential Transplantation in the United States
M. Gupta¹, M. Levine², D. Porter², R. Brazauskas³, S. Bo-Subait⁴, R. Phelan³, M. Battiwalla⁵, D. Buchbinder⁶, B. Hamilton⁷, B. Shaw³, P. Abt²
¹University of Kentucky, Lexington, KY, ²University of Pennsylvania, Philadelphia, PA, ³Medical College of Wisconsin, Milwaukee, WI, ⁴CIBMTR, NMDP, Minneapolis, MN, ⁵Sarah Cannon Blood Cancer Network, Nashville, TN, ⁶Children's Hospital of Orange County, Orange, CA, ⁷Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
*Purpose: Survival after solid organ transplantation(SOT) and hematopoietic cell transplantation(HCT) has steadily risen. Despite these improvements, SOT recipients may develop conditions requiring HCT, and HCT…
2020 American Transplant Congress
Association between Education and Waitlist Mortality, Access to Transplant, and Post-Transplant Survival among Patients with Alcohol-Associated Liver Disease
A. T. Strauss, J. Motter, D. Segev, A. Massie, T. Purnell, J. Hamilton, A. Gurakar, A. Cameron, J. Garonzik-Wang
Johns Hopkins University, Baltimore, MD
*Purpose: Alcohol-associated liver disease (ALD) is the leading indication for liver transplant (LT) and these patients have been shown to have worse outcomes compared to…
2020 American Transplant Congress
Evaluation of Apixaban Usage in Solid Organ Transplant Patients with Renal Impairment
L. Rakouki, R. Yau, C. Tunwar
Pharmacy, CHI St. Luke's Health-Baylor St. Luke's Medical Center, Houston, TX
*Purpose: There remains a gap in the literature for apixaban dosing recommendations for treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE) in special…
2020 American Transplant Congress
Public Information Needs about VCA Donation and Transplantation in the United States
H. Sung¹, A. Ferzola¹, J. Uriarte², N. Anderson², C. Cooney¹, G. Brandacher¹, E. Gordon², M. Henderson¹
¹Johns Hopkins University, Baltimore, MD, ²Northwestern University, Evanston, IL
*Purpose: Vascularized Composite Allotransplantation (VCA) involves transplantation of multiple tissues (e.g., skin, muscle, bone, nerves, blood vessels, etc.) as a structural unit from a donor…
2020 American Transplant Congress
Membrane Expression of CD163 and CD206 by Blood Monocytes is Upregulated in Kidney Allograft Recipients
I. Striz, L. Curnova, V. Svachova, M. Fialova, M. Novotny, O. Viklicky
Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Blood monocytes differentiating into tissue macrophages or dendritic cells are involved in multiple immune responses including reactions to the transplanted allograft. Peripheral monocytes can…
2020 American Transplant Congress
Two Pilot Studies Exploring the Diagnostic and Predictive Potential of Serum LAG3 and FGL1 in Kidney Transplant Recipients
Y. Li¹, L. Yan¹, Y. Li¹, C. Yang¹, Z. Wan¹, Y. An¹, Y. Bai¹, L. Wang¹, Y. Shi²
¹Department of Laboratory Medicine, West China Hospital, Chengdu, China, ²Department of Nephrology, West China Hospital, Chengdu, China
*Purpose: Lymphocyte activation gene 3 (LAG3), an immune checkpoint, plays an important role in the negative regulation of immune response and the induction of immune…
2020 American Transplant Congress
DAMPs and NLRP3 Inflammasome Response in Fatty Liver Grafts Preservation in Different Preservation Solutions
R. G. Bardallo¹, R. G. Teixeira-Silva², A. Panisello-Rosello³, E. Folch-Puy³, J. Rosello Catafau⁴, T. Carbonell⁵
¹Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain, ²Experimental Pathology, Instituto de Investigaciones Biomedicas de Barcelona, CSIC, Barcelona, Spain, ³Experimental Pathology, Instituto de Investigaciones Biomedicas de Barcelona, Barcelona, Spain, ⁴Experimental Pathology, Instituto de Investigaciones Biomédicas de Barcelona, CSIC, Barcelona, Spain, ⁵Cell Biology, Physiollogy and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain
*Purpose: Preservation solutions (UW, HTK and IGL-1) are widely used in clinical liver transplantation. It is well known that the composition of the preservation solution…
2020 American Transplant Congress
The Liver Regenerative Effect of Substance P after Major Hepatectomy in Rat Models
H. Ahn¹, Y. Kim¹, O. Kwon²
¹Surgery, Kyung Hee University, Seoul, Korea, Republic of, ²Surgery, Hanyang University, Seoul, Korea, Republic of
*Purpose: The hepatic damages are inevitable under liver surgery. Therefore, post-hepatectomy liver failure remains one of the most dangerous and life-threatening complications of hepatectomy. The…
2020 American Transplant Congress
3D Bioprinted Intrahepatic Cholangiocarcinoma Model and 7-Day Perfusion with Gemcitabine and Cisplatin: Modeling the Tumor Microenvironment and Response to Chemotherapy
A. M. Chen¹, W. Zhang¹, J. Sterner², L. Kennedy³, A. Isidan¹, E. Gramelspacher¹, H. L. Francis³, G. Alpini³, L. J. Smith², P. Li¹, B. Ekser¹
¹Division of Transplant Surgery - Indiana University, Indianapolis, IN, ²3D Bioprinting Core and Department of Radiology and Imaging Sciences - Indiana University, Indianapolis, IN, ³Division of Gastroenterology, Richard L. Roudebush VA Medical Center and Indiana University, Indianapolis, IN
*Purpose: Over 8,000 patients are newly diagnosed with cholangiocarcinoma (CCA) in the United States each year.Understanding the CCA microenvironment will facilitate the development of novel…