ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Distribution of High-Urgency Listing and Regional Variation before and after Implementation of the 2018 US Heart Allocation Policy

    T. Cascino1, M. Skeans2, V. Patel1, M. Colvin1

    1University of Michigan, Ann Arbor, MI, 2SRTR, Minneapolis, MN

    *Purpose: The demand for heart transplant exceeds organ availability. The Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) updated heart allocation policy in…
  • 2020 American Transplant Congress

    Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression

    T. Sigdel, A. Schroeder, J. Y. Yang, R. Sarwal, J. Liberto, M. Sarwal

    University of California San Francisco, San Francisco, CA

    *Purpose: The purpose of this study was to apply high-throughput metabolomics and machine learning to identify surrogate urine metabolite biomarkers for acute rejection vs. BK…
  • 2020 American Transplant Congress

    Endothelial Cells Internalize Apoptotic Exosome-Like Vesicles Through Phosphatidylserine-Dependent Macropinocytosis

    F. Migneault, M. Dieudé, A. Brodeur, N. Thibodeau, D. Beillevaire, M. Hébert

    CRCHUM, Montreal, QC, Canada

    *Purpose: Ischemia-reperfusion and rejection favor endothelial apoptosis, which in turn contributes to maladaptive vascular repair leading to transplant vasculopathy. Apoptotic endothelial cells (EC) release exosome-like…
  • 2020 American Transplant Congress

    Acute Kidney Injury in Deceased Organ Donors and Kidney Transplant Outcomes Using a Novel Data Source

    E. M. Sonnenberg, J. Hsu, J. Cohen, V. Potluri, M. H. Levine, P. L. Abt, P. P. Reese

    Perelman School of Medicine, University of Pennsyl, Philadelphia, PA

    *Purpose: The kidney shortage necessitates innovative approaches to expand the donor pool. Acute kidney injury(AKI) is common among deceased donors and a risk factor for…
  • 2020 American Transplant Congress

    Recurrent Diabetic Nephropathy Post Kidney Transplant is Associated with High Risk of Mortality

    A. Kukla, M. Merzkani, W. Park, B. Smith, S. Turkevi-Nagy, P. Zhang, X. Benavides, M. Morales Alvarez, A. Denic, A. Bentall, Y. Kudva, M. D'Costa, P. Alexander, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: The goal of the study was to determine the incidence of recurrent diabetic kidney disease (DKD) after kidney transplantation (KT) and assess its correlation…
  • 2020 American Transplant Congress

    Living Donor Liver Transplantation Demonstrated Superiority to Deceased Donor Transplantation after Adult-To-Adult Liver Transplantation in Cumulative Single-Center Retrospective Cohort Study of 19 Years

    T. Goto, T. Reichman, G. Sapisochin, I. McGilvray, M. Selzner, A. Ghanekar, M. Cattral, N. Selzner

    Multi-Organ Transplant Program, Toronto General Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada

    *Purpose: Living donor liver transplantation (LDLT) is an alternative way to deceased donor liver transplantation (DDLT). LDLT and DDLT showed similar short-term outcomes of recipient…
  • 2020 American Transplant Congress

    Posttransplant Program Evaluations: Long-Term Outcomes are More Relevant to Patients Than Short-Term Outcomes

    A. Wey, N. Salkowski, M. Skeans, B. Kasiske, A. Israni, J. Snyder

    SRTR, Minneapolis, MN

    *Purpose: Posttransplant evaluations with 1-year follow-up are criticized for not identifying clinically meaningful differences between programs, not being the right outcome for patients, or including…
  • 2020 American Transplant Congress

    Impact of Functional Status on Outcomes of Simultaneous Pancreas-Kidney Transplantation: Risks and Opportunities for Patient Benefit

    K. Lentine1, T. Alhamad2, M. Cooper3, Z. Zhang4, K. Woodside5, D. Dadhania6, S. Chang2, D. Axelrod7, M. Schnitzler4, R. Ouseph1, J. Snyder8, B. Kasiske8, R. Parsons9

    1Department of Medicine, Saint Louis University, Saint Louis, MO, 2Washington Univ, Seattle, WA, 3Georgetown Univ, Washington, DC, 4Saint Louis University, Saint Louis, MO, 5Univ of Michigan, Ann Arbor, MI, 6Weill Cornell, New York, NY, 7Univ of Iowa, Iowa City, IA, 8SRTR, Minneapolis, MN, 9Emory, Atlanta, GA

    *Purpose: The impact of functional status on survival among simultaneous pancreas-kidney transplant (SPKT) candidates and recipients is not well described.*Methods: We examined national Scientific Registry…
  • 2020 American Transplant Congress

    A Data-Driven Approach to Defining the Volume-Outcome Relationship in Liver Transplantation

    M. D. Bailey, E. L. Godfrey, W. C. Frankel, A. Rana

    Baylor College of Medicine, Houston, TX

    *Purpose: Patients with end-stage liver disease (ESLD) who undergo liver transplantation experience significant survival benefit, with a 1-year survival rate after liver transplantation of 91%.…
  • 2020 American Transplant Congress

    The Efficacy of Spheroidal Hepatocyte in Hepatocyte Transplantation

    K. Shibuya, M. Watanabe, R. Kanazawa, Y. Ganchiku, R. Goto, A. Taketomi

    Department of Gastroenterological Surgery Ⅰ Hokkaido University Graduate School, Sapporo, Japan

    *Purpose: Hepatocyte transplantation (HCTx) has been expected as a next generation cell therapy alternative to liver transplantation. Following HCTx, the liver function improves in many…
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