Am J Transplant, Volume 20, Suppl 3 Archives - Page 154 of 223 - ATC Abstracts

2020 American Transplant Congress
TPIAT Outcomes in Diabetic and Non-Diabetic Patients with Chronic Pancreatitis
M. A. Kanak, P. Saravanan, J. Kalivarathan, G. Hobbs, M. F. Levy
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplantation (TPIAT) is becoming the standard of care for patients with severe chronic pancreatitis (CP). However, it is necessary to…
2020 American Transplant Congress
Urinary APOA4 as a Biomarker for Chronic Renal Allograft Injury and Rapid Renal Function Decline in Kidney Transplant Recipients
H. Jeon¹, D. Shin¹, J. Oh¹, J. Park², K. Ko³, J. Kim³, S. Lee³
¹Department of Internal Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, ²Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, ³Department of Surgery, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of
*Purpose: Chronic renal allograft injury (CRAI) remains a major cause of allograft loss in kidney transplant recipients (KTRs). The aim of this study was to…
2020 American Transplant Congress
Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside
Y. Liu¹, T. Lu², C. Zhang¹, Z. Xue¹, R. Busuttil¹, J. Kupiec-Weglinski¹, H. Ji¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²Shanghai Jiaotong University, Shanghai, China
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…
2020 American Transplant Congress
Treg Stability Depends on Lymphotoxin Beta Receptor-Driven Migration
V. Saxena, W. Piao, L. Li, Y. Xiong, C. Palusckievicz, T. Simon, M. Shirkey, R. Abdi, J. S. Bromberg
University of Maryland, Baltimore, Baltimore, MD
*Purpose: Regulatory T cell (Treg) suppressor function for allograft survival requires maintenance of transcription factor Foxp3 and sequential migration from tissues to lymph nodes (LN).…
2020 American Transplant Congress
Improved Survival of Acute Liver Failure by “Off-the-Shelf” Bioartificial Liver Support System Using Immobilized Cryopreserved Hepatocyte Spheroids in Porcine Model
S. Lee¹, J. Lee², H. Park², Y. Kim², J. Noh³, J. Jung³, S. Lee³, H. Shin³, H. Yoon⁴, D. Lee³, S. Lee¹
¹Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of, ²Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea, Republic of, ³Biomedical Research Center, Lifeliver, Co. Ltd., Yongin, Korea, Republic of, ⁴Biomedical Research Center, Lifeliver, Co. Ltd., Seoul, Korea, Republic of
*Purpose: Acute liver failure (ALF) has a rapid and unpredictable onset with high mortality. The only current treatment is to transplant a donor organ but…
2020 American Transplant Congress
Natural Antibodies and Left Ventricular Assist Device Complications
S. B. See¹, D. Onat², E. Hittesdorf³, F. McDougan⁴, M. Yuzefpolskaya², V. K. Topkara², Y. Naka⁵, H. Takayama⁵, K. Takeda⁵, G. Milligan⁶, D. Wencker⁶, S. Hall⁶, M. Askar⁶, P. Kimball⁴, G. Wagener³, P. C. Colombo², E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, ²Department of Medicine, Columbia University Irving Medical Center, New York, NY, ³Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, ⁴Department of Transplant Surgery, Virginia Commonwealth University, Richmond, VA, ⁵Department of Surgery, Columbia University Irving Medical Center, New York, NY, ⁶Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX
*Purpose: Left ventricular assist device (LVAD) implantation is followed by a sharp increase in serum levels of IgG natural antibodies (Nabs) recognizing oxidation-specific epitopes (OSE)…
2020 American Transplant Congress
Strong Engagement of CD137 Suppresses Graft-Versus-Host Disease Through Dendritic Cells
H. Cho¹, J. Lee², B. Kwon³, S. Park⁴, H. Park⁴, K. Yoo², K. Park², J. Kim³, S. Kang³
¹Ulsan University Hospital, Ulsan, Korea, Republic of, ²Nephrology, Ulsan University Hospital, Ulsan, Korea, Republic of, ³Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea, Republic of, ⁴Surgery, Ulsan University Hospital, Ulsan, Korea, Republic of
*Purpose: We previously demonstrated that anti-CD137 agonist prevent acute graft-versus-host disease (GVHD) and chronic GVHD in the parent-into-unirradiated F1 acute or chronic GVHD model. Although…
2020 American Transplant Congress
Electroacupuncture Promotes Induction of Long-Term Allograft Survival by Enhancing Lymphatic Migration of CD4+Foxp3+ Tregs via Upregulating Their LTalpha1beta2 Expression
H. Liu, Y. Chen, F. Qiu, Z. Dai
Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China
*Purpose: Induction of long-term transplant survival without continuous global immunosuppression is a highly desired goal in transplantation. Electroacupuncture (EA) has been shown to regulate immunity…
2020 American Transplant Congress
Inducing Donor MHC Chimerism with Bone Marrow Derived Exosomes in Non-Human Primates
P. M. Patel¹, B. A. Gonzalez Nolasco¹, J. A. Morrissette¹, A. Prunevieille¹, K. J. Ahrens¹, J. M. O¹, D. C. Becerra¹, G. Benichou¹, J. C. Madsen²
¹Surgery, Center for Transplantation Sciences, Massachusetts General Hospital/Harvard Medical School, Boston, MA, ²Surgery, Center for Transplantation Sciences, Division of Cardiac Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, MA
*Purpose: Cardiac allograft tolerance in non-human primates (NHPs) has been achieved by our group via hematopoietic mixed chimerism consisting of an allogeneic bone marrow (BM)…
2020 American Transplant Congress
Lymphycyte Subset Test as a Determinant of Cytomegalovirus Prophylaxis in Renal Transplant Recipients
M. Kim, Y. Park, S. Mok, K. Jun, S. Kim, J. Kim, S. Yun, I. Moon, S. Park
Surgery, The Catholic University of Korea, Seoul, Korea, Republic of
*Purpose: Cytomegalovirus (CMV) infection is an important complication after kidney transplantation (KT). Anti-thymocyte globulin (ATG) increases a risk of CMV infection and the American society…