Am J Transplant, Volume 20, Suppl 3 Archives - Page 154 of 223 - ATC Abstracts

2020 American Transplant Congress
Development and Characterization of Decellularized Whole Human Livers for Increasing Donor Pool
A. Acun, R. Oganesyan, B. E. Uygun
Massachusetts General Hospital - Harvard Medical School, Boston, MA
*Purpose: Liver diseases are recognized as the second leading cause of mortality amongst all digestive diseases in the United States. Orthotopic liver transplantation leads to…
2020 American Transplant Congress
Outcomes of Kidney Transplant Recipients with Depression and Anxiety
D. Keys, S. Jackson, S. M. Riad, R. Spong, A. Matas
University of Minnesota, Minneapolis, MN
*Purpose: The outcomes of kidney transplantation in patients with depression and anxiety have been limited by small numbers. This is despite high prevalence of these…
2020 American Transplant Congress
Older Organs Transfer Senescence to Transplant Recipients
J. Iske¹, R. Maenosono¹, M. Seyda¹, T. Heinbockel¹, M. Koichiro¹, Y. Nian¹, T. Tchkonia², J. L. Kirkland², R. Abdi¹, A. Elkhal¹, S. G. Tullius¹
¹Brigham and Women's Hospital, Boston, MA, ²Mayo Clinic, Rochester, MN
*Purpose: Older organs represent an underutilized potential. Organ age, at the same time, augments alloimmune responses resulting into increased acute rejection rates. Senescent cells accumulate…
2020 American Transplant Congress
Clinically Adjudicated Deceased Donor AKI and Graft Outcomes
S. G. Mansour¹, N. Khoury¹, S. Vermani¹, R. Koladi¹, I. Hall², P. Reese³, S. Mohan⁴, M. Doshi⁵, M. Harhay⁶, J. Bromberg⁷, M. Thangamani⁸, P. Singh⁹, Y. Jia¹⁰, H. Thiessen-Philbrook¹⁰, E. Akalin¹¹, F. Weng¹², B. Schroeppel¹³, J. Greenberg¹, D. Moledina¹, F. P. Wilson¹, C. Parikh¹⁰
¹Yale, New Haven, CT, ²Utah Univ, Salt Lake City, UT, ³UPenn, Philadelphia, PA, ⁴Columbia, New York, NY, ⁵Univ of Michigan, Ann Arbor, MI, ⁶Drexel, Philadelphia, PA, ⁷Univ of Maryland, College Park, MD, ⁸Cornell, NY, NY, ⁹Thomas Jefferson, Philadelphia, PA, ¹⁰Johns Hopkins, Baltimore, MD, ¹¹Montefiore, Bronx, NY, ¹²St Barnabas, Livingston, NJ, ¹³Univ Hosp, Ulm, Germany
*Purpose: We previously reported that AKI in deceased donors isn't associated with graft failure. As deceased donors undergo significant hemodynamic changes, we hypothesized that reversible…
2020 American Transplant Congress
Compatible Pairs- Providingan Option to Upgrade
V. Chipman¹, M. Cooper², S. Flechner³, G. Hil⁴, D. Leeser⁵, D. Mandelbrot⁶, M. Ronin⁴, D. Segev⁷, S. Syed⁸, A. Thomas⁹, A. Waterman¹⁰, G. R. Roll¹¹
¹Kidney Transplant, UCSF, San Francisco, CA, ²Georgertown, Washington, DC, ³Cleavland Clinic, Cleavland, OH, ⁴NKR, Babylon, NY, ⁵East Carolina Univ, Greenville, NC, ⁶University of Wisconsin, Madison, WI, ⁷Johns Hopkins, Boltimore, MD, ⁸UCSF, San Francisco, CA, ⁹Johns Hopkins, Baltimore, MD, ¹⁰UCLA and Terasaki Research Institute, Los Angeles, CA, ¹¹Surgery, Division of Transplant, UCSF, San Francisco, CA
*Purpose: Compatible pairs (CPs) can enter an exchange program instead of donating directly. These pairs increase transplants (txp) by providing additional donors within an exchange…
2020 American Transplant Congress
HCV-Positive Donors Are Healthier and Inequitably Utilized in the United States
B. L. Da, T. Kushner, G. Kakked, J. Crismale, G. Ezaz, T. Schiano, B. Saberi
Liver Disease, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Increased utilization of HCV-positive (HCV+) liver allografts has been endorsed as a solution to the national organ shortage. Due to the opioid epidemic, there…
2020 American Transplant Congress
Evaluation of Intraoperative versus Extended Antibiotic Prophylaxis in Liver Transplantation
S. Hamel¹, C. Garza¹, C. Gamble², H. Boone³, L. Thomas⁴, D. L. Gorden⁵
¹Pharmacy, Vanderbilt University Medical Center, Nashville, TN, ²Quality, Vanderbilt Transplant Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ⁵Hepatobiliary Surgery and Liver Transplantation, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Perioperative antibiotic use has important implications for patient care, antimicrobial stewardship, and cost containment. There is limited data guiding the optimal duration of perioperative…
2020 American Transplant Congress
Possible Mechanism of Sensitization against Angiotensin Type II Receptor after LVAD Implantation
P. Kimball¹, V. Chau², F. McDougan¹, M. Flattery², K. Shah²
¹Surgery, VCUHS, Richmond, VA, ²Cardiology, VCUHS, Richmond, VA
*Purpose: Detection of antibody (Ab) against angiotensin-II receptor (AT1R) following VAD implantation portends poorer outcomes for heart transplantation (HT). However, the cause of this sensitization…
2020 American Transplant Congress
Multidimensional System to Dynamically Predict Graft Survival after Kidney Transplantation
M. Raynaud¹, O. Aubert¹, S. Jordan², M. Stegall³, J. Friedewald⁴, D. Glotz¹, C. Legendre¹, D. Segev⁵, C. Lefaucheur¹, A. Loupy, On behalf of the study NCT03474003¹
¹Paris Transplant Group, Paris, France, ²Cedars Sinai, Los Angeles, CA, ³Mayo Clinic, Rochester, MN, ⁴Northwestern University, Chicago, IL, ⁵Johns Hopkins, Baltimore, MD
*Purpose: Current prediction systems of kidney-graft loss do not integrate the dynamic effect of parameters assessed over the time course of kidney recipients. Recent dynamic…
2020 American Transplant Congress
Belatacept versus Tacrolimus Combined with Antithymocyte Globulin in Kidney Transplantation
J. Goldman¹, A. Mitrokhin², B. Trivedi¹, V. Vidyasagar¹, N. Vadivel¹, N. Goes³, M. Hart¹
¹Swedish Medical Center, Seattle, WA, ²SUNY, Brooklyn, NY, ³Permanente Medical Group, Oakland, CA
*Purpose: Belatacept (BELA) used for maintenance immunosuppression (IS) after kidney transplant (KT) shows similar graft and patient survival, but improved allograft function, despite more rejection…