ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Evaluating Preformed Donor HLA Reactive T Cells Using PIRCHE-II Algorithm

    T. Tomosugi1, K. Iwasaki2, S. Sakamoto1, A. Kanda1, K. Futamura1, M. Okada1, T. Hiramitsu1, N. Goto1, S. Narumi1, Y. Watarai1, T. Kobayashi2, M. Niemann3, E. Spierings4

    1Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan, 2Kidney Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan, 3PIRCHE AG, Berlin, Germany, 4University Medical Center Utrecht, Utrecht, Netherlands

    *Purpose: De novo donor-specific HLA antibodies (dnDSA) production involves the indirect allorecognition pathway in which recipient CD4+T cells recognize donor-HLA-derived peptide and recipient HLA class…
  • 2020 American Transplant Congress

    Risk Factors for Early Multidrug-Resistant Infections in Solid Organ Transplant Recipients: How Impactful Are Donor-Derived Infections?

    T. T. Miller1, E. J. Kwak2, G. Floridia3, F. Tuzzolino3, A. Luca3, A. Mularoni3

    1School of Medicine, University of Pittsburgh, Pittsburgh, PA, 2Division of Infectious Diseases, University of Pittsburgh, Pittsburgh, PA, 3Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IRCCS-ISMETT), Palermo, Italy

    *Purpose: The purpose of this study is to evaluate risk factors for early post-transplant infections by multi-drug resistant gram-negative bacilli (MDRGNB).*Methods: We retrospectively assessed the…
  • 2020 American Transplant Congress

    Waiting List and Transplant Outcomes of Highly Sensitized Kidney Patients

    R. Schmitz, O. K. Jawitz, S. J. Knechtle, A. M. Jackson

    Department of Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Sensitized kidney transplant candidates represent a growing population on the waiting list. Transplantation of patients with high calculated panel reactive antibody (CPRA) can be…
  • 2020 American Transplant Congress

    Has Every Possible Life Been Saved?: Rummaging Through the Discard Heap

    A. L. Friedman, E. Marquez

    LiveOnNY, NY, NY

    *Purpose: To determine the reasons that deceased donor organs were allocated but not transplanted (TXP) in a large organ procurement organization (OPO).*Methods: All organs allocated…
  • 2020 American Transplant Congress

    Successful Liver-Kidney Transplantation in a Highly Sensitized Pediatric Patient

    M. Bock, M. Chandran, J. Goebel, E. Blanchette, M. Wachs, M. Adams, S. Sundaram

    Children's Hospital Colorado, Denver, CO

    *Purpose: While immunologically challenging and controversial, we report a successful case of same donor staged simultaneous liver-kidney transplant (SLK) in a highly sensitized child against…
  • 2020 American Transplant Congress

    High Estimated Glomerular Filtration Rate at the First Year after Kidney Transplantation is Associated with Worse Long-Term Graft Survival in Kidney Recipient

    H. Choi1, K. Huh2, M. Kim2, S. Kim2, Y. Kim2, B. Kim1

    1Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: High estimated glomerular filtration rate (eGFR) as well as low eGFR is associated with cardiovascular morbidity and mortality. The transplanted kidney in the recipient…
  • 2020 American Transplant Congress

    Change in Hypertension (HTN) Guidelines in Living Kidney Donors (LKDs) and Long-Term Renal Outcomes

    M. Merzkani1, A. Denic1, M. D'Costa1, L. Ricaurte1, R. Narasimhan1, X. Benavides1, A. Mullan1, J. Larson1, W. Kremer1, W. Park1, M. P. Alexander1, H. Chakkera2, S. Textor1, S. Taler1, M. Stegall1, N. Issa1, A. Rule1

    1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic Rochester, Scottsdale, AZ

    *Purpose: There is limited knowledge regarding the long-term renal outcomes in hypertensive LKDs. We performed a multicenter study assessing long-term outcomes with or without HTN…
  • 2020 American Transplant Congress

    Clinical Outcomes in Kidney Transplant Recipients Following Implementation of a Strategic Maintenance Reduction Protocol

    H. Perkins, K. Foster, N. Patel, H. Meadows, F. Bartlett, C. Perez, J. McGillicuddy, N. Pilch, M. Casey, M. A. Posadas-Salas, D. Taber

    Pharmacy, Medical University of South Carolina, Charleston, SC

    *Purpose: Post-transplant complications are commonly due to over-immunosuppression, particularly as it relates to infections. The purpose of this study was to assess clinical outcomes in…
  • 2020 American Transplant Congress

    Simultaneous Liver and Kidney Transplantation—The Lack of Influence of Pre-Formed DSA

    A. Bhansali, F. Mahir, M. Facciuto, R. Shapiro, J. Crismale, T. Schiano, G. De Boccardo

    Recanati-Miller Transplantation Institute, Mount Sinai Hospital, New York, New York, NY

    *Purpose: It is known that renal transplant recipients with preformed donor specific antibodies (DSA) have poorer outcomes associated with episodes of acute rejection (AR) and…
  • 2020 American Transplant Congress

    Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors

    A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

    Johns Hopkins Hospital, Baltimore, MD

    *Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of…
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