Am J Transplant, Volume 20, Suppl 3 Archives - Page 154 of 223 - ATC Abstracts

2020 American Transplant Congress
Wait Times in Pediatric Heart Transplant Candidates: Impact of Size and Blood Type Following the 2016 Allocation Policy Revision
R. J. Williams, M. Lu, L. A. Sleeper, S. Urbach, K. P. Daly
Department of Cardiology, Boston Children's Hospital, Boston, MA
*Purpose: To describe wait times for pediatric heart transplant (HT) candidates following institution of a new allocation system in March 2016.*Methods: The OPTN database was…
2020 American Transplant Congress
The Ratio between Naïve and Memory B Cells is Associated with Development of Early Donor-Specific Antibodies within the First Month after Lung Transplantation
A. Hitz¹, R. Bellmàs Sanz¹, F. Ius², J. Kühne¹, B. Wiegmann², W. Sommer², J. Salman², T. Siemeni², C. Kühn², M. Avsar², A. Haverich², I. Tudorache², G. Warnecke², C. Falk¹
¹Institute of Transplant Immunology, Hannover Medical School MHH, Hannover, Germany, ²Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School MHH, Hannover, Germany
*Purpose: After lung transplantation (LuTx), the development of early donor HLA-specific antibodies (eDSA) has been shown to be associated with antibody-mediated rejection (AMR) and poor…
2020 American Transplant Congress
Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation
M. Segovia¹, Y. Patel¹, S. Nagai², D. Sudan¹, S. Jafri²
¹Duke University Hospital, Chapel Hill, NC, ²Henry Ford Hospital, Detroit, MI
*Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…
2020 American Transplant Congress
Calibration of Donor-Derived Cell-Free DNA Criteria for Rejection with Molecular Diagnoses of Kidney Transplant Biopsies
I. Moinuddin¹, D. Kumar¹, L. Kamal¹, A. King¹, L. Kang¹, M. Levy¹, S. Bobba¹, D. Massey¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²Alberta Transplant Genomics Applied Centre, Edmonton, AB, Canada
*Purpose: Traditional microscopic histopathologic assessment (HDx) can be prone to error due to inter-observer variability as well as the non-specificity of some histologic lesions. Donor-derived…
2020 American Transplant Congress
microRNA-223 in MSCS-Derived Exosomes Protects Against Renal Ischemia/Reperfusion Injury Through Inhibiting Pyroptosis Pathway via Directly Targeting NLRP3
C. Ding, W. Xue
Department of Renal Transplantation, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
*Purpose: miR-223 is a well-studied miRNA that has been tested for abnormal expression in many diseases, and it has been found to play a regulatory…
2020 American Transplant Congress
Altering Homeostatic Repopulation with Thymic Irradiation and Donor Mesenchymal Stem Cell Infusions in a Nonhuman Primate Model
R. Schmitz, M. S. Mulvihill, Z. W. Fitch, T. How, F. Leopardi, A. D. Kirk
Department of Surgery, Duke University Medical Center, Durham, NC
*Purpose: Lymphocyte depletion and subsequent homeostatic repopulation present opportunities to shape the alloreactive immune repertoire to favor tolerance. We tested if the addition of thymic…
2020 American Transplant Congress
First U.S. DCD Heart Procured/Transplanted after Normothermic Regional Perfusion
A. L. Friedman¹, Z. N. Kon², D. E. Smith², B. Sullivan³, J. Carillo², N. Moazami²
¹LiveOnNY, New York, NY, ²Cardiothoracic Surgery, NYU Langone Transplant Institute, New York, NY, ³NYU Langone Transplant Institute, New York, NY
*Purpose: We successfully planned, procured and transplanted a heart after a Donation After Cardiac Death (DCD) protocol with post-declaration implementation of in vivo cardiopulmonary bypass…
2020 American Transplant Congress
Perspectives of Nephrologists and Urologists on Financial Incentives for Altruistic Non-Directed Living Kidney Donors
F. Aziz¹, B. Hafeeq¹, J. C. Gopinathan¹, R. Narayanan¹, A. Krishnakumar¹, N. A. Uvais.²
¹Nephrology, Iqraa International Hospital and Research Centre, Calicut, India, ²Psychiatry, Iqraa International Hospital and Research Centre, Calicut, India
*Purpose: Several strategies have been suggested to remove financial barriers that can arise from donating a kidney, including payment in the form of incentives, rewards…
2020 American Transplant Congress
Outcomes of CPRA 100% Deceased Donor Kidney Transplant Recipients Under the New Kidney Allocation System: A Single-Center Cohort Study
K. R. Jackson, J. Chen, E. Kraus, N. Desai, D. Segev, N. Alachkar
Johns Hopkins Hospital, Baltimore, MD
*Purpose: In light of changes in donor/recipient case-mix and increased cold ischemia times under KAS, there is some concern that cPRA 100% recipients might be…
2020 American Transplant Congress
Synergistic Impact of Obesity and Pre-sensitization in Kidney Transplant Recipients on the Long Term Allograft Survival
Y. Park¹, S. Lee¹, E. Ko¹, T. Ban², J. Min³, H. Yoon⁴, C. Yang¹, B. Chung¹
¹Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Internal Medicine, Eunpeyong St. Mary's Hospital, Seoul, Korea, Republic of, ³Internal Medicine, Bucheon St. Mary's Hospital, Seoul, Korea, Republic of, ⁴Internal Medicine, Incheon St. Mary's Hospital, Seoul, Korea, Republic of
*Purpose: Obesity is emerging as important health problems worldwide. In recent years, with the development of desensitization therapy, successful kidney transplantation has been performed even…